Feel Younger (44)

Would you like: Help with Weight Loss Cholesterol Support Improved Heart Health Enhanced Mood If so, you may want to give CLA a try.What is CLA and where does it come from?CLA is short for Conjugated Linoleic Acid(s), which is, in essence, an omega-6 fatty acid, but a healthy one.CLA is a naturally occurring fatty acid that is produced by a bio-hydrogenation process in the rumen, and thus is present in dairy products and ruminant meat (9cis, 11 trans).28 different forms of CLA exist [1].The difference between these structures is that their double bonds are organized in different ways. It’s vital to keep in mind that something as small as this can make a massive difference to our cells.Traditional UseCLA supplements are most commonly sold because of their reputation for aiding weight loss [2].CLA is also sometimes used as a dietary supplement for bodybuilding.Story of DiscoveryIn 1987, researchers at the University of Wisconsin in Madison first discovered CLA.Dr. Pariza first noted an extract in beef, back in 1978, that appeared to be an anticarcinogenic, but it wasn’t until 1987 that he identified this extract to be CLA.Since the discovery, a surge of scientific studies and research have been conducted on how CLA affects body mass and other potential benefits it may have on human health.In the past, people received healthy doses of CLA through their diet, by consuming beef and dietary fats.However, the way cattle are raised has changed… and it is this change, as well as the change in people's diets today, that has lowered the amount of CLA people are able to ingest.The majority of cattle no longer graze in pastures on natural grass and other foods. Instead, they are fed meat products and processed grains.This has resulted in a decrease in cattle's internal production of CLA, meaning less conjugated linoleic acid is consumed from eating meat and dairy products.Furthermore, most people that worry about cholesterol and fat intake adjust their diets to eat less red meat and dairy products, which in turn reduces the amount of CLA in their diet.Fortunately, scientists have developed a process to convert the linoleic acid of pure safflower oil into conjugated linoleic acid.How does it work?CLA works in the following ways: Boosts metabolism, thus aiding obesity & weight management by reducing body weight, reducing BMI, total fat mass, fat percentage and fat burned while sleeping [3]. CLA can improve blood pressure by increasing adiponectin and endothelial nitric oxide synthase activity [4]. Helps to reduce bad cholesterol (HDL-cholesterol), without impacting and raises good cholesterol levels (LDL-cholesterol). Can help improve heart health by increasing the amount of C-reactive protein (CRP) in the blood, which is a marker for inflammation. People mainly use CLA to: Aid Weight Loss A study done on overweight Chinese subjects found that CLA supplementation (twice daily dissolved in milk) helped with weight loss over a 12-week period [5].The supplementation was found to reduce body weight, reduce BMI, reduce total fat mass, and reduce fat percentage.The treatment also reduced waist to hip ratio and reduced subcutaneous fat mass.Studies have shown that CLAs decrease lipid storage by increasing the rate of fat breakdown in fat tissue [6].The fatty acids also increase fatty acid oxidation and reduce glucose uptake in cultured fat cells.Improve Heart Health & CholesterolIn a study of 80 obese and hypertensive people, CLA combined with ramipril reduced blood pressure more than ramipril alone [7].Another study found that high intakes of both cis-9, trans-11 and trans-10, cis-12 CLA raised the level of HDL cholesterol in healthy women.HDL cholesterol promotes low cholesterol levels and healthy heart function [8].High levels of glucose result in major heart damage and heart problems. A study in rat cells found that cells pre-treated with CLA and then exposed to high glucose levels had reduced heart damage and a decreased risk of heart problems, than cells not pre-treated in the same conditions [9].Our CLA from Safflower oil is all natural (unlike most that are chemically altered), sugar free, hormone free, lactose free and doesn’t contain any nasty binders.Here at Feel Younger, we believe in providing strong doses at reasonable prices. Our CLA from Safflower oil softgels provide a 1000mg dose per softgel, and will cost you no more than $19, with discounts available on subscriptions for multiple bottles.How do you take it?Take one softgel with food, twice a day.Taking with food will help the body better utilize the CLA.Any cautions?Possible side effects of taking CLA can be excessive flatulence, bloating, nausea and diarrhoea.CLA can increase insulin resistance.ALWAYS consult a healthcare professional before taking any new supplements. Scientific References:  https://www.ncbi.nlm.nih.gov/pubmed/12045395  https://www.ncbi.nlm.nih.gov/pubmed/15159244  https://www.ncbi.nlm.nih.gov/pubmed/22261578  https://www.ncbi.nlm.nih.gov/pubmed/19300423  https://www.ncbi.nlm.nih.gov/pubmed/22261578  https://www.ncbi.nlm.nih.gov/pubmed/23956445  https://www.ncbi.nlm.nih.gov/pubmed/19300423  https://www.ncbi.nlm.nih.gov/pubmed/20140250  https://www.ncbi.nlm.nih.gov/pubmed/26826429

What is Magnesium?Magnesium is an important mineral that’s crucially important for your body to function properly.It’s the fourth most abundant mineral found in your body[2] and it’s essential to all living cells and vital for myriad physiological functions[3].The reason why the benefits are so numerous and varied is because of the many ways that optimal levels of magnesium are necessary to function optimally.For instance, magnesium is required for the production of ATP (the main source of energy in our cells)[4], and the production of DNA, RNA, and proteins[5].Magnesium plays an important role in cell-to-cell communication[6].Over 300 enzymes (biological catalysts that make chemical processes happen in our body) require the presence of magnesium to function properly[7].Because of its positive charge, magnesium stabilizes the cellular membranes[8].How common is magnesium deficiency?While a deficiency severe enough to warrant medical attention is relatively rare, some health professionals believe that suboptimal levels of magnesium are relatively common, with estimates as high as 75% of people in the US not having a sufficient intake,[16] let alone an optimal intake, which has yet to be precisely defined.As with any essential nutrient, here at Feel Younger we believe that it’s always ideal to test your magnesium levels to be sure if it would be beneficial to take.The best tests for Magnesium are generally considered to be: RBC (red blood cell) or intracellular magnesium, to get a true understanding of overall deficiency.The more common tests are plasma or serum magnesium, which are much cheaper and easily available, but which are less of a true reflection of your body’s stores of magnesium, as your body will tend to keep your plasma and serum levels in a tight range in all but severe cases of deficiency.RBC (red blood cell) or intracellular magnesium tests, on the other hand, are considered to give a more accurate indication of true, overall levels of magnesium stores in the cells, which is what actually matters when assessing if levels are optimum.If you’re unable to access these tests however, then, given that Magnesium is a natural substance that is very safe for the vast majority of the population (see below for exceptions), it seems reasonable to try it, if you would like to support your body to Feeling Younger and Healthier, especially if you identify with some of the early signs of deficiency listed above.What causes Magnesium Deficiency?The most commonly understood causes of Magnesium Deficiency include[17]: a poor diet type 2 diabetes digestive problems such as Crohn’s disease long-term vomiting or diarrhoea kidney problems long-term use of diuretics some medicines (for example, fluid tablets and medicines for ulcers or reflux) can cause low magnesium levels if taken for long periods alcoholism In addition, some healthcare professionals point to the fact that, even in the case of a relatively good diet, it’s an established fact that the soil in which our food grows is 75%-90% lower in essential minerals like magnesium than it was 100 years ago.[18]So whether you’re eating plants, which can only get the minerals from the soil, or whether you’re eating animals that ate those plants, the results is the same: the food we’re eating is more mineral depleted, and therefore magnesium depleted, than it was up until relatively recently in our evolution.Finally, there is strong evidence that stress itself depletes magnesium[19]. This creates a vicious cycle where stress depletes magnesium, and then lowered magnesium reduces stress. Presumably, in order to break this cycle, you would need to replenish magnesium as well as reduce stress.What’s the Best Form of Magnesium to Take?There are many different forms of magnesium available, including citrate, sulfate, oxide, chloride and malate.However, the form that’s considered the best, the most easily absorbed by the body, is Magnesium Glycinate.Forms of magnesium that are less well absorbed and cheaper, like for instance magnesium oxide, have a laxative effect. As a general rule, the less well absorbed the form of magnesium is, the more of a laxative effect it’ll have.When consuming mineral supplements, the best form is generally considered to be when it’s chelated (chemically bonded) to an amino acid. Why is this? Because minerals in their raw form are inorganic, meaning that the body does not recognise them as food, often doesn’t absorb them well, and then also struggles to excrete them.Conversely, when a mineral is bonded to an amino acid, or chelated, this makes the mineral and Organic Mineral i.e. it’s the same form found in food, and so your body recognises the magnesium as food, and absorbs it a lot better.Magnesium Glycinate then, the type sold by Feel Younger, is considered the best form of magnesium because