Latest Advancements And Cutting Edge Solutions (38)

About: Developed by William Davis, MD. Author of "Wheat Belly" and "Super Gut". Lactobacillus reuteri supports GI health, bowel function and immune function* Can be used to make William Davis, MD. Superfood L. reuteri yogurt/cultured dairy. MyReuteri 10 billion standard dosage is suitable as a daily probiotic or for use to make cultured dairy. MyReuteri 20 billion is ideal for those seeking a higher-potency dosage, and can also be used to make cultured dairy. MyReuteri Formulation Based on the science of the Gut-Skin Axis, doctor-developed MyReuteri is formulated with LRDR L. Reuteri and FOS. Lactobacillus reuteri LRDR™  Our proprietary LRDR™ strain of Lactobacillus reuteri provides an important microbe that the great majority are missing in their gut. This microbe not only resides in the colon but also the upper GI tract. Daily incorporation of L. reuteri LRDR™  helps you support gut health and gut balance.* FOS (Fructooligosaccharides) MyReuteri includes the prebiotic fiber FOS which serves as food for the Lactobacillus reuteri microbes.  The FOS in MyReuteri supports L. Reuteri cultured daily fermentation (aka “L. reuteri yogurt”) for home yogurt-making. Note: *These statements have not been evaluated by the Food and Drug Administration.  This product is NOT recommended for use in pregnancy.   These products are designed to supplement a healthy diet and lifestyle, and are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare professional before using any dietary supplement, particularly if you are pregnant, breastfeeding, have a medical condition, or are taking medication. Do not exceed the recommended daily dose. Keep out of the reach of children. If any adverse reactions occur, discontinue use and consult a healthcare provider.  MyReuteri FAQs by Oxiceutics Product Information What is in MyReuteri? MyReuteri contains high counts of the important gastrointestinal microbe, Lactobacillus reuteri, that Dr. Davis has been talking about, making yogurt with, and studying in humans and animals. Because L. reuteri, as well as many other bacterial species, is susceptible to common antibiotics, many have lost this microbe and thereby all of its potential benefits. MyReuteri is Oxicuetics way of restoring this important microbe. Does MyReuteri have to be refrigerated? While it does not hurt to refrigerate MyReuteri, there is no need to. It is helpful, however, to store in a relatively cool area out of direct sunlight and, of course, with the cap on, as want the microbes to avoid exposure to moisture. My product arrived hot. Is the probiotic still good? The probiotic strains in MyReuteri can start to die off around 110°F (43°C). MyReuteri is stored at room temperature. So even if you received the product warm, it is still good. Should I take MyReuteri with food or without food? And any specific time of day? MyReuteri can be taken with food or without, as it does not impact significantly on the number of surviving microbes. The only precaution to take is to not consume theprobiotic capsules of MyReuteri while sipping or eating a food that is very hot, e.g.,coffee, tea, hot soups, as the heat can kill the microbes and may reduce potentialbenefits. Also, the only issue with time of day is that some people feel a little sleepy if taken early in the day. If this happens to you, simply shift the time you take MyReuteri to evening or bedtime. Why are there such high numbers of microbes in MyReuteri? Oxiceutics' experience has been that, in general, greater numbers of microbes with probiotic properties provide greater effects than smaller numbers. After all, the human gastrointestinal microbiome numbers around 100 trillion. It may reasonably therefore require tens to hundreds of billions to generate meaningful effects. Because of the effort and expense of generating such “dose-response” observations, the understanding of this phenomenon in the microbiome science world is limited. Until we gain a better understanding, we include counts of microbes that we believe yield significant benefits. Why do we need to add inulin in making MyReuteri yogurt? Inulin, a prebiotic fibre in common foods, supports Lactobacillus reuteri in lactose digestion. If you have a reaction to inulin yogurt, consult your doctor. Can I take MyReuteri in combination with other nutritional supplements? Yes, but with some exceptions. Because MyReuteri is a living microbe, we avoid taking it with anything that has antibiotic effects. This includes any supplement containing iodine, any supplement you may be taking to manage intestinal dysbiosis, small intestinal bacterial overgrowth (SIBO), or fungal overgrowth. This includes supplements such as berberine, curcumin (turmeric), and essential oils taken orally. Other supplements such as vitamin D, fish oil, magnesium and many others are perfectly compatible. Is it safe to take MyReuteri with other probiotics? Yes, it is perfectly safe to combine MyReuteri with other probiotics including with Gut to Glow. I am experiencing some nausea and stomach upset with MyReuteri. What does this mean and should I stop taking it? This is a common experience with any probiotic and is due to antagonistic effects that L.reuteri and other probiotic species introduce against unhealthy microbes in thegastrointestinal tract. One way to deal with this is to reduce the dose, e.g., reduce from two capsules per day to one capsule per day or even one capsule every-other-day. You can also take your dose with food to disperse the bacteria. Should you continue to experience difficulty, consult your doctor but ask specifically about the possibility that you have small intestinal bacterial overgrowth, SIBO, i.e., unhealthy bacterial species that have colonised your stomach and small intestine. When a beneficial microbe such as L. reuteri is introduced, unhealthy bacterial species begin to die and this can yield some unpleasant effects. Your doctor may have additional steps you can take that can help you better tolerate MyReuteri, as well as other probiotics and fermented foods, once this phenomenon is addressed. Should I anticipate side-effects from taking MyReuteri? Beyond the nausea, bloating, and diarrhea that can occur when initiating any probiotic, we know of no side effects of supplementing MyReuteri. You may have heard Dr. Davis say that nearly all hunter-gatherer humans and mammals have this microbe–it’s most modern humans that have lost this microbe and thereby its potential benefits. Restoring factors that should have been part of the human experience all along is therefore typically not associated with adverse effects. Why have modern people lost L. reuteri, the microbial species contained in MyReuteri? Modern people have been overexposed to antibiotics such as amoxicillin, cefazolin, and gentamicin. L. reuteri, the microbial species contained in MyReuteri, is very susceptible to common antibiotics and has therefore been eradicated from the gastrointestinal microbiomes of most people. There may be other factors that contribute to its disappearance such as herbicide and pesticide residues in food, food additives with antimicrobial properties such as food preservatives and emulsifying (mixing) agents, and various pharmaceuticals. Even German microbiologist, Dr. Gerhard Reuter, who initially discovered this microbe in the breastmilk of a breastfeeding mother in 1962 made the observation over his subsequent 40-year academic career, that it became harder and harder to recover this organism from breastmilk, stool, and other body locations over this time period. More recent analyses have corroborated Dr. Reuter’s observation: L. reuteri has been lost by many people. Why do you recommend that we not take MyReuteri during pregnancy? MyReuteri provides the microbe, L. reuteri, at relatively high counts, as does Gut toGlow. While all mammals, including humans, are meant to have this beneficial microbe as part of their gastrointestinal microbiome, we do not know if the high counts provided by these products (or as the yogurt that you ferment from these products) is safe in the setting of pregnancy. Recall that women can be given oxytocin intravenously to provoke uterine contraction at term pregnancy, causing the baby to be delivered. (L. reuteri has been shown in animal studies to increase oxytocin.) We therefore do not know if it is safe to consume higher intakes of L. reuteri in pregnant females. Can I make “yogurt” with MyReuteri? Yes, absolutely. You can use the microbes in MyReuteri as a starter for yogurt making.  Of course, it is not really yogurt in the conventional sense, but a fermented dairy product that looks and smells like yogurt. In our analyses of the yogurts made from MyReuteri, we obtain approximately 300 billion CFUs (microbial counts) per ½-cup serving. Yogurt made from MyReuteri will be more sour than conventional yogurt because the extended fermentation method we use to achieve high bacterial counts also converts nearly all the lactose to lactic acid, accounting for the acidic or sour flavour. Feel free to add blueberries, strawberries, chia seeds, sunflower seeds, and healthy non-caloric sweeteners such as monk fruit, allulose, or stevia to soften the sourness. Why does the powder in the MyReuteri capsule sometimes appear clumpy and is it still okay?  In some instances, excessive humidity can cause the powder inside the capsule to clump together, however, formulation remains viable and effective.  If using to make yogurt, use a spoon to gently break up the powder before mixing.  Be sure to keep the bottle tightly closed and keep the desiccant moisture-absorbing pack in the bottle, and store in a cool dry place or refrigerator.   Why choose MyReuteri 10 billion standard dosage?  MyReuteri 10 billion standard dosage is suitable as a daily probiotic or for use to make cultured dairy.   Why do some people prefer MyReuteri 20 billion double-strength?   MyReuteri 20 billion is ideal for those seeking a higher-potency dosage, and can also be used to make cultured dairy.   How does MyReuteri 10 billion compare to other L. reuteri products?  Only MyReuteri is the authentic L. Reuteri by Dr. Davis and designed for use as both an oral probiotic and for use as a starter culture.  Because it is made in the USA, MyReuteri avoids the temperature variations and carbon foodprint of ocean shipping.  Is MyReuteri 20 billion a good value at $60?    MyReuteri 20 billion provides 50% additional LRDR L. reuteri for only 25% more cost, an excellent value on a per CFU basis.  Why does MyReuteri include magnesium stearate?  Safe and widely used in supplements, medicines and foods, a small amount of magnesium stearate is included to facilitate consistency in the production process. 

About: Developed by William Davis, MD. Author of "Wheat Belly" and "Super Gut". Lactobacillus reuteri supports GI health, bowel function and immune function* Can be used to make William Davis, MD. Superfood L. reuteri yogurt/cultured dairy. MyReuteri 10 billion standard dosage is suitable as a daily probiotic or for use to make cultured dairy. MyReuteri 20 billion is ideal for those seeking a higher-potency dosage, and can also be used to make cultured dairy. MyReuteri Formulation Based on the science of the Gut-Skin Axis, doctor-developed MyReuteri is formulated with LRDR L. Reuteri and FOS. Lactobacillus reuteri LRDR™  Our proprietary LRDR™ strain of Lactobacillus reuteri provides an important microbe that the great majority are missing in their gut. This microbe not only resides in the colon but also the upper GI tract. Daily incorporation of L. reuteri LRDR™  helps you support gut health and gut balance.* FOS (Fructooligosaccharides) MyReuteri includes the prebiotic fiber FOS which serves as food for the Lactobacillus reuteri microbes.  The FOS in MyReuteri supports L. Reuteri cultured daily fermentation (aka “L. reuteri yogurt”) for home yogurt-making. Note: *These statements have not been evaluated by the Food and Drug Administration.  This product is NOT recommended for use in pregnancy.   These products are designed to supplement a healthy diet and lifestyle, and are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare professional before using any dietary supplement, particularly if you are pregnant, breastfeeding, have a medical condition, or are taking medication. Do not exceed the recommended daily dose. Keep out of the reach of children. If any adverse reactions occur, discontinue use and consult a healthcare provider.  