Canada RNA Biochemical

Lumbrokinase Enzyme Supplement Boluoke® is a supplement containing purified lumbrokinase, a group of enzymes derived from Lumbricus rubellus. Manufactured in Canada by Canada RNA Biochemical Inc., Boluoke® is standardised for enzymatic activity and supplied in acid-resistant capsules designed to protect the enzyme as it passes through the stomach. This travel-size bottle contains 30 capsules for convenient use. What Is Lumbrokinase? Lumbrokinase refers to a group of proteolytic (protein-digesting) enzymes extracted from earthworms. These enzymes have been researched in Asia for several decades and are standardised in Boluoke® to consistent enzymatic activity levels. Each capsule contains: Proprietary Lumbrokinase – 300,000 LKU(≥1.6 million tPA activity units) Each batch is manufactured to consistent enzymatic strength specifications. Product Features • 300,000 LKU per capsule• ≥1.6 million tPA activity units per capsule• Acid-resistant hypromellose capsules• Free from dairy, gluten, corn and soy allergens• Manufactured in Canada• Travel size – 30 capsules Suggested Use Take 1–2 capsules one to three times daily on an empty stomach, or as directed by a healthcare professional. Capsules should be swallowed whole. The acid-resistant capsule is designed to help protect the enzyme until it reaches the small intestine. Ingredients Active Ingredient:Lumbrokinase (proprietary) Other Ingredients:Acid-resistant hypromellose capsule, microcrystalline cellulose.   Important Information Food supplement. Do not exceed the stated recommended dose. Consult a healthcare professional before use if you: • Are pregnant or breastfeeding• Are taking anticoagulants, antiplatelet agents, aspirin, NSAIDs or any prescription medications• Have a bleeding tendency• Are taking any medications• Have a known allergy to lumbrokinase or earthworms Lumbrokinase may influence platelet function. Individuals taking prescription medications should consult a healthcare professional before use. Do not use if you have: • Recent surgery or are scheduled for surgery• Undergone or are scheduled for lumbar puncture or arterial puncture• Recent trauma• A high-risk aneurysm• Active internal bleeding• Gastrointestinal ulceration• Any diagnosed bleeding disorder Discontinue use and seek immediate medical advice if unusual bleeding, bruising, or adverse reactions occur. Keep out of reach of children.Store in a cool, dry place. This product is not intended to diagnose, treat, cure or prevent any disease. Boluoke FAQs Can Boluoke® be taken alongside blood-thinning medication? If you are taking anticoagulants, antiplatelet medicines, aspirin, NSAIDs or any prescription medication, you must consult your GP or healthcare professional before using Boluoke®. Lumbrokinase may influence platelet function, therefore professional supervision is advised when combining with any medication that affects blood clotting.  Can the content of Boluoke® capsules be emptied out and taken without the capsules? Boluoke® capsules are acid-resistant and designed to help protect the enzyme as it passes through the stomach. The capsule helps ensure delivery to the small intestine. For best results, capsules should be swallowed whole on an empty stomach. Opening capsules is not recommended unless advised by a healthcare professional. How long before surgery should patient stop taking Boluoke®? If you are scheduled for surgery or a medical procedure, consult your doctor. As a precaution, many healthcare professionals advise discontinuing use approximately one week before surgery, unless otherwise directed. Do not resume use after surgery without medical advice. Can Boluoke® be safely taken with anti-platelet agents? Lumbrokinase may influence platelet function. If you are using prescription antiplatelet medication, you must consult a healthcare professional before taking Boluoke®. Can Boluoke® be safely taken with aspirin? Please consult a doctor before taking Boluoke® if you are on any medications. Boluoke® can affect platelet aggregation, so speak with your GP or pharmacist before using this product. Can Boluoke® be used on pregnant women? Boluoke® is not recommended during pregnancy or breastfeeding. If you are pregnant, trying to conceive consult your GP before use. What are the contra-indications for taking Boluoke®? Contra-indications for Boluoke® are: allergy to lumbrokinase or earthworm; recent surgery; pre-surgery; lumbar puncture or arterial puncture; trauma; high risk aneurysm; active internal bleeding or GI ulceration; any other bleeding disorders/tendencies. People who are taking any medications should consult their physicians before taking Boluoke®. Does Boluoke® have any side effects? Lumbrokinase has been used in traditional practice for many years. In published clinical observations outside the UK, mild reactions have occasionally been reported, including: • Skin itching• Mild rash• Digestive discomfort such as nausea or diarrhoea If you experience unusual bruising, bleeding or adverse reactions, discontinue use immediately and seek medical advice.  Can Boluoke® be taken with other enzyme products? It is generally NOT recommended to take Boluoke® alongside other proteolytic enzyme supplements unless advised by a healthcare professional. If required, take Boluoke® on an empty stomach and separate other enzyme supplements by at least 30 minutes. What is the suggested protocol for taking Boluoke®? The suggested dosage is 1-2 capsules one to three times daily on an empty stomach, or as directed by a health care practitioner.