it’s bonded to Glycine, an abundant amino acid in the body which has a whole host of it’s own benefits[20], including: Glycine is one of the building blocks of the body’s most powerful natural antioxidant, glutathione Necessary to make collagen, for healthy skin Can improve sleep quality Can help keep blood sugar balanced May protect the liver and the heart Can protect against muscle loss. Although Glycine is not considered as an essential amino acid, because the body is capable of making its own, if necessary, many healthcare professionals consider it a good idea to increase glycine intake, either through natural foods like bone broth, or via supplementation.Feel Younger is proud to present our Magnesium Glycinate, containing 425mg of Elemental Magnesium per serving, which is close to the recommended daily amount for most people, enough to make up for the shortfall in almost any diet.How do you take Feel Younger ® Magnesium Glycinate?Ideally take with water directly before eating a meal, for maximum absorption, but can be taken any time, or as directed by a healthcare professional.Are there any cautions?Though magnesium supplements are generally considered safe, you should check with a healthcare professional before taking them, especially if you have a medical condition.The mineral supplement may be unsafe for people who take certain diuretics, heart medications, or antibiotics[21].Most people who take magnesium supplements don’t experience side effects, but magnesium can cause gut-related issues such as diarrhea, nausea, and vomiting, especially when used in large doses[22].It’s important to note that people with kidney issues are at a higher risk of experiencing adverse effects related to magnesium supplements[23].Always consult a qualified healthcare professional before making any changes to your diet or lifestyle. Scientific References: https://www.healthline.com/nutrition/magnesium-benefits https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592895/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775240/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439441/ http://jn.nutrition.org/content/144/1/55.long http://www.racgp.org.au/afpbackissues/2005/200508/200508woolhouse.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439441/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775240/ https://www.ncbi.nlm.nih.gov/pubmed/26166051 http://www.racgp.org.au/afpbackissues/2005/200508/200508woolhouse.pdf https://www.ncbi.nlm.nih.gov/pubmed/26166051 https://www.ncbi.nlm.nih.gov/pubmed/26166051 http://www.racgp.org.au/afpbackissues/2005/200508/200508woolhouse.pdf https://www.ncbi.nlm.nih.gov/pubmed/26166051 https://www.ncbi.nlm.nih.gov/pubmed/26166051 https://www.healthline.com/nutrition/magnesium-deficiency-symptoms https://www.healthdirect.gov.au/magnesium-deficiency https://www.scientificamerican.com/article/soil-depletion-and-nutrition-loss/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761127/. https://www.healthline.com/nutrition/glycine https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/#h9 https://pubmed.ncbi.nlm.nih.gov/26404370/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637834/

Would you like: Improved Mood Lower Anxiety and Stress Reduced Appetite Better Sleep How can 5-HTP help with this?Optimal levels of Serotonin can potentially give you all these benefits and more, as 5-HTP is a direct precursor to Serotonin.There is also some evidence that 5-HTP can potentially help with headaches, weight loss and even fibromyalgia.What is 5-HTP?5-hydroxytryptophan (5-HTP) is an amino acid that is a precursor of Serotonin and Melatonin in the brain. It is usually made in the body from the amino acid L-Tryptophan.Serotonin helps regulate your mood naturally. When you serotonin levels are normal, you feel: Happier Calmer More focused Less anxious More emotionally stable More confidant A 2007 study found that people with depression often have low levels of serotonin. Serotonin deficiency has also been linked to anxiety and insomnia.Melatonin is a hormone produced by the pineal gland in your brain, from Serotonin [1].It’s primarily responsible for regulating your body’s circadian rhythm to manage your natural sleep cycle [2].5-HTP in supplement form is extracted from the seeds of the plant Griffonia simplicifolia, an African shrub.How 5-HTP Helps Improve MoodThe effects of 5-HTP on symptoms of low mood have been well studied.While the exact cause of low mood is largely unknown, some researchers believe that a serotonin imbalance may influence your mood in a way that leads to depression [3].5-HTP supplements are thought to improve low mood by increasing serotonin levels.In fact, several small studies have found that 5-HTP reduced symptoms of depression. However, two of them did not use placebos for comparison, limiting the strength of their findings [4] [5].Reduced Appetite by Increasing Feeling of Fullness5-HTP may increase feelings of fullness, causing you to eat less and lose weight.Weight loss can increase the production of hormones that make you feel hungry, like Ghrelin. These feelings of constant hunger can make losing weight difficult and unsustainable in the long term [6] [7].5-HTP may counteract these hunger-inducing hormones, working to suppress appetite and help you lose weight [8].In one study, 20 people were randomly assigned to receive either 5-HTP or a placebo for two weeks. The results showed that those who received 5-HTP consumed 435 fewer calories per day, compared to the placebo group [9].Also, 5-HTP primarily inhibited the intake of calories from carbohydrates, which was associated with better blood sugar control [10].This is presumably because a craving for carbohydrate is partially based on a desire to increase serotonin, as carbohydrate rich foods increase blood serotonin levels.Many other studies have also found that 5-HTP increased feelings of fullness and aided weight loss in overweight or obese people [11] [12].Finally, animal studies have shown that 5-HTP may reduce excessive food intake due to stress or depression [13].Why try Feel Younger® 5 HTP 200mg Serotonin SupportOur 5-HTP is high quality, high purity, all natural, sugar free, hormone free and contains no nasty binders. We also believe in giving you an effective quantity and at a reasonable price, which is why we provide you 200mg a serving, 30 servings, for a maximum cost of only $19 (with greater discounts for subscriptions or purchases of multiple bottles.How do you take 5 HTP 200mg Serotonin Support?Take capsules with water.The recommended instructions for 5-HTP use depends on your reason for taking it.Here are some general guidelines with scientific references: Weight management: 2 capsules, 30 minutes prior to a meal [14].Mood enhancement: 1 capsule, 1-2 times per day with meals. [15]. Sleep aid: 1-2 capsules, 30–45 minutes before bed. Stack with Sleep Aid Ultra to increase effectiveness [16]. Any cautions?Some people may experience nausea, diarrhea, vomiting and stomach pain when taking 5-HTP supplements. These side effects are dose-dependent, meaning they get worse when increasing your dose [17].To minimize these side effects, start with a dose of 50–100 mg (½ to 1 capsule) once a day and increase to the appropriate dose over a two-week period [18].Some medications increase serotonin production. Combining these medications with 5-HTP may cause dangerous serotonin levels in your body. This is called serotonin syndrome, a potentially life-threatening condition [19].Medications that may increase your body’s serotonin levels include certain antidepressants, cough medicines or prescription pain relievers.Since 5-HTP may also promote sleep, taking it with prescription sedative medications, such as Klonopin, Ativan or Ambien, may cause too much sleepiness.Due to the potential for negative interactions with other medications, ALWAYS consult your doctor or pharmacist before taking 5-HTP supplements. Scientific References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676828/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334454/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471964/ https://www.ncbi.nlm.nih.gov/pubmed/6967194 https://www.ncbi.nlm.nih.gov/pubmed/28787372 https://www.ncbi.nlm.nih.gov/pubmed/29360396 https://www.ncbi.nlm.nih.gov/pubmed/20150577 https://www.ncbi.nlm.nih.gov/pubmed/16846858 https://www.ncbi.nlm.nih.gov/pubmed/9705024 https://www.ncbi.nlm.nih.gov/pubmed/9705024 https://www.ncbi.nlm.nih.gov/pubmed/2468734 https://www.ncbi.nlm.nih.gov/pubmed/1722953 https://www.ncbi.nlm.nih.gov/pubmed/14724051 https://www.ncbi.nlm.nih.gov/pubmed/9705024 https://www.ncbi.nlm.nih.gov/pubmed/11869656 https://www.ncbi.nlm.nih.gov/pubmed/19417589 https://www.ncbi.nlm.nih.gov/pubmed/3536521 https://www.ncbi.nlm.nih.gov/pubmed/9727088 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865832/