MyReuteri FAQs by Oxiceutics Product Information What is in MyReuteri? MyReuteri contains high counts of the important gastrointestinal microbe, Lactobacillus reuteri, that Dr. Davis has been talking about, making yogurt with, and studying in humans and animals. Because L. reuteri, as well as many other bacterial species, is susceptible to common antibiotics, many have lost this microbe and thereby all of its potential benefits. MyReuteri is our way of restoring this important microbe. Does MyReuteri have to be refrigerated? While it does not hurt to refrigerate MyReuteri, there is no need to. It is helpful, however, to store in a relatively cool area out of direct sunlight and, of course, with the cap on, as want the microbes to avoid exposure to moisture. My product arrived hot. Is the probiotic still good? The probiotic strains in MyReuteri can start to die off around 110°F (43°C). MyReuteri is stored at room temperature. So even if you received the product warm, it is still good. Should I take MyReuteri with food or without food? And any specific time of day? MyReuteri can be taken with food or without, as it does not impact significantly on the number of surviving microbes. The only precaution to take is to not consume theprobiotic capsules of MyReuteri while sipping or eating a food that is very hot, e.g.,coffee, tea, hot soups, as the heat can kill the microbes and may reduce potentialbenefits. Also, the only issue with time of day is that some people feel a little sleepy if taken early in the day. If this happens to you, simply shift the time you take MyReuteri to evening or bedtime. Why are there such high numbers of microbes in MyReuteri? Oxiceutics experience has been that, in general, greater numbers of microbes with probiotic properties provide greater effects than smaller numbers. After all, the human gastrointestinal microbiome numbers around 100 trillion. It may reasonably therefore require tens to hundreds of billions to generate meaningful effects. Because of the effort and expense of generating such “dose-response” observations, the understanding of this phenomenon in the microbiome science world is limited. Until we gain a better understanding, we include counts of microbes that we believe yield significant benefits. Why do we need to add inulin in making MyReuteri yogurt? Inulin, a prebiotic fiber in common foods, supports Lactobacillus reuteri in lactose digestion. If you have a reaction to inulin yogurt, consult your doctor. Can I take MyReuteri in combination with other nutritional supplements? Yes, but with some exceptions. Because MyReuteri is a living microbe, we avoid taking it with anything that has antibiotic effects. This includes any supplement containing iodine, any supplement you may be taking to manage intestinal dysbiosis, small intestinal bacterial overgrowth (SIBO), or fungal overgrowth. This includes supplements such as berberine, curcumin (turmeric), and essential oils taken orally. Other supplements such as vitamin D, fish oil, magnesium and many others are perfectly compatible. Is it safe to take MyReuteri with other probiotics? Yes, it is perfectly safe to combine MyReuteri with other probiotics including with Gut to Glow. I am experiencing some nausea and stomach upset with MyReuteri. What doesthis mean and should I stop taking it? This is a common experience with any probiotic and is due to antagonistic effects that L.reuteri and other probiotic species introduce against unhealthy microbes in thegastrointestinal tract. One way to deal with this is to reduce the dose, e.g., reduce from two capsules per day to one capsule per day or even one capsule every-other-day. You can also take your dose with food to disperse the bacteria. Should you continue to experience difficulty, consult your doctor but ask specifically about the possibility that you have small intestinal bacterial overgrowth, SIBO, i.e., unhealthy bacterial species that have colonized your stomach and small intestine. When a beneficial microbe such as L. reuteri is introduced, unhealthy bacterial species begin to die and this can yield some unpleasant effects. Your doctor may have additional steps you can take that can help you better tolerate MyReuteri, as well as other probiotics and fermented foods, once this phenomenon is addressed. Should I anticipate side-effects from taking MyReuteri? Beyond the nausea, bloating, and diarrhea that can occur when initiating any probiotic, we know of no side effects of supplementing MyReuteri. You may have heard Dr. Davis say that nearly all hunter-gatherer humans and mammals have this microbe–it’s most modern humans that have lost this microbe and thereby its potential benefits. Restoring factors that should have been part of the human experience all along is therefore typically not associated with adverse effects. Why have modern people lost L. reuteri, the microbial species contained inMyReuteri? Modern people have been overexposed to antibiotics such as amoxicillin, cefazolin, and gentamicin. L. reuteri, the microbial species contained in MyReuteri, is very susceptible to common antibiotics and has therefore been eradicated from the gastrointestinal microbiomes of most people. There may be other factors that contribute to its disappearance such as herbicide and pesticide residues in food, food additives with antimicrobial properties such as food preservatives and emulsifying (mixing) agents, and various pharmaceuticals. Even German microbiologist, Dr. Gerhard Reuter, who initially discovered this microbe in the breastmilk of a breastfeeding mother in 1962 made the observation over his subsequent 40-year academic career, that it became harder and harder to recover this organism from breastmilk, stool, and other body locations over this time period. More recent analyses have corroborated Dr. Reuter’s observation: L. reuteri has been lost by many people. Why do you recommend that we not take MyReuteri during pregnancy? MyReuteri provides the microbe, L. reuteri, at relatively high counts, as does Gut toGlow. While all mammals, including humans, are meant to have this beneficial microbe as part of their gastrointestinal microbiome, we do not know if the high counts provided by these products (or as the yogurt that you ferment from these products) is safe in the setting of pregnancy. Recall that women can be given oxytocin intravenously to provoke uterine contraction at term pregnancy, causing the baby to be delivered. (L. reuteri has been shown in animal studies to increase oxytocin.) We therefore do not know if it is safe to consume higher intakes of L. reuteri in pregnant females. Can I make “yogurt” with MyReuteri? Yes, absolutely. You can use the microbes in MyReuteri as a starter for yogurt making.  Of course, it is not really yogurt in the conventional sense, but a fermented dairy product that looks and smells like yogurt. In our analyses of the yogurts made from MyReuteri, we obtain approximately 300 billion CFUs (microbial counts) per ½-cup serving. Yogurt made from MyReuteri will be more sour than conventional yogurt because the extended fermentation method we use to achieve high bacterial counts also converts nearly all the lactose to lactic acid, accounting for the acidic or sour flavor. Feel free to add blueberries, strawberries, chia seeds, sunflower seeds, and healthy non-caloric sweeteners such as monk fruit, allulose, or stevia to soften the sourness. Why does the powder in the MyReuteri capsule sometimes appear clumpy and is it still okay?  In some instances, excessive humidity can cause the powder inside the capsule to clump together, however, formulation remains viable and effective.  If using to make yogurt, use a spoon to gently break up the powder before mixing.  Be sure to keep the bottle tightly closed and keep the desiccant moisture-absorbing pack in the bottle, and store in a cool dry place or refrigerator.   Why choose MyReuteri 10 billion standard dosage?  MyReuteri 10 billion standard dosage is suitable as a daily probiotic or for use to make cultured dairy.   Why do some people prefer MyReuteri 20 billion double-strength?   MyReuteri 20 billion is ideal for those seeking a higher-potency dosage, and can also be used to make cultured dairy.   How does MyReuteri 10 billion compare to other L. reuteri products?  Only MyReuteri is the authentic L. Reuteri by Dr. Davis and designed for use as both an oral probiotic and for use as a starter culture.  Because it is made in the USA, MyReuteri avoids the temperature variations and carbon foodprint of ocean shipping.  Is MyReuteri 20 billion a good value at $60?    MyReuteri 20 billion provides 50% additional LRDR L. reuteri for only 25% more cost, an excellent value on a per CFU basis.  Why does MyReuteri include magnesium stearate?  Safe and widely used in supplements, medicines and foods, a small amount of magnesium stearate is included to facilitate consistency in the production process. 

Stem-Kine 60 Capsules (Aiden Products) Stem-Kine is a clinically proven proprietary stem cell supplement that stimulates your body to double the release of circulating stem cells, revitalizing your health, wellness, and regenerative capabilities.1,2 Proven in Human Studies Other supplements have studies on fruit flies or in petri dishes. We have demonstrated Stem-Kine’s potency in human clinical trials, the only way to truly demonstrate whether or not a supplement actually works! The links below take you to the free peer-reviewed journal articles that contain the human research behind Stem-Kine! Clinical Trial #1 Clinical Trial #2 Research on Stem-Kine 1. Circulating endothelial progenitor cells: a new approach to anti-aging medicine? 2. Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects How Does Stem-Kine Work? Stem-Kine’s powerful ingredients contain a proprietary, heat-treated extract of Lactobacillus Fermentum and the powerful antioxidants astragalus root, goji berry, and green tea. This cell wall extract gives Stem-Kine its “fertilizer effect” and releases stem cells into the bloodstream & protects those cells from oxidative stress. Supplemental ingredients include beta-1,3-glucan, vitamin D3, and ellagic acid to further protect stem cells from oxidative stress.   Lactobacillus Fermentum Containing patented and patent-pending fermented blends of astragalus root, goji berry, and green tea, our proprietary ingredient nourishes the bone marrow to release more stem cells into the blood stream. Once these stem cells are in circulation, they can hone to sources of injury within the body and begin the repair process.   Beta 1,3 Glucan A natural immune booster, beta glucans have been shown in multiple research studies to trigger a cascade of events that help regulate the immune system, making it stronger and more efficient. Beta glucans are also extremely important for heart health. A recent research study showed that people who ingested more beta glucans, had a significantly greater reduction of total cholesterol and low density lipoprotein (LDL).   Ellagic Acid Sourced from nature’s powerful antioxidant, pomegranate, ellagic acid harbors a powerful chemoprotective effect by reducing oxidative stress. This ingredient helps to protect your stem cells from free radicals.   Vitamin D3 For more than a century, scientists have recognized that Vitamin D3 is involved in bone health. Not only that, it is paramount in immune support & low levels of Vitamin D3 are linked to depression, back pain, cancer, impaired immunity, and much more. How to take?   Take 2-4 capsules per day as part of a healthy diet. Can be taken with or without food.   Loading dose = 2 servings AM/PM (4 capsules daily)   Maintenance dose = 1 servings AM (2 capsules daily) Overview: We suggest taking a double dose for the first bottle (4 capsules daily) to optimize the release of stem cells over the first 2-week period of time. Continuing with a maintenance dose of 2 capsules/day will help to nourish these stem cells and protect them from oxidative stress. Responses to Stem-Kine may differ, and some individuals may want to continue taking 4 capsules daily to maintain optimal effects. As with any new supplement, it is advised to consult your physician before using. If you are using any prescription or over-the-counter medicines, are unaware of your current medical condition, or have any pre-existing medical condition(s), consult with your physician before using this product. There are no known side effects from taking Stem-Kine.

One Molecule. Hundreds Of Benefits. Over 2000 Scientific Studies.It’s not too good to be true—Molecular Hydrogen is the energy-boosting, brain-enhancing, performance-improving, pro-longevity antioxidant, anti-inflammatory, and anti-wrinkle supplement only researchers have heard of.Say Hello To HydrogenThe molecular answer to modern disease. You know the numbers… Every 33 seconds, someone in the United States dies from cardiovascular disease [1]. Every 52 seconds, someone dies from cancer [2].Statistically, one out of every three of your friends has metabolic syndrome and a higher risk of heart disease, diabetes, and stroke [3].The solution?One of the smallest compounds on Earth.Over 2000 studies prove molecular hydrogen’s powerful ability to support the underlying causes of modern disease.Benefit From... Sharper brain function [4] Sustained energy [5] Balanced body composition [6] Better Skin [7] Boosted metabolism [8] Improved immune function [9] Faster recovery [10] Powerful anti-aging [11] Potent mitochondrial protection [12] The vitality to do what you love Most Antioxidants Have A Dark Side...Generally, antioxidants do a lot of good. Research shows they fight aging, support our immune system, and help us avoid heart disease and cancer (13).But they also have a dark side.Why?Your body does best with balance. The right amount of stress—even oxidative stress—is a crucial trigger for powerful endogenous antioxidants like superoxide dismutase, catalase, and glutathione peroxidase.Most supplemental antioxidants disturb this delicate balance.But Molecular Hydrogen isn't most antioxidants.It acts as a master antioxidant by stimulating your body’s own internal defense system—your best source of optimized energy, performance, and recovery [14,15].Molecular Hydrogen Promotes Health In Three Primary Ways: Unique antioxidant action: Directly and indirectly protects cells, proteins, and DNA from oxidative damage while elegantly influencing intracellular communication Powerful anti-inflammatory: Reduces innate immune activation and promotes balance of pro- and anti-inflammatory cytokines at the genetic level (16, 17) Dynamic apoptotic regulation: Adaptively balances programmed cell death and degradation—protects normal cells and may inhibit proliferation of malignant cells (18)     Blood Sugar Balance And Beauty With zero side effectsSustained Energy Molecular hydrogen positively impacts mitochondrial function and supports both acute and chronic fatigue [19] Hydrogen’s ability to easily cross biological membranes, such as the double membrane surrounding mitochondria, allows easy entrance and quick action for those experiencing the increase in reactive oxygen and nitrogen species often associated with fatigue from disease states, stress, or high-intensity exercise [20]. In both animal and human studies, hydrogen has been shown to improve energy thanks to its antioxidant, anti-inflammatory, and even gene-level effects. It works within the mitochondria to quell hydroxyl radicals and block specific inflammatory pathways, such as the NLRP3 inflammasome. Weight Loss & Improved Body Composition Multiple studies have shown that supplemental hydrogen leads not only to weight loss but also improved body composition (fat-to-muscle ratio) [21,22]. In a study of middle-aged, overweight women, four weeks of hydrogen supplementation led to decreases in body fat percentage, serum triglycerides, and fasting serum insulin, likely due to hydrogen’s influence on obesity-associated mitochondrial dysfunction and inflammation. The participants also experienced an increase in the endogenous antioxidant CoQ10 along with an improved lactate-to-pyruvate ratio, indicating positive mitochondrial outcomes [23]. Immune Balance Investigations into the effects of hydrogen on autoimmune disease show a delay in the progression of experimental autoimmune encephalomyelitis, an experimental form of multiple sclerosis. Disease severity, central nervous system infiltration, and demyelination were reduced when hydrogen was administered after the onset of the disease [24]. Supplemental hydrogen’s antioxidant and anti-inflammatory actions, specifically its ability to scavenge hydroxyl radicals, make it a promising therapy for those with rheumatoid arthritis (RA). After 4 weeks of drinking hydrogen-enriched water, patients with RA had lower levels of oxidative marker 8-OHdG and decreased disease activity. Those with early RA achieved disease remission (25,26). Cognitive Performance A small study of hydrogen supplementation’s effect on cognitive function in older women found that those who received hydrogen scored significantly better on tests of mental function, including improvements in word recall and word recognition. The authors report that the average cognitive enhancement was significant enough for the group to progress from mild dementia at baseline to normal cognition at follow-up [27]. A second joint study examined memory-impaired animals and humans with mild cognitive decline. In mice, hydrogen water reduced oxidative stress, suppressed memory impairment and neurodegeneration, and even extended lifespan. After one year of hydrogen water, human participants with the APOE4 genotype, a known risk factor for Alzheimer’s disease, scored significantly better on the Alzheimer’s Disease Assessment Scale, while the control group received slightly worse scores [28]. The Healing Power Of Hydrogen In Every Glass Metabolic Protection A randomized, double-blinded, placebo-controlled study of 30 men and 30 women with metabolic syndrome found that 24 weeks of hydrogen water consumption led to: 18.5 mg/dL reduction in total cholesterol 47 mg/dL reduction in triglycerides 18.4 mg/dL reduction in fasting glucose 12% reduction in HbA1c Reduction of inflammatory markers TNF-a, IL-6, and CRP Additionally, the antioxidant vitamins E and C significantly increased in the group drinking hydrogen water. These effects are likely due to hydrogen’s antioxidant capabilities but may also be related to its positive influence on the electron transport chain, the series of biochemical steps leading to ATP production [29]. Skin Health Hydrogen-rich water may be both internally and externally beneficial for the skin! One small Japanese study found that direct application of hydrogen water to the skin significantly decreased wrinkles, skin blotchiness, and modulated oiliness, meaning it reduced oiliness in participants with excessively oily skin and increased it in participants with dry skin. The authors speculate that the potent antioxidant action of hydrogen water was responsible for mitigating reactive oxygen species damage that leads to skin aging [30]. Hydrogen also shows promise for those healing from skin damage due to radiation. In a recent animal study, radiation-induced skin wounds healed more quickly in the group sprayed with hydrogen water, likely due to lowered levels of malondialdehyde, a marker of oxidative stress, and IL-6, an inflammatory marker. Further, the wounds treated with hydrogen water had increased superoxide dismutase activity, an endogenous antioxidant enzyme [31]. Exercise Performance & Recovery The influence of supplemental hydrogen on athletic performance reveals that even short-term supplementation may have positive benefits on endurance, fatigue, respiratory rate, heart rate, blood lactate levels, and perceived effort [32, 33, 34]. Additionally, hydrogen encourages recovery from soft tissue injuries [35]. Hydrogen’s unique role as a supporter of endogenous antioxidant production makes it particularly valuable to active people who want to achieve optimal health and improved performance. Research shows it balances exercise-induced oxidative stress and may even act as an alkalinizing agent capable of combating fatigue during high-intensity exercise [36]. How Did We Create Drinkable Hydrogen? The answer is a simple (and very safe) chemical reaction—the form of magnesium used in Molecular Hydrogen reacts with water to produce hydrogen gas. For maximum benefit, begin drinking immediately after your tablet dissolves. It won’t be a struggle—Molecular Hydrogen is flavored with 100% natural raspberry powder. Molecular Hydrogen: Supporting Metabolism For Over 2 Billion Years (You read that right.) According to the Hydrogen Hypothesis, hydrogen is the link between evolution and the development of our primary energy producers—mitochondria [37]. Billions of years ago, we evolved with a need for hydrogen. That requirement was fulfilled by the microscopic ancestors of present-day mitochondria. How does evolution affect you today? Research shows that molecular hydrogen has a profound positive impact on metabolism and mitochondrial health. Supplemental Hydrogen Supports Mitochondrial Functions, Including: Balanced cholesterol [38] Metabolic stability [39, 40] Optimal body composition Liver capacity [41,42] Cardiovascular fitness [43] Healthy blood pressure [44] References National Center for Chronic Disease Prevention and Health Promotion, Division for Heart Disease and Stroke Prevention. Heart Disease Facts. Last Reviewed: May 15, 2023. Division of Cancer Prevention and Control, Centers for Disease Control and Prevention. An Update on Cancer Deaths in the United States. Page last reviewed: February 28, 2022. Hirode G, Wong RJ. Trends in the Prevalence of Metabolic Syndrome in the United States, 2011-2016. JAMA. 2020;323(24):2526-2528. Mizuno K, Sasaki AT, Ebisu K, et al. Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life. Med Gas Res. 2018;7(4):247-255. Barancik M, Kura B, LeBaron TW, Bolli R, Buday J, Slezak J. Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems. Antioxidants (Basel). 2020;9(12):1281. LeBaron TW, Singh RB, Fatima G, et al. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes. 2020;13:889-896. Kato S, Saitoh Y, Iwai K, Miwa N. Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes. J Photochem Photobiol B. 2012;106:24-33. LeBaron TW, Singh RB, Fatima G, Kartikey K, Sharma JP, Ostojic SM, Gvozdjakova A, Kura B, Noda M, Mojto V, Niaz MA, Slezak J. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes. 2020;13:889-896. Qiu P, Liu Y, Zhang J. Recent Advances in Studies of Molecular Hydrogen against Sepsis. Int J Biol Sci. 2019;15(6):1261-1275. Tarnava A. Supersaturated Hydrogen-Rich Water Hydrotherapy for Recovery of Acute Injury to the Proximal Phalanges on the 5th Toe: A Case Report. JoSaM. 2021;3(1). Fu Z, Zhang J, Zhang Y. Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases. Oxid Med Cell Longev. 2022;2022:2249749. Yamamoto H, Ichikawa Y, Hirano SI, Sato B, Takefuji Y, Satoh F. Molecular Hydrogen as a Novel Protective Agent against Pre-Symptomatic Diseases. Int J Mol Sci. 2021;22(13):7211. Pizzino G, Irrera N, Cucinotta M, et al. Oxidative Stress: Harms and Benefits for Human Health. Oxid Med Cell Longev. 2017;2017:8416763. Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr. 2010;46(2):140-149. Trivic T, Vojnovic M, Drid P, Ostojic S. Drinking hydrogen-rich water for 4 weeks positively affects serum antioxidant enzymes in healthy men: a pilot study. Current Topics in Nutraceutical Research. 2017;15(1). Sim M, Kim CS, Shon WJ, Lee YK, Choi EY, Shin DM. Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial. Sci Rep. 2020;10(1):12130. Tian Y, Zhang Y, Wang Y, et al. Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis. Front Physiol. 2021;12:789507. Mohd Noor MNZ, Alauddin AS, Wong YH, et al. A Systematic Review of Molecular Hydrogen Therapy in Cancer Management. Asian Pac J Cancer Prev. 2023;24(1):37-47. Hirano SI, Ichikawa Y, Sato B, Takefuji Y, Satoh F. Molecular Hydrogen as a Medical Gas for the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Possible Efficacy Based on a Literature Review. Front Neurol. 2022;13:841310. Zhou K, Liu M, Wang Y, et al. Effects of molecular hydrogen supplementation on fatigue and aerobic capacity in healthy adults: A systematic review and meta-analysis. Front Nutr. 2023;10:1094767. Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. Obesity (Silver Spring). 2011;19(7):1396-1403. LeBaron TW, Singh RB, Fatima G, et al. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes. 2020;13:889-896. Korovljev D, Trivic T, Drid P, Ostojic SM. Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women. Ir J Med Sci. 2018;187(1):85-89. Zhao M, Liu MD, Pu YY, et al. Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice. J Neuroimmunol. 2016;294:6-13. Ishibashi T. Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases. Curr Pharm Des. 2013;19(35):6375-6381. Ishibashi T, Sato B, Rikitake M, et al. Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Med Gas Res. 2012;2(1):27. Korovljev D, Trivic T, Drid P, Stater V. Short-Term H2 Inhalation Improves Cognitive Function in Older Women: A Pilot Study. International Journal of Gerontology. 2020;14(2):149-150. Nishimaki K, Asada T, Ohsawa I, et al. Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. Curr Alzheimer Res. 2018;15(5):482-492. LeBaron TW, Singh RB, Fatima G, et al. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes. 2020;13:889-896. Tanaka Y, Miwa N. Repetitive Bathing and Skin Poultice with Hydrogen-Rich Water Improve Wrinkles and Blotches Together with Modulation of Skin Oiliness and Moisture. Hydrogen. 2022; 3(2):161-178. Zhou P, Lin B, Wang P, Pan T, Wang S, Chen W, et al. The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats, Journal of Radiation Research. 2019;60(1):17–22. Mikami T, Tano K, Lee H, et al. Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study. Can J Physiol Pharmacol. 2019;97(9):857-862. LeBaron TW, Larson AJ, Ohta S, et al. Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study. J Lifestyle Med. 2019;9(1):36-43. Botek M, Krejci J, Mckune A, Sládečková B, Naumovski N. Hydrogen Rich Water Improved Ventilatory, Perceptual and Lactate Responses to Exercise. Int J Sports Med 2019;40(14):879-885. Ostojic SM, Vukomanovic B, Calleja-Gonzalez J, Hoffman JR. Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. Postgrad Med. 2014;126(5):187-195. Ostojic SM. Molecular hydrogen in sports medicine: new therapeutic perspectives. Int J Sports Med. 2015;36(4):273-279. Martin W, Müller M. The hydrogen hypothesis for the first eukaryote. Nature. 1998;392(6671):37-41. Todorovic N, Fernández-Landa J, Santibañez A, Kura B, Stajer V, Korovljev D, Ostojic SM. The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis. Pharmaceuticals. 2023; 16(2):142. Kajiyama S, Hasegawa G, Asano M, et al. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008;28(3):137-143. Asada R, Tazawa K, Sato S, Miwa N. Effects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers. Med Gas Res. 2020;10(3):114-121. Korovljev D, Stajer V, Ostojic J, LeBaron TW, Ostojic SM. Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial. Clin Res Hepatol Gastroenterol. 2019;43(6):688-693. Kura B, Szantova M, LeBaron TW, Mojto V, Barancik M, Szeiffova Bacova B, Kalocayova B, Sykora M, Okruhlicova L, Tribulova N, et al. Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial. Antioxidants. 2022; 11(10):1935. Saengsin K, Sittiwangkul R, Chattipakorn SC, Chattipakorn N. Hydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future application. Cell Mol Life Sci. 2023;80(6):174. Sugai K, Tamura T, Sano M, et al. Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension. Sci Rep. 2020;10(1):20173.

Introducing the LR Superfood Starter by Cutting Edge Cultures—the ultimate solution for crafting a unique cultured dairy product at home. Key Features Unique Cultured DairyUnlike conventional yogurt, LR Superfood is a distinct cultured dairy product fermented with Lactobacillus reuteri bacteria, offering a pleasantly tangy flavour and smooth texture. 'Low and Slow' FermentationFermented at a consistent 100°F (approximately 37.8°C) for 36 hours, this method allows the beneficial bacteria to proliferate extensively, resulting in a rich and creamy cultured dairy product. High-Quality IngredientsContains live cultures of Lactobacillus reuteri (LR007 strain) and non-GMO fructooligosaccharides (FOS). Note: Packaged in a facility that also handles products that may contain wheat, soy, eggs, milk, and fish. Product Details Form: Powdered starter culture Quantity: Each package contains 4 sachets, sufficient to make up to twenty 1-litre batches. Storage: Store in the refrigerator or freezer upon receipt to maintain potency. This product is formulated to be shipped without refrigeration. Suggested Uses Homemade Cultured DairyCreate your own batch of LR Superfood at home, enjoying its unique taste and texture. Culinary IngredientIncorporate into smoothies, dressings, or desserts for added flavour and creaminess. Summary Instructions for Use (See images above or link below for full instructions) Prepare the MixtureIn a clean glass jar, combine 2 tablespoons of prebiotic fibre (such as Prebio Plus) with the contents of 1 sachet of LR Superfood Starter. Add approximately 1.5 cups of dairy (cold, or up to 100°F/37.8°C). Whisk well to avoid clumping and ensure even distribution. Do not blend. Add Remaining DairyStir in the remainder of the dairy, leaving some headspace in the jar. Mix well for even distribution. Do not blend. FermentationCover the jar lightly with a loosely fitting lid or plastic wrap. Ferment at 100°F (37.8°C) for 36 hours, away from direct airflow and other ferments. Do not stir or open the jar during fermentation. StorageOnce fermentation is complete, refrigerate the cultured dairy to slow down bacterial activity and preserve freshness. ReculturingUse a portion of your finished LR Superfood to culture subsequent batches, repeating the process several times as desired. Find Full Instructions at https://cuttingedgecultures.com/lr-dairy-instructions/ Find FAQs at https://cuttingedgecultures.com/lr-faqs/ Please note:  This product is packaged in a facility that also handles products that may contain wheat, soy, eggs, milk, and fish. Elevate your home fermentation projects with the LR Superfood Starter by Cutting Edge Cultures—bringing the art of cultured dairy making to your kitchen with ease and precision.