Would you like: Improved Hair, Skin and Nail Health Increased Metabolism Healthier Brain Function Immune System Support How can Biotin help with this?Optimal levels of Biotin can potentially give you all these benefits and more.Biotin works as a coenzyme to help break down food, such as carbohydrates, fats and protein which in turn, may lead to increased energy levels.Biotin is essential for myelin sheath formation, a fatty substance that encompasses nerves and facilitates nerve impulse conduction. As such, Biotin deficiency can delay myelination.Vitamin B7 (Biotin) also plays a crucial role in white blood cell development.However, Biotin is most commonly used for:Healthy Skin - Biotin helps maintain the mucous membranes of the skin. Biotin also plays a crucial role in the metabolization of fat, which is necessary for maintaining healthy skin.Healthy Nails - A biotin deficiency may lead to brittle nails.Healthy Hair - Many hair products that claim to encourage healthier, stronger hair contain Biotin. Biotin deficiency may lead to hair loss, which indicates that the vitamin might be involved in keeping the hair healthy.What is Biotin?Also known as vitamin B-7 or vitamin H - Biotin is a coenzyme for carboxylases, the enzymes that assist in the metabolic processing of fats, proteins, and carbohydrates for energy production [1].Biotin is a water-soluble vitamin. This means it is not stored in your body for long. Your body does not manufacture it naturally, either. However, bacteria in your gut (called intestinal flora) can produce Biotin.Biotin is also needed for the development of white blood cells and a deficiency can be linked to impaired immune function and an increased risk of infection [2].How was it discovered?Biotin was first identified as a nutritive requirement of yeast. Originally called vitamin H, it was isolated in pure form in 1935; its structure was established in 1942, after it had been shown to be required by animals. Evidence for the necessity of biotin appeared with the discovery in 1927 that the addition of uncooked egg white to a diet that is otherwise nutritionally adequate, can produce toxicity and disease. This is because egg white contains a specific protein, avidin, that combines with biotin and thus prevents its absorption.Optimal Biotin levels Increase MetabolismBiotin is a coenzyme for carboxylases, the enzymes that assist in the metabolism of fats, proteins, and carbohydrates for energy production [3].These enzymes are essential for the following processes: Gluconeogenesis, the metabolic pathway that produces glucose from non-carbohydrate sources including amino acids [4]. Cellular energy production [5]. The use of branched-chain amino acids (e.g., leucine, isoleucine, and valine) for neurotransmitter production and energy [6]. Synthesis and breakdown of fatty acids for energy [7]. Insulin release [8]. Inadequate vitamin B7 levels in the body can slow down metabolism, which may lead to fatigue, digestive problems, and weight gain [9].Healthy Brain Function requires Optimal Biotin levelsBiotin is required for myelin sheath formation, a fatty substance that surrounds nerves and facilitates nerve impulse conduction. As such, biotin deficiency can delay myelination [10].Biotin deficiency may also lead to a number of other neurological symptoms, including seizures, lack of muscle coordination, learning disabilities, hallucinations, depression, and lethargy. Most of these conditions can be resolved with biotin supplementation when they are caused by biotin deficiency [11].  Optimal Biotin levels Support the Immune SystemBiotin increases the production of Th1 cytokines like IL-1β and IFN-γ, which are essential for eliciting an immune response to combat bacterial and viral infections [12].Poor levels of vitamin B7 are associated with decreased antibody synthesis, T cell decay, and lower amounts of spleen cells and T cells in both animals and humans [13].Decreased rates of cellular proliferation during Biotin deficiency may account for some of these adverse effects on immune function [14].Biotin is a coenzyme for carboxylases, the enzymes that assist in the metabolism of fats, proteins, and carbohydrates for energy production [15].How do you know if you’d benefit from more Biotin?There are several factors that can deplete your Biotin or increase your need for Biotin. These include:The BTD gene encodes biotinidase, an enzyme that recycles biotin. Biotinidase transports free biotin through the bloodstream and attaches biotin to other proteins [16]. Certain SNPs related to the BTD gene can increase your dietary requirement for Biotin.Lipoic acid competes with vitamin B7 for binding to the sodium-dependent multivitamin transporter (SMVT) in the intestine, so long-term use of lipoic acid could result in depleted vitamin B7 levels [17].Similarly, large doses of vitamin B5 (pantothenic acid) have the potential to compete with vitamin B7 for absorption by the SMVT [18].Prolonged use of antibiotics like tetracycline and sulfonamides can reduce biotin levels because they kill biotin-producing bacteria in the intestines [19].Furthermore, some anticonvulsants such as primidone and carbamazepine inhibit vitamin B7 absorption. Chronic anticonvulsant use can also increase vitamin B7 breakdown [20].Raw egg whites contain the protein avidin, which binds biotin tightly and inhibits its absorption [21].Smoking accelerates biotin breakdown, especially in women, resulting in marginal biotin deficiency [22].Chronic alcohol consumption can inhibit intestinal biotin absorption [23].You can do a blood test to assess Biotin levels, but a more sensitive and accurate test to measure for suboptimal biotin levels is for the urinary metabolites 3-Hydroxypropionic Acid (3-HPA) and 3-Hydroxyisovaleric Acid. Talk to your Practitioner to arrange these tests for you if you think you may be low.Why try Feel Younger® Biotin 10,000mcg for Hair, Skin and NailsOur Biotin capsules are high quality, high purity, contain no binders and are vegetarian and vegan friendly.Here at Feel Younger, we believe in supplying effective quantities, at reasonable prices… and that’s why a bottle of our Biotin capsules gives you a 10,000 mcg dose and costs a maximum of $15, with larger discounts available for subscriptions of purchases of multiple bottles.How do you take Biotin 10,000mcg for Hair, Skin and Nails?Take 1 capsule a day with water, preferably 20-30 minutes before a meal, or with a meal, depending on the advice of your healthcare practitionerALWAYS consult your doctor or pharmacist before taking Biotin supplements, especially as biotin supplementation can provide inaccurate results on some blood tests.Any cautions?Taking too much Biotin may cause skin rashes, digestive upset, problems with insulin release and kidney problems.Biotin is generally considered safe and no toxicity has been reported for doses up to 300,000 mcg/day orally and 20,000 mcg intravenously [24].Since it is a water-soluble vitamin, vitamin B7 overdose is unlikely as excess amounts are excreted in the urine [25]. Scientific References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508090/ https://jn.nutrition.org/content/130/2/335S.full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508090/ https://www.ncbi.nlm.nih.gov/pubmed/18613815/ https://www.ncbi.nlm.nih.gov/pubmed/19727438 https://www.ncbi.nlm.nih.gov/pubmed/15930469 https://www.ncbi.nlm.nih.gov/pubmed/15968460 https://www.ncbi.nlm.nih.gov/pubmed/19727438 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726758/ https://www.ncbi.nlm.nih.gov/pubmed/18545994 https://www.ncbi.nlm.nih.gov/pubmed/21696988 http://jn.nutrition.org/content/133/3/716.full https://www.ncbi.nlm.nih.gov/pubmed/88554 https://www.ncbi.nlm.nih.gov/pubmed/14991266 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508090/ https://ghr.nlm.nih.gov/gene/BTD https://www.ncbi.nlm.nih.gov/pubmed/9516450 https://www.ncbi.nlm.nih.gov/pubmed/23578027 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726758/ https://www.ncbi.nlm.nih.gov/pubmed/15539280/ https://www.ncbi.nlm.nih.gov/pubmed/14747666/ https://www.ncbi.nlm.nih.gov/pubmed/15447901 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064116/ https://www.ncbi.nlm.nih.gov/pubmed/25787192 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726758/

Would you like… To Focus more Easily Improved Cognition Better Brain Function Improved Memory Sharper Thinking Increased Alertness Improved Mood If so, you may want to give our Brain Boost Plus, Neuro Brain and Focus Formula a try!The combinations of ingredients found in this supplement can potentially also give you: Antioxidant support Anti-inflammatory support Increased energy Improved skin health Improved eye health Blood pressure support Improved heart health Boosted immunity Better bone health Blood sugar regulation Why is it important to support your brain?The brain is arguably the most important organ in your body - without it, we wouldn’t be able to carry out any of our daily functions.The brain controls our motor skills, vision, temperature, hunger, emotions, touch, thought and just about every process that helps to maintain and regulate our bodies [1].There are a variety of factors that can lead to your brain ageing prematurely, or becoming ‘unhealthy’, such as: Lack of good quality sleep [2] Poor diet & overeating [3] Not enough exercise [4] Smoking [5] Obesity [6] High blood pressure [7] High cholesterol levels [8] Social isolation [9] Spending too much time in dimly lit environments [10] Often overlooked, Deficiency or suboptimal levels of nutrients that are important to the brain will also contribute to inferior brain health. Can you test for an ‘unhealthy’ brain?There are a variety of tests that can be used in different situations to help determine if something serious is going on with your brain.Some of these include:Balance testCT scan (computed tomography)EEG (electroencephalography)ElectromyographyMRI (magnetic resonance imaging)MRA (magnetic resonance angiography - a type of MRI scan)And more.However, as these tests are generally expensive and hard to get, most people rely on evaluating symptoms such as decreased memory, focus and clarity of thinking.Speak to your physician to determine the best course of action if you have any concerns.The Top 9 Ways to Support Your Brain:To keep your brain functioning at optimal capacity, there are some lifestyle changes that you can make: Get enough good quality sleep, every night. For most adults, this is 7-8 hours of deep uninterrupted sleep. If sleep is something you struggle with, check out our Sleep Aid Ultra page. Eat an organic diet with plenty of high nutrient density foods. This will provide your brain with most of the nutrients and minerals it needs for optimal function. Exercise regularly. Half an hour of physical activity most days, or around 150 minutes a week. Stop smoking.   