WHAT'S IN ENERGENESIS?   Energenesis is like a 5-star MEAL for your Mitochondria (LOADED with rare nutrients, energy boosters and powerful antioxidants, because your body needs a variety – each one works differently!) AND… we have gone to amazing lengths to source the highest quality ingredients, with unparalleled potency, purity, biological availability, and effectiveness…   If you want to see a breakdown of the exact ingredients and amounts, you can look in the right column of the image below…   It’s a potent cocktail of the most powerful mitochondrial regenerating ingredients designed to literally CHARGE your cells back up, so you can have the energy you had when you were young – ALL DAY ENERGY.   If you’ve been struggling with fatigue or low energy levels, it’s time to stop dragging yourself through the day with caffeine and stimulants…   It’s time to start building REAL ENERGY.   You can certainly use the information here to go out and buy all these compounds as separate supplements, but I strongly encourage you to simply get Energenesis. It’s obviously far more convenient to get everything in one formula rather than fiddling with 20 different bottles and 25 pills each day. Also, you don’t have to worry about dosing everything correctly.   And, on top of that, I’ve tried to make it a complete no brainer for you by making it way cheaper for you to order it this way (as opposed to buying 20+ different supplements).   Energenesis is simply the most powerful formula ever developed for that purpose.UNLIKE PREVIOUS GENERATION “ENERGY SUPPLEMENTS,” IT CONTAINS NO STIMULANTS, NO CAFFEINE, AND NO SUGAR. THIS ISN’T ABOUT GIVING YOU A FAKE ENERGY BOOST, WHILE ACTUALLY MAKING YOUR ENERGY LEVELS WORSE OVER TIME. Energenesis builds REAL ENERGY! This is not a supplement designed to fill to people’s desire for quick fixes and instant gratification through stimulants and temporary boosts of fake energy. Energenesis is for people looking for REAL ANSWERS, who want to address ROOT CAUSES, and want to build real energy at the cellular level. As a result, the energy your mitochondria produce naturally decreases over time, reducing your health and longevity — and ultimately, causing fatigue. On top of that, stressors in our life — from psychological stress, to environmental toxins (like heavy metals and air pollutants), to a poor diet, to poor gut health, to chronic inflammation — all cause mitochondrial damage, dysfunction and shut down (they shift out of energy mode into a cell protection response). Research is now showing that these three things — the loss of mitochondria, the damage/dysfunction of mitochondria, and the shut down of mitochondria — are the primary factors that drive low energy levels. In other words, if you’ve got low energy levels, it likely simply means that your mitochondria have become weak, damaged, dysfunctional, and switched off over time.   ENERGENESIS INGREDIENTSWhat's Inside The Most Powerful Energy Supplement Ever CreatedMITOCHONDRIAL MEMBRANE SUPPORT COMPLEX   NT FACTOR PHOSPHOLIPIDS   NTFactor® is a digestion-resistant phospholipid complex that supplies the materials necessary to repair and regenerate damaged cell membranes directly to mitochondria, a treatment called lipid replacement therapy [1].    By supplying the bioactive phospholipids that mitochondria require to naturally replace damaged membrane components, NTFactor® is able to regenerate dysfunctional mitochondria, increase energy production, and enhance the energy levels of those using it.   Numerous studies have shown that NTFactor® reduces fatigue by 24–43 percent among those with chronic fatigue syndrome or conditions associated with fatigue, like general aging, obesity, lyme disease, and Gulf War Illness [2]. In older adults, NTFactor® restored mitochondrial function to a level matching healthy 29 year-olds [3].   ASTAXANTHIN   Astaxanthin is one of the most powerful membrane-specific antioxidants in existence. Not only is it 30–85 percent more potent than vitamin E and carotenoids like β-carotene, lycopene, and lutein [4], but it has a unique polar structure that allows it to cross through, protect, and stabilize the entire mitochondrial membrane [5].   Due to astaxanthin’s consistent and powerful ability to prevent oxidative damage and dysfunction to mitochondria [6–8], some researchers have even determined it to be “mitochondria-targeted antioxidant” [9].   Interventions have shown that astaxanthin supplementation increases muscular strength and power output in fatigued adults [10], enhances muscular endurance and recovery in recreational athletes [11,12], and reduces muscle damage and oxidative stress in elite soccer players [13].   MITOCHONDRIAL ENERGY PRODUCTION COFACTOR COMPLEX   ACETYL-L-CARNITINE   Acetyl-L-Carnitine (ALCAR) is a special form of carnitine that achieves two goals: (1) it supplies the carnitine your mitochondria need to produce energy, and (2) it provides an acetyl moiety that your mitochondria use to remain youthful and healthy.   The carnitine shuttle system is essential for bringing fatty acids into mitochondria to be used for energy production, and carnitine deficits (even mild ones) have been documented in those with chronic fatigue [14]. Moreover, over 20 percent of mitochondrial proteins rely on acetyl moieties to properly function, including those involved in antioxidant defenses and energy production [15,16].   For these reasons, some researchers have proposed that ALCAR should be considered a “mitochondrial rejuvenator” [17]. In chronically fatigued older adults, ALCAR supplementation led to profound benefits to their wellbeing — a 24 percent increase in physical function and close to a whopping 50 percent reduction in mental fatigue, physical fatigue, and overall fatigue severity [18].   CREATINE   Creatine is a molecule necessary for rapid and explosive energy production when energy needs cannot be immediately met by our mitochondria. Supplementation works by increasing the amount of available creatine within our muscles.   This not only increases muscular performance, but also helps stimulate mitochondrial energy production when faced with signals to do so (like being physically active) [24], enhance mitochondrial biogenesis and integrity [25], and protect mitochondria from oxidative damage [26,27].   Accordingly, creatine is one of the most extensively researched supplements for improving exercise performance, muscle strength, and power output in people of all ages [28–32].   COENZYME Q10   Coenzyme Q10 (CoQ10) is an essential component of mitochondrial energy production, serving as both an antioxidant and an energy-transferring molecule. As such, deficits in CoQ10 will not only lead to a cessation of energy production, but also an increase in oxidative damage.   Individuals with chronic fatigue regularly show deficiencies in CoQ10 concentrations throughout the body [33], as do those with conditions in which fatigue is a common symptom, like fibromyalgia [34–36], those who have survived heart attacks or heart failure [37,38], and multiple sclerosis [39,40].   Supplementation with CoQ10 improves fatigue, autonomic nervous system activity (the part of the nervous system involved in rest and recovery), and biochemical parameters of mitochondrial energy production in those with chronic fatigue [41–44], and reduces general fatigue and oxidative stress in healthy adults [45,46].   ALPHA-LIPOIC ACID (IDEALLY R-ALA)   Alpha-lipoic acid (ALA) is a mitochondrial molecule involved in energy metabolism and the antioxidant system. It is not only essential for mitochondria to create cellular energy, but also serves to function as an antioxidant, replenish other antioxidants, and stimulate the production of antioxidant enzymes like glutathione [47].   Accordingly, ALA has been heavily investigated as a mitochondrial rejunivator, able to help reverse age-related declines in mitochondrial energy production [48], particularly within the brian [49,50].    By improving mitochondrial function and protecting against oxidative stress, ALA has been shown to benefit metabolic health [51,52], as well as facilitate weight loss among those who are overweight [53–55].   ALA exists as either an S or R isomer, with unspecified ALA being a 50-50 ‘racemic’ solution of both. Most studies use the racemic solution, but only R-ALA has biological activity in the body and is more bioavailable [56], which is why we use it in Energenesis.   NAD+ REGENERATION COMPLEX   TAURINE   Taurine is an omnipresent amino acid within the body, essential for the development and function of our cardiovascular, muscular, nervous, and ocular systems [57]. It’s also essential for mitochondrial energy production and protein synthesis [58,59]   The highest amounts of taurine are in tissues with huge energy requirements and a lot of mitochondria, such as the retina, nerves, kidney, heart, and skeletal muscle [60]. If mitochondria don’t have enough taurine, energy production decreases and oxidative stress increases [61].   Insufficient taurine has been implicated in numerous chronic disease states [62,63], and several clinical trials have shown that supplementing with taurine reduces oxidative stress and inflammation in those with metabolic dysfunction [64–66].   Additionally, a meta-analysis reported that taurine supplementation improved endurance exercise performance, particularly power output and the amount of time that people could run before exhaustion [67].   MAGNESIUM   Magnesium is required for over 300 enzymes to function properly — muscle contractions, blood vessel regulation, insulin signaling, the synthesis of DNA and proteins, and nerve transmission all require magnesium [68].   One of the enzymes that relies on magnesium is ATP synthase, which is responsible for generating cellular energy (ATP) within mitochondria. Without magnesium, your mitochondria simply can’t function efficiently [69,70].   Energenesis provides two forms of magnesium, citrate and malate, which are both cofactors for mitochondrial energy production themselves.   B3 VARIANTS (NMN, NR, NIACIN & NIACINAMIDE)   Niacin is an essential component of energy-carrying molecules within the mitochondria, all of which are derivatives of nicotinamide adenine dinucleotide (NAD+). NAD+ is important for energy production, mitochondrial function, and cellular repair processes.   The primary route of NAD+ synthesis is through something called the salvage pathway, in which niacinamide serves as the starting molecule. We can also make NAD+ from nicotinic acid using an alternative pathway, which is why we’ve included both forms in Energenesis to ensure that NAD+ generation is not being impeded by a simple vitamin insufficiency.   MITOCHONDRIAL ENERGY PRODUCTION COFACTOR COMPLEX   POMEGRANATE   Pomegranate is a rich source of ellagitannins, potent antioxidant molecules that can be further metabolized into other antioxidant derivatives like ellagic acid and urolithins [71,72]. These substances have been heavily investigated for their mitochondrial and cardiovascular benefits.   Pomegranate ellagitannins and their derivatives have been shown to enhance mitochondrial function [73] and increase rates of mitophagy (mitochondria + autophagy) [74,75], which is a quality control pathway that preserves mitochondrial health by targeting damaged mitochondria for autophagic degradation, making anything that facilitates mitophagy absolutely vital for optimal health and disease prevention.   In recreational endurance athletes, supplementing with pomegranate extract for just two weeks increased the total time the athletes could cycle before complete exhaustion by 14 percent and increased the amount of time they could rely on their mitochondria to supply most of their energy by 10 percent [76].   Moreover, pomegranate supplementation has been shown to reduce blood lipid oxidation and the accumulation of plaque in arteries [77], particularly in people who have higher levels of oxidative stress [78,79].   GREEN TEA CATECHINS   Green tea (Camellia Sinensis) catechins are four phytochemical molecules, the most potent one being epigallocatechin-3-gallate (EGCG). It has been implicated in benefiting almost every organ system in the body in doses you can obtain easily from simply drinking green tea [87–89].   EGCG is neuroprotective [90,91], cardioprotective [92,93], anti-obesity [94–96], anti-carcinogenic [97,98], and anti-diabetic [99], all due primarily to its ability to stimulate mitochondrial biogenesis, enhance energy production, and protect mitochondria from oxidative stress [100,101].   Supplementation of EGCG plus resveratrol (another ingredient of Energenesis) has been shown to significantly increase mitochondrial function and the use of fatty acids for energy production [102], and several meta-analyses have concluded that EGCG reduces body weight and body fat [103–106], particularly abdominal fat [107].    GYNOSTEMMA   Gynostemma is a climbing vine native to SouthEast Asia and related to Panax Ginseng, containing many of the same bioactive molecules. Unlike ginseng, however, gynostemma also possesses an array of gypenosides that have been shown to upregulate several signaling molecule likes sirtuins and AMPK which facilitate mitochondrial function and biogenesis [108–110].   Clinical trials have shown that supplementation with gynostemma improves metabolic health through these mechanisms. A study of overweight men and women reported that supplementing with 450 mg of gynostemma daily for 12 weeks reduced total abdominal fat by 6%, visceral fat by 10%, and subcutaneous fat by 4% compared to a placebo [111].   Drinking 6 grams of gynostemma in the form of a tea lowered fasting glucose and insulin resistance each by 30% compared to a placebo after 12 weeks in adults with type 2 diabetes [112], and supplementing with 80 mL of gynostemma extract may improve liver health alongside dieting more than dieting alone in adults with fatty liver disease [113].   ASHWAGANDHA (SHODEN EXTRACT)   Ashwagandha (Withania somnifera) is a nightshade revered in Ayurvedic medicine for its physical- and mental-enhancing effects [114]. Today, it’s considered an adaptogen for similar reasons, able to increase a person’s resilience to stress and help reduce anxiety [115,116].   These effects are largely due to its constituent withanolide structures, which have several important neuroprotective effects within the brain, such as scavenging free radicals, reducing neuroinflammation, and promoting neurotransmitter signaling [117]. They also improve mitochondrial function and energy production [118].   In Energenesis, we use the most potent form of ashwagandha, a 35% withanolide concentrate called the Shoden extract. Just 240 mg of Shoden ashwagandha reduces stress and anxiety by 30% in mildly stressed adults [119], while a mere 60 mg can boost DHEA-S and testosterone by 15–18% in middle-aged men [120].   In another large randomized placebo-controlled trial of 150 men and women, supplementing 120 mg has been documented to improve physical and psychological quality of life by 8% and enhance sleep quality by 40% compared to placebo, including dramatically improving the time it took to fall asleep, total sleep time, and nightly awakenings [121].   Other studies have shown ashwagandha supplementation to reduce perceived stress, anxiety, and depression in mildly stressed healthy adults [122,123], adults battling chronic mental stress [124], and adults with an anxiety disorder [125].   PANAX GINSENG   Panax ginseng has been used medicinally for thousands of years in China, Korea, and Japan to alleviate physical and mental fatigue. While there are several types of ginseng on the market, panax ginseng is considered the “true” ginseng.   At a fundamental level, panax ginseng works to protect mitochondria from oxidative damage and improve energy production under conditions of oxidative stress [126,127]. A systematic review and meta-analysis of five studies in chronic fatigue patients found significant benefits of ginseng supplementation for reducing fatigue severity [128], with reductions of 20 percent after one month not being uncommon [129,130].   PQQ (PYRROLOQUINOLINE QUINONE)   Pyrroloquinoline Quinone (PQQ) is a potent stimulator of pathways involved in mitochondrial biogenesis and antioxidant defenses [131,132]. In particular, it stimulates pathways shared by exercise training and is believed to potentiate and enhance activity-induced benefits on mitochondria [133].   Supplementation has been shown to reduce fatigue and increase vigor by 20 percent in adults complaining of poor sleep and energy levels, as well as improve mood, sleep quality, and overall quality of life [134]. In another study of healthy adults, PQQ reduced inflammation and improved markers of mitochondrial respiration [135].   References

WHAT YOU CAN EXPECT FROM ULTRABRAIN Improved mood (combat depressed mood and increase joy) Improved focus and cognitive performance Improved brain energy levels Decreased brain fog (improved clarity) Decreased anxiety Stimulant-free brain boosting action Long-term decreased risk of neurodegenerative diseases DO YOU HAVE ANY (OR ALL) OF THESE SYMPTOMS?Brain-Related fatigue - Feeling fatigued, exhausted, or sleepy after doing something mentally demanding Chronic low-energy - waking up feeling groggy, feeling tired throughout the day, relying on caffeine or stimulants to keep you alert Brain fog - a type of cognitive dysfunction that includes memory problems, lack of ability to concentrate, and lack of mental clarity Anxiety or depression - persistent feelings of sadness, emptiness, guilt, hopelessness, worry, or pessimism Sleep problems - racing thoughts at bedtime or inability to fall asleep quickly, waking up in the night - sometimes repeatedly, insomnia Loss of resiliency - inability to handle and recover from stress Whether you suffer from one or all of these issues, you must understand this critical truth: These symptoms are NOT a normal thing, and they're NOT just a normal part of aging! HERE'S THE REALITY These symptoms are present because you actually have damaged, inflamed, or dysfunctional neurons in your brain more specifically, you have:   Leaky blood-brain barrier – a shockingly common issue where the protective wall between your brain and bloodstream breaks down when it becomes leaky, things get into the brain that shouldn’t be there.   Mitochondrial dysfunction/shutdown –  mitochondria are your cellular energy generators and danger sensors, but, mitochondria cannot be in both energy mode and cell defense mode.  When your mitochondria are weak, they are constantly trying to sense danger and can’t produce energy.   Neuroinflammation – cells in your brain called microglia, which sort of function as your brain’s immune system, are activated too frequently and become stuck in the on position, as a result, they produce inflammatory compounds and oxidative damage.   LET'S FIX THE DAMAGED NEURONS IN YOUR BRAIN! You CAN seal your blood-brain barrier, heal your mitochondria, and reduce the inflammation in your brain! You CAN reverse your brain-related fatigue, brain fog, anxiety and depression, loss of resilience, and sleep issues! To do this you must:   Nourish your imbalanced brain with a wide range of nutrients – nutrients that are scientifically proven to fix your neurons Reverse cellular dysfunction Reduce inflammation Rewire your brain out of fatigue, stress, and depression mode   WHY THESE SPECIFIC NUTRIENTS? The result is a very carefully curated formulation that meets these unparalleled standards:   Absolutely zero pseudo-sciences, facts, or false marketing. Pure science in every serving Each ingredient is in its most potent, bioavailable form. Really nothing else can outperform these brain-boosting compounds. Effective dosages in each and every serving. 6 capsules a day is everything you need to help reverse cellular dysfunction and supercharge your mental capacity   THE PERFECT FORMULATION 15 Premium, carefully sourced ingredients in effective dosages.   RHODIOLA ROSEA   Stabilizes mood Reduces anxiety and depression Improves cognitive performance Reduces feelings of exhaustion, irritability, and burnout Increases resilience (resistance to stress) Functions as an antioxidant and anti-inflammatory Fast-acting Rhodiola is a neuroprotective, cognitive enhancing, and mood stabilizing herb that promotes neuronal regeneration, functions as an antioxidant and anti-inflammatory, facilitates neurotransmission, and regulates several key mediators of the stress response [1–3].   The effects are rapid. In adults with chronic work- and life-related stress, rhodiola significantly reduced feelings of exhaustion, irritability, and anxiety in as little as three days [4].   In a study of working adults suffering from burnout, a third of whom had been unsuccessfully treated for their stress in the past, rhodiola improved every aspect of quality of life and perceived stress after just 1 week, with further improvements seen after 12 weeks [5].   In adults with chronic fatigue syndrome, rhodiola improved every aspect of fatigue after just 1 week, with further improvements seen after 8 weeks [6]. Ultimately, 83% of the participants reported “very much” or “much” improved conditions, with every aspect of fatigue, stress, and global impairment being cut in half.   Improvements in perceived stress, mental fatigue, cognitive performance, anxiety, and depression have also been noted in medical students [7], military cadets [8], and adults with stress-related fatigue [9], mild anxiety [10], and mild-to-moderate depression [11,12].   LION'S MANE POWDER   Reduces anxiety and depression Helps improve memory, concentration, and overall cognitive function Promotes nerve growth and regeneration in the brain Reduces inflammation Stabilizes mood Restores key neurotransmitters Lion’s mane mushroom (Yamabushitake or Hericium erinaceus) is a medicinal mushroom that has been extensively studied for its neurohealth properties [13,14].   Stimulates the production of nerve growth factor [15–17], which promotes neuronal growth, development, and regeneration [18]. Stimulates the production of brain derived neurotrophic factor [19], which has neuroprotective effects, plays a role in neuronal development, and helps in the formation of neuronal connections important for memory and cognition [20]. Restores levels of serotonin, noradrenaline, and dopamine levels in the brain that can be suppressed due to chronic stress [19]. Reduces neuroinflammation [19,21] Clinical trials have shown that lion’s manse improves cognitive function by 12% compared to placebo in older adults with mild cognitive impairment [22], and reduces symptoms of anxiety (by 27%) and depression (by 39%) in adults with obesity [23].   ALPHA-GPC   Protects neurons in the brain and supports neurotransmission Increases dopamine and serotonin signaling in the brain Decreases risk of vascular dementia More effective than Alzheimer drug (Aricept) at improving cognition Alpha-glycerophosphocholine (Alpha-GPC) is a highly bioavailable source of choline for the brain [24], which plays a critical role in neuronal plasticity, membrane stability, signaling events, and neurotransmission [25].     Having adequate brain choline concentrations is neuroprotective against a variety of brain diseases [26], and numerous clinical trials have found that alpha-GPC improves cognitive function and memory in individuals with neurodegenerative disorders, vascular dementia, and stroke — even being more effective than the standard drug therapy for Alzheimer’s disease [27].   CHOLINE (COGNIZIN®)   Promotes the health of cell membranes Improves memory and overall brain cognition Improves motor function Increases focus and reduces impulsive behavior Improves neuroplasticity (helps the brain adapt to new situations) CDP-choline is a bioavailable source of choline for the brain and the direct precursor for the synthesis of phosphatidylcholine [28,29], one of the most abundant and important structural components of cell membranes. Supplementation has been confirmed in humans to increase phosphatidylcholine synthesis within the brain [30,31].   A Cochrane Systematic Review of 14 double-blind, placebo-controlled trials involving older adults with cognitive deficits like dementia reported that CDP-choline was able to improve memory, correct abnormal behaviors, and increase the global impression that physicians have towards the participants [32].   Other studies have found that CDP-choline slows the deterioration of cognition in those with Alzheimer’s disease [33,34], improves motor function and attention in adolescents [35], and improves attention in healthy women [36].   BACOPA   Enhances short-term and long-term memory Enhances learning, visual processing, cognitive performance Improves mood and reduces depression and anxiety Reduces oxidative stress Neuroprotective Reduces β-amyloid deposits Enhances communication between neurons Increases blood flow Bacopa monnieri is an Ayurvedic swamp plant (Brahmi) traditionally used for the enhancement of memory and cognition, as well as a general brain tonic. Its bioactive constituents, the bacosides, have numerous biological effects within the brain that facilitate this use [37–41]:   Reduces oxidative stress and increases antioxidant enzyme activity Reduces inflammation Neuroprotective Reduces β-amyloid deposition Increases the growth of nerve endings to enhance neuronal communication Increase blood flow and the delivery of oxygen and nutrients Numerous clinical trials have found that bacopa supplementation improves working memory, attention, learning rate, information processing, and a variety of other cognitive outcomes in healthy elderly adults [42–44], healthy middle-aged adults [45,46], young medical students [47], and adults with Alzheimer’s disease [48].   GINKGO BILOBA   Neuroprotective Improves memory and cognitive performance Works as an antioxidant Counteracts cognitive impairment Improves neuroplasticity Preserves brain receptors in aging adults Ginkgo biloba possesses neuroprotective and antioxidant effects that preserve brain receptors susceptible to age-related loss, counteract cognitive impairment, enhance neuronal plasticity, and improve memory [49].     A systematic review of 12 meta-analyses found that ginkgo biloba improves cognitive performance, activities of daily living, and clinical global impression in the treatment of dementia [50], provided that at least 240 mg was used daily for several months [51].   COFFEE FRUIT (COGNATIQ™)   Increases Brain-Derived Neurotrophic Factor (BDNF) Powerful antioxidant Improves neuroplasticity Helps to  grow new neurons and prevent neurodegeneration Improves long-term memory CognatiQ™ is a patented extract of the whole coffee fruit, including both the coffee bean and the fruiting body surrounding it, which contains many powerful antioxidant compounds [52,53].   Clinical studies in healthy adults have shown that CognatiQ™ nearly doubles concentrations of brain-derived neurotrophic factor (BDNF) after 1–2 hours [54,55], beating out other forms of coffee bioactives, caffeine, and the phytochemical-rich grape seed extract.     BDNF is a key protein involved in brain health, well established to be critical for:   Neuroplasticity (helps the brain adapt to new situations) [56]. Neurogenesis (the growth, regeneration and creation of new neurons and synapses) [57,58]. Long-term memory [59]. Prevention of neurodegeneration [60]. HUPERZINE A   Promotes learning Used for centuries to treat brain-based illnesses Improves cognition, especially in people with Alzheimer’s and vascular dementia Naturally occurring acetylcholinesterase inhibitor (primary class of drugs for treating Alzheimer’s and dementia) Huperzine-A is a naturally occurring acetylcholinesterase inhibitor, which functions to inhibit the enzyme that degrades acetylcholine, the neurotransmitter responsible for learning new information [61].   A meta-analysis of 20 randomized controlled trials found that huperzine A supplementation improves cognitive function, daily living activity, and global clinical assessments over 8–36 weeks [62]. Other meta-analyses have reported that huperzine A improves cognition in those with vascular dementia [63], as well as in those with major depression [64].   ACETYL-L CARNITINE   Improves brain function, especially memory and attention Reduces oxidative stress Protects against β-amyloid neurotoxicity Reduces mental and physical fatigue Reduces depression – more effective than antidepressant drugs! (And with far fewer side effects) Reduces pain and increases nerve conduction Prevents progression of brain-related disease Acetyl-L-Carnitine (ALCAR) is a special form of carnitine that achieves two goals: (1) it supplies the carnitine your mitochondria need to produce energy, and (2) it provides an acetyl moiety that your mitochondria use to remain youthful and healthy.   ALCAR easily crosses the blood-brain barrier and preserves mitochondrial function within the brain that otherwise deteriorates with aging [65–69]. Notably, ALCAR concentrations slowly decline as cognitive impairment progresses, ultimately being 36% lower in Alzheimer’s patients than healthy adults [70].     A meta-analysis of 21 randomized controlled trials involving patients with mild cognitive impairment or Alzheimer’s disease found that ALCAR significantly improved cognitive function and prevented the progression of Alzheimer’s after as little as 3 months [71].   In elderly adults suffering from excessive fatigue, ALCAR improved cognitive function by 15%, reduced mental and physical fatigue by 43–52%, and improved the ability to function in daily life by 24% [72].   A meta-analysis of 12 randomized controlled trials found 3 g/d of ALCAR to significantly reduce depressive symptoms with an efficacy similar to antidepressant drugs, but with far less side effects [73].   SAFFRON EXTRACT   As effective as prescription drugs (with less side effects) in:   Reducing depression Treating obsessive compulsive disorder (OCD) Improving cognitive function Antioxidant and anti-inflammatory Neuroprotective Saffron is one of the most well-researched antidepressant compounds available, with three separate meta-analyses of randomized controlled trials indicating that 30 mg/d has a potency comparable to prescription drugs but with less side effects [74–76].   