Maintain a healthy weight, and don’t overeat. Even too much healthy food can lead to weight gain. Minimize stress and lower your blood pressure. Meditating is a great way to reduce stress, and try natural supplements, such as our 5 HTP, Serenity Anti-Stress Support, Saffron Pure Extract OR Organic Ashwagandha with Black Pepper. Socialize more often. Spend more time in natural light and brighter lit rooms earlier in the day. Provide your brain with minerals and vitamins that are essential for it to function optimally: Vitamin A - Vitamin A is crucial to brain function, behavior and learning [11].Vitamin C - Your brain requires huge amounts of oxygen to function, which means it is extremely susceptible to oxidative stress. Vitamin C is a powerful antioxidant and helps to reduce oxidative stress [12].Calcium - Calcium is essential for optimal blood flow to the brain [13].Vitamin D - Essential for brain health, deficiency in Vitamin D can contribute to brain fog, low mood and can impact cognitive health [14].Magnesium - Optimal levels of magnesium in the body is crucial for brain health. Deficiency of magnesium (or low levels of) is commonly found in people who are stressed [15].Vitamin B1 - A deficiency of thiamine (vitamin B1) can contribute to increased confusion, can be of detriment to your ability to think clearly as well as reducing your awareness of your surroundings [16].Vitamin B2 - Riboflavin vitamin b2) can help to reduce inflammation and oxidative stress to nerves in the brain, both of which can contribute to headaches and migraines [17].Vitamin B3 - Niacin (vitamin B3) is another B vitamin that plays an important role in the health of your brain. It’s involved in making and repairing DNA, cell signaling and acts as an antioxidant [18].Folate - Suboptimal mental function can be linked to low folic acid (folate) levels in the blood.A randomized controlled trial over 2 years showed that 400mg folic acid supplementation improved measures of brain function and decreased blood levels of proteins that are linked to Alzheimer’s disease [19].Selenium - Selenium is a powerful antioxidant [20], and people with Alzheimer’s have been found to have lower levels of selenium in their blood [21].Copper - Essential for brain function, too much or too little copper in the body can be linked with neurodegeneration [22].Manganese - Manganese is required for many functions in the body, which includes normal brain and nervous system function.It’s another powerful antioxidant (potentially one of the most important) [23] that can help to protect your brain against free radicals, as well as improving your brain function [24].Potassium - Potassium plays an important role in the cardiovascular system, helping to get blood to the brain [25].Choline - Choline is needed to produce a neurotransmitter called acetylcholine, which is crucial to regulate intelligence, mood and memory [26].Grape Seed Extract - Grapes contain flavonoids, which possess powerful antioxidants and anti-inflammatory properties. Studies have shown that grape seed extract may help to improve cognitive status and antioxidant levels in the brain, while preventing memory loss [27].GABA - GABA (gamma aminobutyric acid) is an amino acid that functions as a neurotransmitter in the brain. When GABA attaches to a GABA receptor in the brain, it has a calming effect [28].Bilberry Fruit Extract - Bilberry fruit extracts have been shown to help improve memory (both working and long-term) in older adults [29].And many more!We understand that it’s not always easy, nor is it practical to implement a variety of lifestyle changes at once.We’d advise that you make as many of those changes listed further up this page as possible, but to do so 1 or 2 at a time, make sure they stick and then implement a couple more.In the meantime, you can support your body with the essential nutrients and minerals it needs that can help you to boost your brain's function.That’s why we’ve included the above ingredients into our Brain Boost Plus formula, and included other minerals and vitamins that we think are worth taking to support the health of your brain, such as: Vitamin E [30], Iron [31], Biotin [32], Vitamin B5 [33], Vitamin B6 [34], Zinc [35], Chromium [36], Molybdenum [37], DMAE Bitartrate [38], L-glutamine [39], Green Tea Extract [40], Bacopa Extract [41], Inositol [42], N-Acetyl L-Tyrosine [43], Olive Leaf [44], Cinnamon Bark Extract [45], Licorice Root Extract [46], Boron [47], DHA [48], Vanadyl [49], Phosphatidylserine [50], Huperzine A [51]. By combining the ingredients listed on this page, with our unique proprietary blend in an easy to swallow capsule, we’ve taken the stress out of buying each of these ingredients separately, researching and experimenting how much of each you should take and then incorporating them into your diet/supplement regime.Here at Feel younger, we believe in providing strong doses at reasonable prices. Our Brain Boost Plus capsules provide a 1,004 mg dose that will cost you no more than $29, with discounts available on multiple bottle and subscription purchases.How Do You Take Feel Younger® Brain Boost Plus, Neuro Brain and Focus Formula?Take two capsules a day with your morning meal.Any Cautions?ALWAYS consult a healthcare professional before taking any new supplements. Scientific References https://www.ncbi.nlm.nih.gov/books/NBK279302/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143346/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437759/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258000/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543069/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598577/ https://www.health.harvard.edu/heart-health/blood-pressure-and-your-brain https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844833/ https://www.nia.nih.gov/news/social-isolation-loneliness-older-people-pose-health-risks https://pubmed.ncbi.nlm.nih.gov/32933226/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169332/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649700/ https://www.medschool.umaryland.edu/news/2021/University-of-Maryland-School-of-Medicine-Study-Finds-Calcium-Precisely-Directs-Blood-Flow-in-the-Brain.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970300/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761127/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659035/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ https://pubmed.ncbi.nlm.nih.gov/26828517/ https://pubmed.ncbi.nlm.nih.gov/29255930/ https://pubmed.ncbi.nlm.nih.gov/19033020/ https://pubmed.ncbi.nlm.nih.gov/24668390/ https://www.sciencedirect.com/science/article/pii/S0301008214000124 https://pubmed.ncbi.nlm.nih.gov/22072939/ https://pubmed.ncbi.nlm.nih.gov/12505649/ https://pubmed.ncbi.nlm.nih.gov/23558164/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252552/ https://pubmed.ncbi.nlm.nih.gov/21871550/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231020/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024810/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276978/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789770/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728061/ https://pubmed.ncbi.nlm.nih.gov/20423560/ https://pubmed.ncbi.nlm.nih.gov/15207438/ https://pubmed.ncbi.nlm.nih.gov/864168/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760805/ https://pubmed.ncbi.nlm.nih.gov/28899506/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153866/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554709/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084775/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074804/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466762/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974064/ https://pubmed.ncbi.nlm.nih.gov/7889884/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772061/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077345/ https://clinicaltrials.gov/ct2/show/NCT04920305 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930088/

Would you like: Help Regulating Blood Sugar Levels Improved Sensitivity to the Hormone Insulin Antioxidant Support Reduced Inflammation Supported Brain Function Help Losing Weight/Boosted Metabolism Improved Cardiovascular Health If so, you may want to try Ceylon Cinnamon. It has also been shown to: Help Fight Bacterial and Fungal Infections Improve Digestion Support Bone Health & Thyroid Function Due to it Being Rich in Manganese Help with Menstrual Cramps & Pains Preserve Oral Health What is Ceylon Cinnamon and Where Does it Come From?Cinnamon is a spice made from the inner bark of trees from the laurel family (Lauraceae - bushy evergreen trees) and is scientifically known as Cinnamomum.There are two main types of cinnamon that are widely available: Ceylon cinnamon: Cinnamomum verum, also known as “true” cinnamon. This type is more expensive and less toxic to the liver because it’s much lower in coumarin, a natural constituent that promotes blood thinning. Cassia cinnamon: Cinnamomum cassia. This type is more commonly available and is generally what you’ll find at a store or restaurant [1]. Because of the liver toxicity potential of the cheaper, cassia form of cinnamon, we personally would recommend only using Ceylon Cinnamon. The cinnamon in Feel Younger’s Cinnamon product is 100% Ceylon Cinnamon and 0% Cassia Cinnamon.Ceylon is native to Sri Lanka and southern parts of India.It’s tan-brown in color and contains many tight sticks with soft layers. These features provide a highly desirable quality and texture.It’s known to have a more delicate and mild sweet flavor in comparison to Cassia Cinnamon.Approximately 50–63% of its essential oil is cinnamaldehyde, which is quite low compared to cassia. This explains its milder aroma and flavor [2].Traditional UseCinnamon has been used as an ingredient throughout history [3], dating back as far as Ancient Egypt. It used to be rare and valuable and was regarded as a gift fit for kings.It was also recognised for its medicinal qualities [4], and was used to help with digestion issues [5], oral conditions, boost memory, purify blood, promote healing [6], help with colds, flu and sore throats, provide relief from menstrual cramps and discomfort.Cinnamon teas were also thought to be beneficial to oxidative stress related illnesses in humans, due to it being high in anti-oxidative qualities [7].How Does it work?Ceylon Cinnamon has many