Other studies have shown that saffron is as effective as prescription drugs for treating obsessive compulsive disorder (OCD) [77], and boosts cognitive function to the same extent as prescription drugs in those with Alzheimer’s disease [78,79].   L-THEANINE   L-theanine is a naturally occurring amino acid found in tea that alters neurotransmitter signaling within the brain. After consumption, it crosses the blood-brain barrier, interferes with excitatory glutamate signaling, stimulates dopamine release, and promotes inhibitory neurotransmission, thereby helping promote a state of relaxation [80,81].   Electroencephalography (EEG) studies have shown that theanine shifts brain waves towards alpha oscillatory patterns indicative of a relaxed state, particularly in those with high levels of baseline anxiety [82–86]. Accordingly, several studies have found that theanine supplementation improves feelings of relaxation, tension, calmness, and anxiety in the hours following [87,88].   AGMATINE SULFATE   Important neurotransmitter Improves learning and memory Reduces anxiety and depression Protects neurons and enhances cell growth Protects mitochondria More effective at relieving pain than conventional medications Agmatine is a neurotransmitter and neuromodulator (affects neurotransmission of entire neurons) that has anti-seizure, anti-pain, anti-anxiety, and antidepressant effects; modulates some of the processes involved in learning and memory; and interacts with the mechanisms of drug withdrawal [89].   Preliminary research has shown that agmatine supplementation causes a “total/incontrovertible remission of depression” without apparent adverse effects in those who were not responsive to conventional treatments [90].   In a randomized, double-blind, placebo-controlled study of individuals with back pain from herniated lumbar discs, agmatine reduced pain by 25–28% and improved parameters of general health by 65–76% after just two weeks [91].     POLYGALA TENUIFOLIA   Improves memory and combats forgetfulness Supports neurotransmitters required for learning, memory, and mental health Promotes growth of new neurons in the brain Increases neuroplasticity and cognitive function Polygala tenuifolia is one of the fundamental herbs used in traditional Chinese medicine, used to improve memory and combat forgetfulness with aging [92], which it does by:   Inhibiting the breakdown of acetylcholine, dopamine, serotonin, and noradrenaline, neurotransmitters required for learning new information, memory storage, and overall mental health [93,94]. Increasing the expression of brain derived neurotrophic factor (BDNF), which is fundamental for neuroplasticity and neurogenesis [95]. Promoting the growth of new neurons in the brain [96]. In a clinical trial of healthy adults, Polygala tenuifolia improved spatial, verbal, and working memories [97]. In a separate randomized, double-blind, placebo-controlled study of elderly adults, Polygala tenuifolia improved cognitive function by 5–10% [98].   N-ACETYL-L-TYROSINE   Critical for stress management Boosts cognition, alertness, and information processing Improves memory and mental health L-tyrosine is a conditionally essential amino acid that serves as the precursor molecule from which we create the catecholamines: dopamine, adrenaline, and noradrenaline. Your brain needs a steady supply of tyrosine to make the catecholamines and keep your mental health at its peak [99,100], particularly if you are under a lot of stress [101].   Several clinical trials have shown that L-tyrosine supplementation boosts cognition, alertness, and memory in stressful and demanding situations in otherwise healthy adults [102,103], such as those who skimp on their sleep [104], undergo intense physical training [105], or those who endure extreme temperatures [106].   MAGNESIUM TAURATE   Over 300 enzymes require magnesium to function properly! Required for optimal nerve transmission Protects against cell death Prevents mitochondrial dysfunction Prevents migraines Improves anxiety and depression Slows development of and severity of Parkinson’s and Alzheimer’s Reduces risk of stroke Magnesium is required for over 300 enzymes to function properly [107]. Within the brain and nervous system, magnesium is required for optimal nerve transmission and protection against excitotoxicity (excessive excitation leading to cell death) [108,109].   A systematic review of magnesium’s role in neurological disorders found that it plays an important role in the prevention of migraines, treatment of anxiety and depression, severity of Parkinson’s disease, development of Alzheimer’s disease, and protection against stroke [110].   But, not all forms of magnesium are the same. Magnesium taurate demonstrates a superior ability to enter into the brain and increase the brain’s magnesium status compared to other forms [111,112].   References

Rapidly Boost Cellular Glutathione Glutathione is the most important molecule you need to maintain your health. Continual-G with Glyteine® kick starts your body’s glutathione production. It’s the most effective way to boost cellular glutathione, the body’s master antioxidant. Nothing else delivers glutathione into your cells faster!Continual-G with Glyteine® and Sunfiber® now offers extended benefits The Glyteine® in Continual-G signals your body to make additional glutathione. It’s the only ingredient in supplement form that has been clinically proven to raise cellular glutathione levels above homeostasis with a single dose. Glyteine® is the proprietary form of the dipeptide Gamma-Glutamylcysteine (GGC), the immediate precursor to the tripeptide glutathione. Glutathione is the body’s master antioxidant. It is used by our body to defend against free radicals and combat oxidative stress. Aging reduces the homeostatic levels of cellular glutathione levels and which get elevated with the Glyteine® present in Continual-G. Continual-G provides your cells with the concentration of glutathione necessary to protect them against exposure to common toxins. Intense physical activity rapidly decreases cellular glutathione levels and which can be quickly brought back to normal with Continual-G. Recycling key antioxidants such as vitamin C & E consumes glutathione which is replenished with Continual-G. Research has shown that glutathione is necessary to increases the effectiveness of Vitamin D. Continual-G rapidly provides the essential glutathione. Continual-G is the ONLY supplement available with Glyteine® inside. We have developed Continual-G now into a super supplement and have replaced maltodextrin with Sunfiber® — a partially hydrolyzed guar gum or PHGG. PHGG is a water-soluble dietary fiber. You will now be able to enjoy all the benefits of Continual-G and Sunfiber® in a single convenient powder beverage. Benefits of Sunfiber® Natural, gluten-free and low FODMAP** Gentle and supports your gut health Helps you feel less hungry Helps decrease post-meal glucose spikes by reducing the glycemic index of your food How To Use Take CONTINUAL-G twice daily, once in the morning and once at night. Cellular glutathione levels reach their peak within two hours. Continual-G is easy to add to your wellness routine: ADD TO WATER Simply mix one lemon-lime flavored sachet into 6-8 ounces of water, preferably at room temperature. Stir well. Or, add one pack to a partially filled water bottle. Shake vigorously until completely dissolved. BLEND INTO A SMOOTHIE OR OTHER BEVERAGE Mix with a beverage of your choice till completely dissolved. Continual-G Helps Your Body Stay Stronger For LongerFor Boosting Daily Immunity Neutralizes excess free radicals in your cells and supports your immune function. For Sports Recovery Supports optimal physical activity and ensures faster muscle recovery after intensive exercise. For Healthy Aging Supports brain, liver, and other organ functions by neutralizing excess free radicals.

What Is BenaGene Oxaloacetate? BenaGene Oxaloacetate is a four-carbon molecule, a critical component in the production of adenosine triphosphate (ATP). ATP is the main energy source for the majority of all cellular functions. It must be constantly regenerated, because without adequate ATP, our cells cannot function properly. See image in images. This product consists of two compounds, which already exist in human bodies, oxaloacetic acid and Vitamin C. Thus, it is not a drug. It is rather a nutritional supplement, which optimises clear cognitive potential and supports brain health. BENEFITS OF OXALOACETATE Since it is found in every cell of our bodies, Oxaloacetate as an energy molecule is critical to human metabolism. Clinical trials have documented significant glucose level reductions in diabetic patients who used this product. Although benaGene does lower high glucose levels, it does not cause hypoglycaemia in non-diabetic patients. Main benefits of the product are: higher energy levels in your body sleep improvement decreased sugar cravings decreased ability to create and store fat in your body increased sense of relaxation and general well-being BenaGene Oxaloacetate maintains healthy neurons in the brain, as well as the nervous system. It does so by insuring that there is no toxic build-up of glutamate in your body. It has also been shown to increase the protective effects of zinc on human eye cells. By supporting the DNA and other already mentioned tissues, this product may reduce the risk of many age-related degenerative conditions. It is also a strong anti-oxidant. ANTI-AGING BENAGENETM100MG OF ACTIVE BENAGENETM brand Thermally Stabilized Oxaloacetate for optimizing the body's response to the aging process. benaGeneTM contains the nutrient oxaloacetate which in Laboratory studies has been proven to increase lifespan in mammals by mimicking the life extending effects of caloric restriction. 100% natural and without side effects, benaGeneTM can offer you an edge against time. *  [1 month supply]    DISCUSSION: benaGeneTM contains oxaloacetic acid, a key intermediate in the Kreb's Cycle. Studies demonstrate that benaGeneTM mimics a caloric restriction diet, which has been shown to increase the expression of beneficial genes associated with increased life span, health span, weight management and blood glucose reduction. *   30 Gel-Caps ________________________________________________________ SUPPLEMENT FACTS:Serving Size: 1 Capsule                                                             %DV _________________________________________________________________ benaGeneTM (Oxaloacetate, Oxaloacetic Acid) .......... 100 mg              **Vitamin C (Ascorbic Acid)........................................ 100 mg           167% _________________________________________________________________ Based on a 2,000 Calorie per day Diet.**Dietary Reference Intake not established. Non-medicinal ingredients: Rice Flour, Magnesium Stearate. Capsule; Gelatin, Titanium dioxide (white) and blue #7.Suggested UseTake one capsule daily with food or as directed by a qualified health practitioner. Do not use during pregnancy and lactation.Main applicationsAs reported by literature:   Anti-Aging. *   Glucose metabolism. *SourcePharmaceutical synthesis. Pregnancy / NursingDo not use during pregnancy and lactation.CautionsDo not use during pregnancy and lactation. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is It Memory Loss?   Or sleep loss? Lack of sleep can lead to... Impaired memory [1] Decreased cognitive ability [2] Poor mood [3] Imbalanced immune function Increased risk of infectious disease [4] Vascular inflammation Increased risk of cardiovascular disease [5] Higher risk of sarcopenia - involuntary loss of muscle mass [6] Emotional dysregulation [7] Low libido [8] Cravings & weight gain [9] Metabolic syndrome [10] Hormonal imbalances [11] Decreased fertility & ability to conceive [12]     "In addition to elevated risks of chronic diseases, short sleep duration is strongly associated with decreases in cognitive performance... ...impairments in several cognitive domains can be observed even after short-term sleep restriction" [13]. Nature Journal, October 2021       Add 4 Pills To Your Night...And Extra Years To Your Life. Sleep deprivation has deadly consequences, especially for women. You might feel tired today, but over time, your health takes an enormous hit. The most impactful illnesses and disasters of the 21st century are linked to lack of sleep. Incredibly, a follow-up investigation of the space shuttle Challenger disaster named staff sleep loss as a possible cause [14]. The risk of obesity, metabolic syndrome, hypertension, heart attack, stroke, Alzheimer’s disease, and cancer, particularly the increasingly prevalent colorectal cancer, increase with suboptimal sleep [15, 16]. And women are affected more than men. Females with disturbed sleep have greater chances of cardiovascular disease, increased insulin, hypertension, and inflammation compared to males [17]. Mental health also suffers—symptoms of depression, anxiety, psychosis, and stress perception worsen with sleep loss. Those with insomnia, for instance, have a two-fold risk of developing depression compared to those without the condition [18, 19].     Imagine 8 Restful Hours Instead Of 5 Restless Ones. A Calm Mind Instead Of Racing Thoughts. The best part? No Rx hangover. Human Optimization Lab's Sleep may support: Non-habit forming REM sleep without the side effects of Rx drugs [20] Healthier balance of non-REM and REM sleep patterns [21] Sounder sleep versus waking up tired before your alarm clock [22, 23] Increased sleep time [22] Faster transition from awake to asleep—no more tossing & turning [22] Alleviation of insomnia, specifically related to age [22, 24, 25] Less chance of waking during the night [26] Reduced symptoms of restless legs syndrome [27] Antioxidant balance and anti-inflammatory effects [28] Reduced anxiety [29] Healthier circadian rhythms, even in the presence of unavoidable light at night [30] Production of your body's own master antioxidant, melatonin [31] Fewer obsessive thoughts that keep you awake [32]     Sleep's dream team: Melatonin & your mitochondria When you think of antioxidants, what comes to mind? Most of us imagine berries, dark chocolate, or vitamins C and E. But the real antioxidant all-star? Melatonin. Melatonin is an incredibly potent and unique antioxidant. Why? Unlike other antioxidants, it's created by your mitochondria and plays enormous roles in optimizing their function...and your energy levels [33].     Ingredients Based On Science, Not Social Media. Sleep is formulated with nutrients and doses proved effective in scientific studies…and only those nutrients. We don’t believe in proprietary blends or hidden excipients. Learn more about our transparent, evidence-based ingredients.     Magnesium (Magnesium Glycinate) Magnesium aids sleep in multiple ways, yet aging is a risk factor for magnesium deficiency. Magnesium relieves muscle tension [35] and is an N-Methyl-D-aspartic acid (NMDA) antagonist and GABA agonist, meaning it gently reduces neuronal excitability and promotes neuronal relaxation.     Potassium (Potassium Glycinate) Sleep is divided into two phases, non-rapid eye movement (NREM) and rapid eye movement (REM) and five separate stages! This organization is called sleep architecture, and potassium is best known for supporting these patterns thanks to its role in regulating the intricate physiology of potassium channels in the nervous system [36].     B6 (Pyridoxal 5’-Phosphate) Pyridoxal 5′-phosphate (PLP), the biologically active form of vitamin B6, is a cofactor for kynurenine aminotransferase (KAT) and kynureninase (KYNU), two key enzymes in the conversion of kynurenine to tryptophan [38]. In turn, we use tryptophan to make both serotonin and melatonin [39].     Herbatonin® (Plant Melatonin) Does melatonin leave you feeling drowsy throughout the morning? Interestingly, a double-blind, placebo-controlled study from MIT found 0.3 mg of melatonin to be the ideal dose for people with insomnia over 50 [24]. When compared to the pharmacological dose of 3 mg, the 0.3 physiological dose restored sleep efficiency without remaining elevated into the daytime.     L-Theanine L-theanine is a non-protein amino acid abundant in green tea, well known for its relaxing effects and ability to cross the blood-brain barrier [40]. Once in the brain, l-theanine blocks glutamate receptors and enhances GABA and dopamine, resulting in reduced neuro-excitability and increased feelings of relaxation [41].     L-Tryptophan L-tryptophan is an essential amino acid that plays an integral part in nervous system health and is the precursor to serotonin, a key hormone for mood regulation (43). Clinical studies of tryptophan-deficient diets show that low intake of this essential amino acid results in increased depression, anxiety, and poor emotional processing [44].     L-Serine L-serine is a non-essential amino acid studied for its remarkable neuroprotective effects [47]. Researchers have hypothesized that dietary L-serine may be responsible for the large centenarian population in Ōgimi, Okinawa, due to their exceptionally high intake of L-serine through foods such as seaweed, tofu, and pork. [48]. The average Ōgimi woman eats over 8 grams of dietary L-serine daily, while her American counterpart only gets 2.5 grams [49].     5-HTP 5-HTP is an amino acid produced from tryptophan and is a metabolic intermediate to serotonin and melatonin. 5-HTP has been studied for its anti-depressant, anxiolytic, and sleep-promoting effects. Several neurodegenerative diseases have been associated with low levels of 5-HTP, including Parkinson’s, fibromyalgia, and Alzheimer's [54].     Myo-Inositol Myo-inositol is a fascinating but commonly underconsumed compound primarily found in organ meats. It was once considered a B vitamin, but its classification changed when endogenous creation from glucose was discovered in the kidneys, liver, and brain.     Chamomile Extract (Matricaria Recutita) For hundreds of years, chamomile has been one of the most trusted, aromatic sleep herbs. It's properties include anti-anxiety, stress relieving, and anti-insomnia. It's also beneficial to the immune and digestive systems and the liver [60]. What people say about Sleep     I have struggled with sleep most of my life, and for the last 10 years have tried many different supplements after finally stopping all sleep medications. Some of these supplements have helped, but I have been using Sleep and find that it combines all the different supplements I have tried into one! It works beautifully, it not only helps me ease into sleep quickly, but when I wake in the middle of the night, I can fall back to sleep. I wake up feeling relaxed but not groggy. I am loving this supplement!!   References Peng Z, Dai C, Ba Y, Zhang L, Shao Y, Tian J. Effect of Sleep Deprivation on the Working Memory-Related N2-P3 Components of the Event-Related Potential Waveform. Front Neurosci. 2020;14:469. Alhola P, Polo-Kantola P. Sleep deprivation: Impact on cognitive performance. Neuropsychiatr Dis Treat. 2007;3(5):553-567. Triantafillou S, Saeb S, Lattie EG, Mohr DC, Kording KP. Relationship Between Sleep Quality and Mood: Ecological Momentary Assessment Study. JMIR Ment Health. 2019;6(3):e12613. Garbarino S, Lanteri P, Bragazzi NL, Magnavita N, Scoditti E. Role of sleep deprivation in immune-related disease risk and outcomes. Commun Biol. 2021;4(1):1304. Hijmans JG, Levy M, Garcia V, et al. Insufficient sleep is associated with a pro-atherogenic circulating microRNA signature. Exp Physiol. 2019;104(6):975-982. Li X, He J, Sun Q. Sleep Duration and Sarcopenia: An Updated Systematic Review and Meta-Analysis. J Am Med Dir Assoc. 2023;24(8):1193-1206.e5. Saghir Z, Syeda JN, Muhammad AS, Balla Abdalla TH. The Amygdala, Sleep Debt, Sleep Deprivation, and the Emotion of Anger: A Possible Connection?. Cureus. 2018;10(7):e2912. Kalmbach DA, Arnedt JT, Pillai V, Ciesla JA. The impact of sleep on female sexual response and behavior: a pilot study. J Sex Med. 2015;12(5):1221-1232. Greer SM, Goldstein AN, Walker MP. The impact of sleep deprivation on food desire in the human brain. Nat Commun. 2013;4:2259. Chasens ER, Imes CC, Kariuki JK, et al. Sleep and Metabolic Syndrome. Nurs Clin North Am. 2021;56(2):203-217. Beroukhim G, Esencan E, Seifer DB. Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review. Reprod Biol Endocrinol. 2022;20(1):16. Kloss JD, Perlis ML, Zamzow JA, Culnan EJ, Gracia CR. Sleep, sleep disturbance, and fertility in women. Sleep Med Rev. 2015;22:78-87. Csipo T, Lipecz A, Owens C, et al. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021;11(1):20994. Mitler MM, Dement WC, Dinges DF. Sleep medicine, public policy and public health. In Kryger MH, Roth T, Dement WC (eds). Principles and Practice of Sleep Medicine, 3rd Edition, Philadelphia: WB Saunders, 2000;580-588. Medic G, Wille M, Hemels ME. Short- and long-term health consequences of sleep disruption. Nat Sci Sleep. 2017;9:151-161. Sabia S, Fayosse A, Dumurgier J, van Hees VT, Paquet C, Sommerlad A, et al. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun. 2021 Apr 20;12(1):2289. Suarez EC. Self-reported symptoms of sleep disturbance and inflammation, coagulation, insulin resistance and psychosocial distress: evidence for gender disparity. Brain Behav Immun. 2008;22(6):960-968. Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Med Rev. 2021;60:101556. Baglioni C, Battagliese G, Feige B, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011;135(1-3):10-19. Poceta JS. Zolpidem ingestion, automatisms, and sleep driving: a clinical and legal case series. J Clin Sleep Med. 2011;7(6):632-638. Benington JH, Woudenberg MC, Heller HC. Apamin, a selective SK potassium channel blocker, suppresses REM sleep without a compensatory rebound. Brain Res. 1995;692(1-2):86-92. Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169. Sutanto CN, Loh WW, Kim JE. The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression. Nutr Rev. 2022;80(2):306-316. Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia. J Clin Endocrinol Metab. 2001;86(10):4727-4730. Zick SM, Wright BD, Sen A, Arnedt JT. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study. BMC Complement Altern Med. 2011;11:78. Drennan MD, Kripke DF, Klemfuss HA, Moore JD. Potassium affects actigraph-identified sleep. Sleep. 1991;14(4):357-360. Jadidi A, Rezaei Ashtiani A, Khanmohamadi Hezaveh A, Aghaepour SM. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial. BMC Complement Med Ther. 2022;23(1):1. Kukula-Koch W, Szwajgier D, Gaweł-Bęben K, Strzępek-Gomółka M, Głowniak K, Meissner HO. Is Phytomelatonin Complex Better Than Synthetic Melatonin? The Assessment of the Antiradical and Anti-Inflammatory Properties. Molecules. 2021;26(19):6087. Rao TP, Ozeki M, Juneja LR. In Search of a Safe Natural Sleep Aid. J Am Coll Nutr. 2015;34(5):436-447. Ohashi M, Lee SI, Eto T, et al. Intake of L-serine before bedtime prevents the delay of the circadian phase in real life. J Physiol Anthropol. 2022;41(1):31. Maffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020;22(1):181. Harvey BH, Brink CB, Seedat S, Stein DJ. Defining the neuromolecular action of myo-inositol: application to obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2002;26(1):21-32. Tan DX, Manchester LC, Qin L, Reiter RJ. Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics. Int J Mol Sci. 2016;17(12):2124. Reiter RJ, Ma Q, Sharma R. Melatonin in Mitochondria: Mitigating Clear and Present Dangers. Physiology (Bethesda). 2020;35(2):86-95. Altura BM, Altura BT. Tension headaches and muscle tension: is there a role for magnesium?. Med Hypotheses. 2001;57(6):705-713. Patel AK, Reddy V, Shumway KR, et al. Physiology, Sleep Stages. [Updated 2022 Sep 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan. Heizhati M, Zhang Y, Shao L, et al. Decreased serum potassium may disturb sleep homeostasis in essential hypertensives. Hypertens Res. 2019;42(2):174-181. Deac OM, Mills JL, Shane B, et al. Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults. J Nutr. 2015;145(4):701-707. Richard DM, Dawes MA, Mathias CW, Acheson A, Hill-Kapturczak N, Dougherty DM. L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. Int J Tryptophan Res. 2009;2:45-60. Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007;74(1):39-45. Williams JL, Everett JM, D’Cunha NM, et al. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review. Plant Foods Hum Nutr. 2020;75(1):12-23. Hidese S, Ogawa S, Ota M, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019;11(10):2362. Kikuchi AM, Tanabe A, Iwahori Y. A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning. J Diet Suppl. 2021;18(3):316-333. Jenkins TA, Nguyen JC, Polglaze KE, Bertrand PP. Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis. Nutrients. 2016;8(1):56. Hudson C, Hudson SP, Hecht T, MacKenzie J. Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia. Nutr Neurosci. 2005;8(2):121-127. Sutanto CN, Loh WW, Kim JE. The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression. Nutr Rev. 2022;80(2):306-316. Ye L, Sun Y, Jiang Z, Wang G. L-Serine, an Endogenous Amino Acid, Is a Potential Neuroprotective Agent for Neurological Disease and Injury. Front Mol Neurosci. 2021;14:726665. Cox PA, Metcalf JS. Traditional Food Items in Ogimi, Okinawa: l-Serine Content and the Potential for Neuroprotection. Curr Nutr Rep. 2017;6(1):24-31. Yasuo S, Iwamoto A, Lee SI, et al. l-Serine Enhances Light-Induced Circadian Phase Resetting in Mice and Humans. J Nutr. 2017;147(12):2347-2355. Bolsius YG, Zurbriggen MD, Kim JK, et al. The role of clock genes in sleep, stress and memory. Biochem Pharmacol. 2021;191:114493. Yasuo S, Iwamoto A, Lee SI, et al. l-Serine Enhances Light-Induced Circadian Phase Resetting in Mice and Humans. J Nutr. 2017;147(12):2347-2355. Ohashi M, Lee SI, Eto T, et al. Intake of L-serine before bedtime prevents the delay of the circadian phase in real life. J Physiol Anthropol. 2022;41(1):31. Maffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020;22(1):181. Meloni M, Figorilli M, Carta M, et al. Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease. Sleep Breath. 2022;26(3):1023-1031. Sutanto C, Heng CW, Gan AX, Wang X, Fam J, Kim JE. The Impact of 5-Hydroxytryptophan Supplementation on Sleep Quality of Older Adults in Singapore: A Randomized Controlled Trial. Curr Dev Nutr. 2021;5(Suppl 2):372. DiNicolantonio JJ, H O’Keefe J. Myo-inositol for insulin resistance, metabolic syndrome, polycystic ovary syndrome and gestational diabetes. Open Heart. 2022;9(1):e001989. Wei H, Landgraf D, Wang G, McCarthy MJ. Inositol polyphosphates contribute to cellular circadian rhythms: Implications for understanding lithium’s molecular mechanism. Cell Signal. 2018;44:82-91. Bojarskaite L, Bjørnstad DM, Pettersen KH, et al. Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep. 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All-Natural Liquid TRACE MINERAL Element #49 Original Patented 99.9% Pure INDIUM . . . the Missing-Link 1 mg. Pure INDIUM Per Drop, 60-90 Days Supply After 25 years of research & development by Schroeder and Bonadio and thousands of personal reports from satisfied users, for the first time in history 99.9% pure Liquid Indium advanced-food is available at the advent of the 21st century. ~~ INDIUMEASE ~ THE Silver Bullet ~~~ You can live without INDIUM, but you may not achieve Optimum Longevity without it ~ The 7th-rarest Mineral # 49 on the Periodic Table, INDIUM, until now was not bioavailable, therefore all plants & animals are 99% deficient. INDIUM is the "Missing Link" unifying two major Mineral groups, for the first time in history INDIUM is made bioavailable by the patented process #6,007,847 for an evolutionary feeling of easy living. What does rare INDIUM do, besides raising average Mineral uptake 60 to 694% ? INDIUM (In) is a soft silvery supermetal discovered in 1850 .05 ppm. in earth ores, insoluble in water so only traces are taken up in the food chain and present in fauna or anima on autopsy. Indium was first tested in 200 mice compared to 200 controls by Dartmouth Medical School's Dr. Henry A. Schroeder, J.J. Balassa, Marian Mitchner, M. Kanisawa, A.P. Nason, and W.H. Vinton in 1964-68; who reported that INDIUM improved average Mineral absorption in the glands 142%; raised Chromium in all organs average 333%, enhancing Insulin that regulates muscle-building Protein and Carbohydrate energy in mammals. SAFETY:  Indium is among the safest of trace elements, safer than Selenium & most minerals;  there has never been a case of human poisoning from industrial use of Indium.  Indium-sulfate was granted F.D.A. “Generally Recognized As Safe” G.R.A.S. status.  Begin slowly, and Reduce Amount if under severe stress or multiple trauma to avoid too-speedy rejuvenation.  Take in moderation, not excess.  The recommended Patented INDIUM DAILY AMOUNT is 1 Drop per 50 lb. of body weight, containing 1 mg. 99.9% pure INDIUM as Indium-sulfate per drop.  Swallow Drops on back of tongue on an empty stomach upon arising (7-10 hours after last food);  & wait 10 minutes before eating.  Begin taking one drop per day the first week, raising by 1 drop per day each successive week, to normal amount. NOTE:  Indium has not been tested by any government agency, nor been approved to treat, cure, or prevent any disease.  The above science and testimony abstracts are true, accurate and complete to best knowledge at this time, spoken freely for education and research purpose only, but not intended as medical advice nor implied to give results for anyone anywhere similar to those summarized.  The best-known evidences to date result from objective scientific studies on animals, doctors’ reports, and citizens’ personal testimonies of proper IndiumEase usage of our advanced formula.  Be sure to consult a qualified physician for any health problem(s) you may have. INDIUMEASE  Tastes Terrifically Tart (like Blackberry or Pomegranate) & Works Wonderfully Well.   