health benefits which have been studied in human and animal trials: In human trials, cinnamon can lower fasting blood sugar levels [8] Cinnamon reduces insulin resistance [9] which is one of the key hormones that regulate metabolism and energy use. Ceylon cinnamon increases levels of the master antioxidant, glutathione (in rats) [10]. Cinnamaldehyde/Cinnamon activates Nrf2, the most important pathway for increasing our natural and innate antioxidant defense [11]. Both the twigs and leaves of Cinnamon are highly anti-inflammatory [12]. Two compounds found in cinnamon appear to inhibit the buildup of a protein called tau in the brain, which is one of the hallmarks of Alzheimer’s disease [13]. Cinnamon may help reduce total cholesterol, LDL (bad) cholesterol, and triglycerides, while HDL (good) cholesterol remained stable [14]. A large study concluded that cinnamon can also help increase HDL cholesterol [15]. People Mainly Use Ceylon Cinnamon For It’s Antioxidant Qualities Antioxidants protect your body from oxidative damage caused by free radicals.Cinnamon is loaded with powerful antioxidants, such as polyphenols [16].In a study that compared the antioxidant activity of 26 spices, cinnamon wound up as the clear winner, even outranking “superfoods” like garlic and oregano [17].In fact, it is so powerful that cinnamon can be used as a natural food preservative [18].Studies show that this spice and its antioxidants have potent anti-inflammatory properties [19].Blood Sugar RegulationCinnamon is well known for its blood-sugar-lowering properties.Apart from the beneficial effects on insulin resistance, cinnamon can lower blood sugar by several other mechanisms.First, cinnamon has been shown to decrease the amount of glucose that enters your bloodstream after a meal.It does this by interfering with numerous digestive enzymes, which slows the breakdown of carbohydrates in your digestive tract [20].Second, a compound in cinnamon can act on cells by mimicking insulin [21].This greatly improves glucose uptake by your cells, though it acts much slower than insulin itself.Numerous human studies have confirmed the anti-diabetic effects of cinnamon, showing that it can lower fasting blood sugar levels.The effective dose is typically 1–6 grams or around 0.5–2 teaspoons of cinnamon per day.Brain Function Support & ProtectionCinnamon may help delay cognitive impairment. A study on rats found cinnamon to improve cognition and reduce oxidation in the brain [22].Cinnamon may help with food cravings. By targeting a chemical in the brain involved in glucose and cholesterol (insulin), eating cinnamon may help you lose weight through reduced food intake [23].Cinnamon can help boost memory [24].Cinnamon is a great source of manganese. Two teaspoons of cinnamon provides about half the RDA of manganese, a powerful antioxidant that is essential for brain and body health [25].One study used Cinnamon aromatherapy on Children with ADHD, and found that it increased their attention [26].Here at Feel Younger, we believe in providing strong doses at reasonable prices. Our Ceylon Cinnamon Capsules provide a 1200mg dose of some of the finest and purest Ceylon Cinnamon on the market.We’re proud to say that Our Ceylon Cinnamon is high quality, high purity, all natural, organic, non GMO, made in the USA and contains no nasty fillers or binders. It is also lactose free and is vegan and vegetarian friendly.60 Capsules will cost no more than $19, with discounts available on multiple bottles or subscription orders.How do you take it?Take 1-2 Ceylon Cinnamon Capsules once a day, with water or preferably with a carbohydrate containing meal.Any cautions?As Ceylon Cinnamon is effective at lowering blood sugar levels, it can lead to tiredness, dizziness and possibly fainting - the biggest risk are people already taking medications for diabetes.ALWAYS consult a healthcare professional before taking any new supplements. Scientific References: http://www.fao.org/docrep/x5326e/x5326e07.htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854496/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488098/#bib4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003790/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488098/#bib1  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488098/#bib6  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488098/#bib5  https://www.ncbi.nlm.nih.gov/pubmed/19930003  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901047/  https://www.ncbi.nlm.nih.gov/pubmed/10641152  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101712/  https://www.ncbi.nlm.nih.gov/pubmed/16131142  https://www.ncbi.nlm.nih.gov/pubmed/19433898  https://www.ncbi.nlm.nih.gov/pubmed/14633804  https://www.ncbi.nlm.nih.gov/pubmed/24019277  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003790/  https://www.ncbi.nlm.nih.gov/pubmed/16190627  https://www.ncbi.nlm.nih.gov/pubmed/10077878  https://www.ncbi.nlm.nih.gov/pubmed/25629927  https://www.ncbi.nlm.nih.gov/pubmed/21538147  https://www.ncbi.nlm.nih.gov/pubmed/11506060  http://www.ncbi.nlm.nih.gov/pubmed/24559058  http://www.ncbi.nlm.nih.gov/pubmed/24811817  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097886/  http://www.ncbi.nlm.nih.gov/pubmed/1444472  https://www.cinnamonvogue.com/DOWNLOADS/ADHD_and_cinnamon_study.pdf

Would You Like: Detoxification Support Antioxidant Support Gastro-Intestinal Support Improved Immune System Enhanced Nutrition Enhanced Mood If so, you may want to give Chlorella a try! It has also been shown to: Improve Cholesterol Help Regulate Blood Pressure Enhance Aerobic Endurance Reduce Risk of Anemia During Pregnancy Help with Allergies Have Anti-Aging Properties Promote Eye Health Support Liver Health What is Chlorella and Where Does it Come From?Chlorella is a single celled, green freshwater algae [1]. Its impressive nutritional profile has led some to call it a “super food.” While its exact nutrient content depends on growing conditions, the species used and how supplements are processed, it’s clear it packs several beneficial nutrients, they include: Protein: Chlorella is 50–60% protein. It’s a complete protein source, meaning it contains all nine essential amino acids [2]. Vitamin B12: Some types of chlorella may also contain vitamin B12, but more studies are needed [3]. Iron and vitamin C: Chlorella can be a good source of iron. Depending on the supplement, it can provide anywhere from 6–40% of your daily needs. It’s also a terrific source of vitamin C, which helps you absorb iron [4]. Other antioxidants: These microscopic green cells provide a wide range of antioxidants [5]. Other vitamins and minerals: Chlorella provides small amounts of magnesium, zinc, copper, potassium, calcium, folic acid and other B vitamins [6]. Omega-3s: As with other algae, chlorella contains some omega-3s. Just 3 grams of chlorella contains 100 mg of omega-3s [7]. Fiber: In large quantities, chlorella can be a great source of fiber, although most supplements won’t provide even 1 gram of fiber per dose [8]. Because chlorella has a hard cell wall that humans cannot digest, you must take it as a supplement to reap its benefits (broken wall) [9].Chlorella is also high in chlorophyll – a green pigment that plants use to make energy from sunlight and helps rid the body of toxins.The majority of Chlorella that is available in the U.S is grown in Japan or Taiwan.Theoretically, Chlorella simply needs sunlight, freshwater and a few minerals to grow, and therefore is available worldwide - usually found next to lakes with freshwater.Traditional UseChlorella is sold extensively as a supplement or nutraceutical product [10] and is mainly used for nutrition and as medicine.Chlorella is being used all around the world, in countries such as Japan, the USA, Europe, and more. In East Asia, it is consumed with pancakes, tea and rice.It is believed to have many health benefits, such as reducing blood sugar and cholesterol, protecting the heart and liver, helping to prevent anemia, supports detoxing, helps combat oxidative stress, may improve mental health and enhance physical performance.Story of DiscoveryChlorella is believed to have been born around 2 billion years ago, and is thought to be the “source of life on earth”.Due to its microscopic size, it wasn’t discovered until the late 19th century.In 1890, A Dutch scientist called Beijerinck discovered a beautiful, small green plant that was just about visible under a microscope.The name given to this tiny green plant was “chlorella”, in which the Greek word “chloros” (meaning green) and the Latin word “ella” (meaning small) were combined.Interest in Chlorella production began in the 1960s, when a company in Japan started to culture it on a large scale.How does it work? Chlorella has been hailed for its ability to help the body “detox”. Animal studies have shown that it’s effective at helping to remove heavy metals and other harmful compounds from the body [11]. Chlorella contains several compounds that are considered antioxidants, including chlorophyll, vitamin C, beta-carotene, lycopene and lutein [12]. Many sources claim chlorella eases digestion and reduces bloating. Chlorella has been found to enhance the immune response in both animal and human studies. In one study men produced more antibodies when taking chlorella than when they took a placebo [13]. Chlorella is packed with nutritional content such as protein, vitamin B12, iron, vitamin C, a wide range of antioxidants, small amounts of magnesium, copper, calcium, folic acid, zinc, potassium, other B vitamins, Omega 3 fatty acids and large quantities of fiber [14]. Chlorella contains the highest concentration in the world of the amino acid Tryptophan, which is the precursor to serotonin - a neurotransmitter that helps relax you, reduce anxiety and depression and improves your mood.   People use Chlorella for many things, such as: Help with Detoxing Small amounts of some heavy metals, such as iron and copper, are essential for the body to function properly - but they can be toxic in larger amounts.While it’s quite rare to have dangerous levels of these heavy metals in your body, exposure to heavy metals through pollution or certain jobs, such as mining, increase the risk of dangerously high levels building up in your system [15].Algaes such as chlorella, have been found to reduce the toxic effect of heavy metals in the liver, brain and kidneys in animals [16].Chlorella has also been shown to help lower the amount of other harmful chemicals that can sometimes be found in foods, such as dioxin, which is a hormone disruptor that can contaminate animals in the food supply.This evidence seems to suggest that chlorella may help enhance your body’s natural ability to clear toxins.Antioxidant SupportChlorella contains many compounds that are considered to be antioxidants, such as vitamin C, lycopene, lutein, chlorophyll, and beta-carotene,Some of these antioxidants seem to reduce the production of advanced glycation end products (AGEs), which drive many of the complications of diabetes [17].A human study showed chlorella supplements increased antioxidant levels in cigarette smokers, who are at a higher risk of oxidative damage [18].Increased Immune ResponseIn a trial of 51 healthy participants, Chlorella tablets enhanced immunity. They increased NK cell activity, IL-1beta, and the Th1 response in people who ingested these tablets for 8 weeks [19].Intense exercise can weaken the immune system. In a placebo-controlled study performed in 10 female athletes, 5 weeks of Chlorella supplementation prevented the decrease in immune function (measured by salivary immunoglobulin A) during a training camp [20].Another study of 15 men, revealed that salivary IgA was increased in participants when they ingested Chlorella tablets for 4 weeks [21].A study of 35 pregnant women showed increased IgA levels in the breast milk of women that consumed Chlorella for 6 months before giving birth. Higher levels of IgA in breast milk helps reduce the risk of infection in nursing infants [22].Chlorella protected mice from E. coli and Listeria monocytogenes infection in two animal trials [23].In mice, Chlorella counteracted the effect of a chemotherapeutic drug (Cyclophosphamide) that suppresses the immune system by recovering NK cell function and increasing Th1 cytokines (IL-2, IL-12, TNF-a, IFN-y) [24].Our Chlorella capsules are high quality, high purity, all natural, vegan and vegetarian friendly and do not contain any nasty fillers or binders.Here at Feel Younger we believe in providing high doses at reasonable prices. Our Chlorella capsules contain a 500mg dosage, and will cost no more than $24, with multiple bottle discounts and subscription savings available.How do you take it?Take one capsule twice a day, with water - preferably 20-30 minutes before a meal.Any cautions?Chlorella is generally recognized as safe by the FDA, but some people may experience side effects such as nausea and abdominal discomfort. ALWAYS consult a healthcare professional before taking any new supplements. Scientific References:  https://www.ncbi.nlm.nih.gov/pubmed/26561078  http://www.sciencedirect.com/science/article/pii/S1364032114002342  https://www.ncbi.nlm.nih.gov/pubmed/24803097  https://www.ncbi.nlm.nih.gov/pubmed/26561078  https://www.ncbi.nlm.nih.gov/pubmed/26561078  https://www.ncbi.nlm.nih.gov/pubmed/26561078  http://onlinelibrary.wiley.com/doi/10.1111/j.1747-0080.2011.01569.x/full  https://www.ncbi.nlm.nih.gov/pubmed/26561078  http://www.sciencedirect.com/science/article/pii/S1364032114002342  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537823/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654245/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131561/  https://www.ncbi.nlm.nih.gov/pubmed/21906314  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551956/#:~:text=These%20Chlorella%20products%20contain%20a,33%25%2C%20dry%20weight).  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168898/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303853/  https://www.ncbi.nlm.nih.gov/pubmed/26561078  https://www.ncbi.nlm.nih.gov/pubmed/23865357  https://www.ncbi.nlm.nih.gov/pubmed/22849818  https://www.ncbi.nlm.nih.gov/pubmed/23227811  https://www.ncbi.nlm.nih.gov/pubmed/21906314  https://www.ncbi.nlm.nih.gov/pubmed/17472477  https://www.ncbi.nlm.nih.gov/pubmed/3015799  https://www.ncbi.nlm.nih.gov/pubmed/28684674

Would You Like: Increased Energy Levels Increased Mitochondrial Function Help with Migraines Lower Blood Pressure Increased Muscle Performance During Exercise and/or reduced Muscle Pain Improved Fertility If so, you may want to try Co Enzyme Q10, also known as Ubiquinone.Co Enzyme Q10 can potentially help with all of these problems as well as having other benefits such as: Improved Gut Health Improved Brain, Heart & Lung Health More balanced Blood Sugar Levels Improved Mood Skin Protection from UV Radiation  What is CoQ10?Coenzyme Q10 (CoQ10) is a key compound found in all cells in the body. It is a coenzyme, which means it helps enzymes work more effectively.How does CoQ10 work?CoQ10 is mainly found in the membrane of mitochondria, where it is used to make energy [1].It is also located in cell membranes and lipoproteins – such as LDL and HDL – where it acts as a powerful antioxidant. CoQ10 stabilizes cell membranes and helps cells work properly [2].Supplementing CoQ10 can help: Increase energy levels and help with exercise performance [3] Boost mitochondrial function [4] Protect against free radicals and inflammation [5]  Improve heart health [6] Reduce blood sugar levels and blood pressure [7] Help with migraines [8] Improve fertility [9] Reduce the side effects of statins [10]   People mainly use CoQ10 to, Increase Mitochondrial Function for Improved Cellular Energy ProductionEnergy-demanding organs in your body such as the brain, heart, kidneys, muscle and liver have the highest levels of CoQ10 all of which contain many mitochondria and use a lot of energy [11].Abnormal mitochondrial function can cause calcium uptake to be increased by cells, free radicals to be excessively produced, and a decrease in antioxidant protection. This can result in low energy in the brain cells and can even cause migraines [12].Potentially Improve MigrainesSince CoQ10 is largely found in the mitochondria of the cells, it has been shown to improve mitochondrial function and help decrease the inflammation that may occur during migraines [13].A study showed that CoQ10 supplementation was three times more likely to reduce the number of migraines than a placebo in 42 people [14].Additionally, CoQ10 deficiency has been observed in people suffering from migraines.A larger study showed that 1,550 people with low CoQ10 levels experienced fewer and less severe headaches after treatment with CoQ10 [15].Furthermore, it seems that CoQ10 can not only help treat migraines but may also prevent them [16].Increase Exercise PerformanceOxidative stress can affect muscle function, and thus, exercise performance [17].Similarly, abnormal mitochondrial function can reduce muscle energy, making it hard for muscles to contract efficiently and sustain exercise [18].CoQ10 can help exercise performance by decreasing oxidative stress in the cells and improving mitochondrial functions [19].In fact, one study investigated the effects of CoQ10 on physical activity. Those supplementing with 1,200 mg of CoQ10 per day for 60 days showed decreased oxidative stress [20].Furthermore, supplementing with CoQ10 can increase power during exercise and reduce fatigue, both of which can improve exercise performance [21].Improve Brain, Heart & Lung HealthThe brain is very susceptible to oxidative damage due to its high fatty acid content and its high demand for oxygen.It is this oxidative damage that enhances the production of harmful compounds that could affect memory, cognition and physical functions [22].CoQ10 may help reduce these harmful compounds build up in the brain.CoQ10 (100 – 320 mg/day) improved exercise capacity in patients with heart problems by increasing the ability of the lungs and heart to deliver oxygen to muscles [23].Out of all of your organs, your lungs have the most contact with oxygen, which makes them extremely susceptible to oxidative damage.Increased oxidative damage in the lungs and poor antioxidant protection, including low levels of CoQ10, make it more likely for lung issues such as asthma and chronic obstructive pulmonary disease (COPD) to occur [24].Furthermore, it has been shown that people suffering from these present lower levels of CoQ10 [25].A study showed that supplementing with CoQ10 helped reduce inflammation in people who had asthma, as well as their need for steroid medications to help treat it [26].Another study showed improvements in performance during exercise in COPD sufferers. This was observed through better tissue oxygenation and heart rate after supplementing with CoQ10 [27].How do you know if you would benefit from taking Co Q10?Various issues, including nutrient deficiencies, reduce the body’s ability to make CoQ10 or cause CoQ10 to be used up faster than it can be replaced. In these cases, supplementation can be helpful or may even be necessary [28].While it’s not a very common test, you absolutely can do a blood test to see if you have optimal blood levels of Co Enzyme Q10, and thereby you can deduce if you would potentially benefit from supplementing Co Enzyme Q10.Our CoQ10 capsules are high quality, high purity, all natural, vegetarian and vegan friendly and contains no nasty fillers or binders.Here at Feel Younger, we believe in providing strong doses at reasonable prices. Our Co Enzyme Q10 capsules provide a 200mg dose per capsule, and will cost you no more than $35, with discounts available on subscriptions for multiple bottles.How do you take it?Take one capsule a day. CoQ10 is fat soluble, so it should ideally be taken with a meal containing fat so your body can absorb it.Any cautions?Taking CoQ10 before you go to bed may cause insomnia in some people, so it's best to take it in the morning or afternoon.CoQ10 supplements can interact with some common medications, including blood thinners, antidepressants and chemotherapy drugs.Avoid using ubiquinone together with other herbal/health supplements that can also lower blood pressure.ALWAYS consult your doctor or pharmacist before taking CoQ10 supplements, especially if you are on any medications. Scientific References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178961/  https://www.ncbi.nlm.nih.gov/pubmed/9266510/  https://www.ncbi.nlm.nih.gov/pubmed/11375753  https://www.ncbi.nlm.nih.gov/pubmed/25126052  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299230/  https://www.clevelandheartlab.com/blog/the-new-heart-benefits-of-coenzyme-q10/#:~:text=CoQ10%20has%20already%20been%20shown,as%20muscle%20pain%20and%20weakness.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276825/  https://www.ncbi.nlm.nih.gov/pubmed/24331360  https://www.ncbi.nlm.nih.gov/pubmed/19447425  https://www.ncbi.nlm.nih.gov/pubmed/2247468/  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178961/  https://www.ncbi.nlm.nih.gov/pubmed/24331360  https://www.ncbi.nlm.nih.gov/pubmed/21586650  https://www.ncbi.nlm.nih.gov/pubmed/15728298  https://www.ncbi.nlm.nih.gov/pubmed/17355497  https://www.ncbi.nlm.nih.gov/pubmed/27670440  https://www.ncbi.nlm.nih.gov/pubmed/11375753  https://www.ncbi.nlm.nih.gov/pubmed/23182644  https://www.ncbi.nlm.nih.gov/pubmed/21681167/  https://www.ncbi.nlm.nih.gov/pubmed/20886510/  https://www.ncbi.nlm.nih.gov/pubmed/19644406/  https://www.ncbi.nlm.nih.gov/pubmed/20673763  https://www.ncbi.nlm.nih.gov/pubmed/16882678  https://www.ncbi.nlm.nih.gov/pubmed/16289557  https://www.ncbi.nlm.nih.gov/pubmed/21080098  https://www.ncbi.nlm.nih.gov/pubmed/16873952  https://www.ncbi.nlm.nih.gov/pubmed/8241703  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807419/

If you’d like to… Alleviate Symptoms of IBS Prevent or Reduce Diarrhea and Constipation Relieve Acid Reflux, Indigestion & Heartburn Lessened Gas & Bloating Increase Nutrient Absorption & Facilitate Digestion of Difficult Foods Optimize Your Body’s Ability to Break Down Carbohydrates, Proteins and Fats Support the Health of Your Colon Support The Healthy Bacteria in Your Intestines to Improve Digestive Health Restore Your Digestive Tract’s Natural Microbiome After Antibiotics You may want to give our Digestive Enzyme Probiotic Blend supplement a try!Our Digestive Enzyme and Probiotic Blend can also potentially give you a whole host of other health benefits, such as: Immune System Support Improved Heart Health Improved Mood & Anxiety Reduced Cholesterol Improved Weight Loss Reduced Pain & Inflammation Why is it Important to Support Your Gastrointestinal System & Digestion?Your gastrointestinal tract (gut) is a long tube that stretches from the mouth, all the way to your anus. It is responsible for 2 extremely important processes in our body. The first process is digestion.No matter how healthy (or not) your diet may be, optimal gut health is important for digestion so that you can absorb nutrients from food efficiently, utilize the building blocks that you need to maintain your body, and efficiently convert the food you eat into energy.Digestive enzymes are proteins that your body makes (mainly in your pancreas, but also in your small intestine, stomach and mouth) to break down food so your body can absorb the nutrients.For example, the digestive enzyme lipase is made to break down fats into glycerol and smaller fatty acids. The digestive enzyme lactase is made to help break down the natural sugar contained within milk which is called lactose.The second extremely important process that your digestive tract is significantly responsible for is your immune system. In fact, around 70% of your immune system is in your gut, which means good gut health is essential for optimal immune function to fight off bacteria, viruses and other pathogens that are dangerous to our bodies and can make us unwell.A healthy gut should contain many billions of “good” bacteria which multiply rapidly and create an acidic environment in the intestines so that the “bad” bacteria isn’t able to proliferate. The balance of these bacteria is often referred to as the gut microbiome (referring to microbes that are present in your digestive system).When your gut is not in good health, it will struggle to get rid of toxins (like endotoxin, believed to be a key factor in premature aging [1]) and substances that are left over from metabolic processes (metabolic waste) that must be excreted because they cannot be used by our bodies.What Impacts the Health of Your Gut & Digestion?If there is a problem with your digestive tract then digestive symptoms such as diarrhea, constipation, bloating, excess gas, abdominal pain, acid reflux and more can develop. But poor gut health can cause inflammation throughout the body, leading to a myriad of different health issues.In fact, ancient traditional modalities of health and healing, like Ayurvedic Medicine, actually believed that ‘all’ ill health had its origins in the gut.The gut is also known as an “extension of the brain” because its walls are lined with a system of neurons that help to govern the function of the gastrointestinal tract, which is known as the intrinsic or enteric nervous system. Again, this was known for thousands of years by Ancient Eastern systems like Taoism, the origin of Acupuncture and Chi Kung, who often referred to the gut as the ‘second brain’.Poor gut health has also been linked to the development of autoimmune disorders.There are many things that can damage the health of your gut and result in worsened digestion, such as: Genetic Factors (see Genetic Insights for more info on how your genetics may increase the likelihood of having gut issues.) Poor diet, including excess sugar and processed foods Nutritional Deficiencies Eating in a stressed state, usually leading to eating too quickly and not chewing your food enough Dehydration GastroIntestinal Dysbiosis, especially SIBO where too many bacteria grow in the small intestine (they are mainly meant to be in the large intestine, even ‘good’ bacteria can cause issues if too many are in the small intestine.) Food intolerances (although these maybe a symptom of gut issues, rather than cause)   Frequent Antibiotics Alcohol (along with any other downsides, alcohol kills all bacteria, good and bad, on contact, similar to an antibiotic, which is why it’s used as a disinfectant) Lack of exercise Smoking Lack of or Poor Quality Sleep Chronic Stress Is There a Test for Digestion?There are a variety of tests that can be taken to check your digestive health. Some of these include:Fecal Occult Blood Test, Stool Culture, Barium Meal, drink or enema, CT, CAT or MRI scans, Defecography, Ultrasound, Colonoscopy, Endoscopic procedures and more. Consult your physician if you are worried about symptoms you are experiencing and they will help you to determine the best course of action.Because your gut microbiome is so important to your overall health [2], it’s important to understand what’s going on, and how your gut is balanced.Microbiome tests can be conducted by your physician or at home. Although some tests use blood or saliva, the most comprehensive microbiome tests will require a stool sample.Your stool sample will be sent to a laboratory to be tested where they will analyze the balance of microbes in your gastrointestinal system.This will help you and your doctor understand if there is an imbalance of microbes that is causing problems to your overall health.The Top 8 Ways to Improve Your Gut Health:Here’s the top 8 changes you can make to your lifestyle to help support and improve your gastrointestinal health: Eat a clean, diverse organic diet full of nutrient dense foods. Processed (especially fast) foods cause harm to your gut microbiome [3]. Be sure to include prebiotic foods (a type of fiber that isn’t digested) [4] such as oats, bananas, chicory and asparagus, because they promote the growth of certain types of good bacteria. Note: prebiotic foods can make issues worse IF you have too many bacteria in the small intestine. If you suspect this is the case, get the advice of a professional who specializes in gut health. Eat in a relaxed state, where you will naturally eat slower and chew your food properly. Being in a stressed state is sometimes necessary, but while you are in a stressed state, digestion slows down significantly, and you produce much less of the digestive juices you need to sanitize and process your food, like saliva, stomach acid and bile. You’ll also tend to eat more quickly and not chew enough. So make sure you calm down before you start eating, even if it’s just taking a few deep breaths. This is where the tradition of saying grace comes from: even if you have no religious leanings, you may want to consider it as a way of refocusing your mind to be in a less stressed state, which will help you digest better!And once you’re relaxed, it will be easier to chew your food enough, sometimes as much as 30 times before swallowing, which helps your body to more easily digest the food and absorb as many nutrients as possible [5]. Find out if you’re intolerant to certain foods. Eating foods you're intolerant to will affect your digestive health, resulting in bloating, gas, diarrhea and more [6]. Speak to your physician to organize a skin prick or blood test.Another way to narrow down your intolerances is to record the foods you’ve eaten - be sure to write down how these foods make you feel. Only change one or two things at a time, so that you can easily identify any changes.If you suspect a food, many recommend an elimination diet, where you remove the suspected food for around a week, and then introduce it again, seeing if you notice any symptoms when you add it back into your diet. Limit alcohol consumption. Alcohol can induce changes to the microbiome in the gastrointestinal tract, (due to its ability to kill bacteria, but not kill and often feed yeasts such as candida) which can lead to increased oxidative stress amongst other problems [7]. Reduce your stress. Chronic Stress can seriously affect your guts microbiome composition [8].Occasional Stress is healthy, but ongoing stress is not. If you struggle to relax, there are many ways to lower your stress levels, such as meditation. You can also try supplementing with our Serenity Anti-Stress Support or 5 HTP products. Improve your sleep. Poor sleep and sleep deprivation can affect your microbiome diversity [9]. Our Sleep Aid Plus can also help, and read the page for more info on how to Sleep better naturally. LINK! Drink more water and stay hydrated. This is another way to encourage microbiome diversity [10], and staying hydrated is essential to your overall health, as well as reducing the likelihood of constipation.   Take a digestive enzyme supplement that is also packed full of live “good” bacteria that can help to boost your digestion and gut microbiome: Protease. Responsible for breaking down proteins into amino acids. In a study on piglets, protease supplementation increased nutrient utilization efficiency and growth performance [11].Lipase. Responsible for the breakdown of Fat into fatty acids, ready for your cells to absorb. Lipase is a very important ingredient in a digestive enzyme blend, because many of us struggle to digest the amount of fat we eat.Lactobacillus acidophilus. Often referred to as L. acidophilus, lactobacillus acidophilus is a variety of bacteria that can be found in the intestines which is essential for human health [12].Lactobacillus casei.  A powerful probiotic that is extremely beneficial to the digestive system. A study on patients with chronic constipation found that a probiotic drink containing L.casei helped to see improvements alongside other therapy [13].Lactobacillus plantarum. Found mainly in fermented plant foods such as pickles, L. plantarum has been shown to have anti-inflammatory, blood sugar regulatory, anti-weight gain and antioxidant properties. Studies have shown L. plantarum to reduce the incidence of abdominal pain, loose stools and diarrhea associated with antibiotics [14].Bromelain. Found in pineapples - bromelain is an enzyme that digests protein and has powerful anti-inflammatory properties. It also has pain killing properties [15].Papain. Found in raw papaya plant fruit, papain is a proteolytic enzyme that helps to break down proteins. It has a whole host of benefits, from helping to maintain digestive tract physiology [16], to reducing pain, inflammation and helping to heal wounds quicker.Our digestive enzyme probiotic supplement includes Makzyme-Pro™ Enzyme Blend, which is a formula made up of Protease, Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum. This powerful combination helps to improve your gut health and assists your body in breaking down foods more effectively so that nutrients can be absorbed more efficiently.In addition to Makzyme-Pro™ we have added Bromelain, Papain, Lipase, Lactase and Alpha Galactosidase to further enhance the power and effectiveness of the supplement.We understand that it’s not always easy, nor practical to implement a variety of lifestyle changes - especially all at once.We’d advise that you make as many of the changes listed further up this page as possible, but to do so 1 or 2 at a time, make sure they stick and then move onto more.In the meantime, you can support your body with essential good bacteria it needs to maintain a healthy gut microbiome.Here at Feel younger, we believe in providing strong doses at reasonable prices. Our Digestive Enzyme Probiotic Blend provides a strong and healthy dose of digestive enzymes, as well as billions of live bacteria, and will cost you no more than $27, with discounts available on multiple bottle and subscription purchases.How Do You Take Feel Younger® Digestive Enzyme Probiotic Blend?Take one capsule twice a day.For best results take 20-30 minutes before a meal.Any Cautions?In very rare cases, the combination of enzymes and probiotics in this supplement can cause constipation, nausea, cramps, diarrhea, throat irritation, and women could experience heavier menstrual bleeding Scientific References https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1564-7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290017/ https://pubmed.ncbi.nlm.nih.gov/30945554/ https://pubmed.ncbi.nlm.nih.gov/18215222/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219460/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767923/ https://pubmed.ncbi.nlm.nih.gov/26695747/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213601/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779243/ https://academic.oup.com/jn/article/152/1/171/6395031 https://www.sciencedirect.com/science/article/pii/S2405654515300354 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519286/ https://pubmed.ncbi.nlm.nih.gov/14631461/ https://pubmed.ncbi.nlm.nih.gov/9815476/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/ https://pubmed.ncbi.nlm.nih.gov/23524622/

Would you like… Antiviral Immune System Support Antioxidant Support Inflammation Support Improved Heart Health A Nutritional Boost If so, you may want to give our Elderberry Immune Support a try. Elderberry is also believed to have many other benefits, some of which are: Helping to treat urinary tract & bladder infections and cystitis Providing allergy relief Improving digestive health Improving blood sugar control What is Elderberry and where does it come from?Elderberry comes from the Sambucus tree, which is a plant in the Adoxaceae family.Although Elderberry grows across North Africa, Asia and America, it is native to Europe and the most common variety is the black elderberry (Sambucus nigra) or European elder [1].Elderberry hosts an impressive nutritional profile. The fruits are dense in vitamins and minerals such as carotenoids (provitamin a), vitamin c, phosphorus, iron potassium, calcium and more [2].Elderberry flowers, berries and leaves also contain lots of antioxidants (anthocyanins, phenolics & flavonoids) that can help balance the immune system and lower oxidative stress [3].John Evelyn (a british researcher in the 17th century) said: “If the medicinal properties of its leaves, bark and berries (elderberry) were fully known, I cannot tell what our country man could ail for which he might not fetch a remedy, either for sickness or wounds.”Its use has been widespread throughout history, with elderberry based medication records dating as far back as Ancient Egypt, it’s been used to help treat fevers, flus, colds, cuts, burns and toothache.How can Elderberry support you?Elderberry’s impressive nutritional profile can provide many benefits, such as: Immune system support due to the antioxidants found in the leaves, berries and flowers [4] Helping to reduce inflammation due to their flavonoid content [5] Improving heart health by lowering liver cholesterol, blood triglycerides, fat build up, blood pressure and blood sugar level control [6] People mainly use Elderberry to:Boost Their Immune SystemAir traveling puts the immune system under enormous stress. Those who fly frequently (and especially long distance) are more susceptible to the common cold.A double-blind placebo-controlled study on air travelers showed that Elderberry supplementation reduced cold symptoms and duration [7].Another double-blind placebo-controlled study tested the efficacy of 15 ml of Elderberry extract syrup, given 4 times a day to 60 patients who were suffering from influenza-like symptoms.The control group who did not take elderberry extract took 7-8 days to improve, compared to 2-4 days for those who took the syrup [8]A different study on elderberry extract and the reduction of influenza b symptoms showed that those given the elderberry extract recovered in 2-3 days, compared to at least 6 days in the placebo group [9].A study on rats showed elderberry polyphenols supported immune defense by increasing the number of white blood cells [10].Promote Heart HealthElderberry may improve some markers of blood vessels and heart health.Diets high in flavonoids such as anthocyanins (which are found in elderberries) have been shown to reduce the risk of heart problems [11].Numerous studies have shown that elderberry juice can help reduce the total level of fat in the blood, while decreasing cholesterol [12].Type-2 diabetes is one of the major contributors to heart and vascular problems, so blood sugar management is imperative to eliminate the risk of contracting these problems.Various studies on mice have shown that elderberries can help improve blood sugar levels while increasing insulin secretion [13].Why Try Feel Younger® Elderberry Immune Support, 600mg Elderberry Fruit Extract?Our Elderberry Immune Support capsules are high quality, high purity, all natural, sugar free, lactose free, corn free, vegetarian and vegan friendly and contain no nasty binders.Here at Feel Younger, we believe in providing strong doses at reasonable prices. How do you take Feel Younger® Elderberry Immune Support, 600mg Elderberry Fruit Extract?Take one capsule twice a day with water, preferably 20-30 minutes before a meal.If you want to take Elderberry Immune Support to help relieve cold or flu symptoms, follow the above instructions and take at the first sign of symptoms.Any cautions?In very rare cases, nausea or diarrhea may occur.ALWAYS consult a healthcare professional before taking any new supplements. Scientific References https://pubmed.ncbi.nlm.nih.gov/24409980/ https://www.researchgate.net/publication/27771618 https://www.sciencedirect.com/science/article/abs/pii/S0963996905000943 https://www.sciencedirect.com/science/article/abs/pii/S0963996905000943 https://pubmed.ncbi.nlm.nih.gov/31288163/ https://pubmed.ncbi.nlm.nih.gov/27417664/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848651/ https://pubmed.ncbi.nlm.nih.gov/15080016/ https://pubmed.ncbi.nlm.nih.gov/9395631/ https://www.rombio.eu/rbl1vol16/17%20Badescu.pdf https://pubmed.ncbi.nlm.nih.gov/23953879/ https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.2729 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297648/