INDIUM Increases NUTRIENT MINERALS In VITAL ORGANS INDIUM Increases NUTRIENT MINERALS In VITAL ORGANS IN LIVER IN LUNGS IN HEART IN KIDNEYS IN SPLEEN INDIUM Increases Chromium Glandular Uptake Average 433%, or 333% more 1.66 = 332% 3.91 = 212% 24.32 = 636% 14.22 = 794% 7.65 = 190% .50 1.84 3.82 1.79 4.03 INDIUM Increases Copper Glandular Uptake Average 161%, or 61% more 25.3 = 128% 26.3 = 136% 47.6 = 146% 38.9 = 209% 44.8 = 188% 19.8 19.4 32.5 18.6 23.8 INDIUM Increases Manganese Glandular Uptake Average 194%, or 94% more 4.99 = 115% 5.16 = 190% 5.37 = 136% 8.29 = 225% 12.46 = 305% 4.34 2.71 3.95 3.68 4.08 INDIUM Increases Zinc Glandular Uptake Average 179%, or 79% more 202 = 138% 187 = 187% 152 = 146% 252 = 252% 268 = 172% 146 100 104 100 156   The implication is that the absorption and use of many mineral elements is, and always has been, poor; the "Limiting Factor" to optimal health, because there is no significant amount of soluble Indium in the biosphere. Indium is not "essential for life," or humans and animals would have died out; but Indium appears to be "essential for optimal health," or Level-2 of Nutrition, that wasn't available before Bonadio's Indium discovery. Of interest is that high Cadmium intake is often toxic, but Indium (In) being next heavier, may displace some of the toxicity of excess Cadmium. Indium is an inexpensive, preferred supplement for all types of animals, pets, and humans. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. REPORTS FROM INDIUM USERS The following are seven notarized statements prepared for the Comissioner of Patents: From a security policeman at a local hospital:   From sluggishness and no pep I changed into a feeling of happiness inside. People now tell me that I talk more friendly and smile easier. My sex drive has improved remarkably, for my 50 years of age, to like it was when I was 25. I have less anxiety, able to sit without being anxious to get up and move, with a clearness to my mind. From a financial trustee of a local synagogue:   I was down in the dumps at 76, but now feel radiant, more like living. I don't need as many hours of sleep, and I'm not as tired anymore when I get up; and more interested in daily affairs. Previously I did not want to get out of bed. From a doctor, possibly with cancer:   I have a little more energy ... less rawness in right chest ... improved energy and appetite ... totally free of irritations in the right chest for the first time in several months. Off of Indium for three days, now ... discomfort again in right chest. On Indium again, no rawness in chest. Vitality much improved. From an investment counselor:   I am sleeping about two hours less per night, and just as rested. I am more ambitious, with more drive, clearing up what I never touched before. I have such a sense of well-being that I could run back from lunch instead of walking. Mentally I am more organized, more clear. My mind is busy all the time. From a retired electrical contractor:   Indium has cleared my thinking up. Before I had to stop and sit down to collect my thoughts. Now I can think on the move. From a registered nurse, possibly with cancer:   The symptoms I had yesterday, in a haze and forgetful, with some numbness around mouth and tongue, have disappeared. I have more energy today, and feel better generally. I sleep very well, did not wake during the night as I usually do. I woke 1.5 hours before normal time, and felt relaxed. I lost three pounds of overweight, and still feel much better than two weeks ago (before Indium), and I'm doing more things. From a retired clergyman:   On Indium I find an improvement in rest so that I awaken a full hour before the alarm, and I am completely rested. A very definite libido improvement. (The above copyright by George A. H. Bonadio, 2000).     (The Testimonies below are from Indium users in 2003) (Female age-65) Last week I used the weed-wacker, and didn't need a nap afterwards ... I am sleeping better . . . not as   exhausted after mowing the lawn, and worked outside longer than usual after mowing. Indium works very gradually and gently. Amazing stuff !!  My daughter and I power-washed and stained both sides of my 6-foot cedar fence . . . using two sprayers   . . . and I didn't get tired. The prep work and clean-up was hard and grueling ... in 110 degree temps. In the past 7-8 years I have suffered mitral valve palpitations that would last from 2-4 hours . . . leaving me   feeling tired and weak for days. When I was younger the attacks would last only 5 minutes. Well, you can imagine how happy and surprised I was when this attack lasted only 10 minutes. Amazing, it had to be the Indium, as I can't attribute it to anything else. I was so grateful I started praising and thanking God out loud. I got up, had another drink of water, and went back outside to finish the front of the house, watered the flowers, and hosed down the front walk and driveway with no problems since !!! Today I vacuumed four rooms and cleaned the bathroom. I started getting a little tired, which slowly disappeared. Most nights I sleep well, very deep and restful. I have been feeling great ! Really wonderful and energetic. Couldn't really put my finger on it, but I would imagine this is what people feel like when they're on a "high" on drugs. Of course it's better for there's no "coming down." I cooked a big dinner Saturday, made some homemade coconut ice cream earlier in the week, baked a   birthday cake and had my daughter, her husband, and his 93-year-old grandmother over to celebrate her birthday. I had energy galore, and felt like  I did when I was fixing dinner in my 40's. Never tired all day. What a wonderful feeling !! I don't ever want   to be without Indium. My son-in-law has a sense of well-being and calmness on the Indium, in a much better mood, and more   relaxed at work. Red-faced, he told me how much the Indium has increased his sex drive, and that he wants his wife to start taking it so she can keep up with him. About 1-2 years ago I began noticing an ache in my lower back kick in every morning while brushing my   teeth. Just last week I noticed it was only present some mornings, and recently it disappeared completely after a month on Indium. This stuff is sure amazing. Hey, maybe some morning we'll wake up and find ourselves 25 again and all gorgeous and handsome !!! I did food shopping in the morning, mowed the lawn and hosed down the patio just in the nick of time   before thunder and rain came, showered, fixed dinner and never got tired until bedtime at 11 p.m. I was amazed. You were right when you said it delays the tiredness. I did what I needed to do when I needed to do it. (Female age-32) I have been able to get less sleep, and still have a decent energy level. Also my cycle has decreased from   42 days to 31 days. I have been operating on 4-6 hours of sleep a night, with tremendously busy days and little rest. Have gone   to bed after 1 a.m. the last three nights, and have to get up with my husband at 5 a.m. because the days have been so jam-packed, and very stressful. I need the extra oomph. Could you get another bottle of Indium to me? (Mother age-39 with a 12-year-old) My daughter, her friend and friend's mother, and I went camping to New Hampshire for the weekend. If it   wasn't for the Indium, I probably would not make it. The Indium is really great for energy and I am grateful to have it. (Female, early 40's, overweight, had ovarian cancer, on thyroid drugs for 15 years) Did I tell you how the Indium is working? I've been taking the Thyodine with it for the Iodine faithfully, and   cutting down on my thyroid meds. After 3 weeks, I'm only on the Indium and Thyodine now. Initially I was getting some shakes, so I did it slowly, and I was able to wean off my thyroid meds in 11 days and I feel terrific. No tiredness or anything. This stuff is fantastic. My husband also seems to have more energy. (Doctor, female, age-65) I think the Indium has really perked me up. Ever since my birthday party, when I got up at 5:20 to start   cleaning house preparing for it - and was up until 10:30 with friends, I seem to be forgetting my afternon naps. I can't imagine naturally having more energy just because I turned 65 !! I have tons of energy on Indium. Now I can keep up with my young husband ! Ha ha! (Female musician age-49) The Indium is giving me more energy. I had started to get a cold and seemed to shake it off faster. All in   all, I would say better on all fronts! Thanks! (Female librarian, age-45) I keep forgetting to use the Indium, only intermittent use for several months. I used to get an annoying eye   tick for as long as I can remember, which started when I least expected it, and would last for hours, sometimes days. I hated it. Ever since I've been taking the Indium, it hasn't happened. If Indium only did that for me. it's spectacular. I'll keep you informed. (Female, after using 1 bottle of Indium) I love IndiumEase. Please send me a 12-pack. (Female with a history of miscarriage) This lady was pregnant and bleeding heavily. After going on Indium for several weeks, the bleeding   stopped, and she is so happy expecting to go full term birthing a healthy baby. We'll keep you posted.    

A Formulation that Works* Based on the science of the Gut-Skin Axis, doctor- developed Gut to Glow™  is formulated with four powerhouse ingredients to help you feel and look more vibrant.* Lactobacillus reuteri LRDR™  Oxiceutics proprietary LRDR™ strain of Lactobacillus reuteri provides an important microbe that the great majority are missing in their gut. This microbe not only resides in the colon but also the upper GI tract. Daily incorporation of L. reuteri LRDR™  helps you support gut health and gut balance.* Marine Collagen The highly concentrated marine collagen hydrolysates in Gut to Glow™ are especially enriched in the dipeptides shown to firm skin by supporting collagen density and skin moisture and elasticity. It aims to support improved texture and plumper looking skin.* Hyaluronic Acid Oxiceutics Hyaluronic Acid taken orally supports skin hydration and the hyaluronic content in the dermal layer for smoother and more radiant skin. This supports the appearance of fine lines and wrinkles. Astaxanthin  With antioxidant properties, Astaxanthin is the most potent carotenoid known, with as much as 100-fold greater antioxidative effect compared to beta carotene. Suggested Use: 120 capsules (30-day supply), per bottle. Take 4 capsules a day. Note:  Oxiceutics do not recommend taking Gut to Glow if you are trying to get pregnant, are pregnant, or are nursing. Disclaimer: *These statements have not been evaluated by the Food and Drug Administration.  These products are designed to supplement a healthy diet and lifestyle, and are not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare professional before using any dietary supplement, particularly if you are pregnant, breastfeeding, have a medical condition, or are taking medication. Do not exceed the recommended daily dose. Keep out of the reach of children. If any adverse reactions occur, discontinue use and consult a healthcare provider.  FAQs by Oxiceutics Gut to Glow Why is Lactobacillus reuteri included in Gut to Glow? Oxiceutics' proprietary L. reuteri LRDR™  is included in Gut to Glow primarily to support gut balance.* Lactobacillus reuteri is a super microbe that has the ability to take up residence not only in the colon but also the upper GI tract. Can I combine Gut to Glow with my current collagen? You can combine or you can replace. Clinical studies show that much lower doses of marine sourced collagen hydrolysates are needed compared to other sources, as it is especially enriched in the bioactive peptides needed for skin and health benefits. How long will it take before I start to see improvements in my skin? An increase in moisture, and smoother skin within several weeks of starting is often reported. Reduced appearance of wrinkles typically becomes noticeable after 8 weeks. Of course, results can vary due to baseline skin condition and other factors. Remember, it's taken a while to get here, so patience on the journey is key. Typically, supplements take around 3 months to experience most benefits. Oxiceutics' expectation is that you will begin seeing gradual improvements sooner than that. For best results, stay consistent with taking 4 capsules/day. Are there interactions with other medications? We always recommend that you check with your health care professional prior to starting something new. However, as Gut to Glow provides nutrients that our bodies should be producing or obtaining from diet, the likelihood of an adverse reaction to any of the 4 ingredients is extremely rare. Why do probiotics often cause GI disturbances when you start taking them? I have noticed feeling a little gassy. Is this from Gut to Glow? Probiotics can cause GI disturbances as you are initially introducing good bacteria into your system, in an effort to support gut balance. While the "bad" bacteria is leaving, bloating, gas and other GI disturbances can be temporarily experienced. Lactobacillus reuteri is an important and powerful microbe that is, in a sense, “cleaning” your gut environment. It is totally normal to experience some gas and possible diarrhea at the beginning as it introduces changes into the intestinal microbiome. This is good news and will typically dissipate once your microbiome is used to the supplementation. If there is a probiotic microbe in Gut to Glow capsules, do they need to be refrigerated? There is no harm in refrigerating the supplements, but it is not necessary. They should, however, be stored in a cool, dry environment, out of the direct sun and with the jar kept closed to keep moisture away from the capsules. Can men take Gut to Glow? Absolutely! All the components of Gut to Glow are perfectly compatible with male physiology. Many of the same benefits that females experience can also be experienced by males. Why does the package say that Gut to Glow is best taken with a meal containing fats or oils? Fats and oils can assist with the absorption of the carotenoid component, astaxanthin. This could be olive oil in a salad, butter, a fatty meat or fish, or other oils or fats. If you include a fish oil supplement in your daily routine, taking it simultaneously with Gut to Glow is another option to assist with astaxanthin absorption. I read that hyaluronic acid taken orally is not digestible by humans. Is this true? Yes, it is true. Yet hyaluronic acid taken orally has been demonstrated to increase skin moisture and exert other healthy skin benefits. Although humans lack the digestive enzymes to break down hyaluronic acid, microbes in your colon break the hyaluronic acid molecules down into small fragments that are readily absorbed. We are therefore reliant on intestinal microbes for the absorption of hyaluronic acid. What is a nutricosmetic? A nutricosmetic marries the fields of nutrition and cosmetics. It is a nutritional supplement ingested to benefit skin, hair, or nails. Nutricosmetics support a beauty that starts from within. How do I take Gut to Glow? Oxiceutics recommend taking 2 capsules in the morning and 2 in the evening, with a fat containing meal. Some people prefer to take all 4 together. Consistency in taking 4 daily is most important, so please follow what works best with your daily regimen. What allergens are in Gut to Glow? Gut to Glow contains marine collagen sourced from fish. Gut to Glow is made without milk, egg, shellfish, tree nuts, wheat, peanuts, or soy. Is this safe to take while I am trying to get pregnant, pregnant or nursing? Oxiceutics recommend not taking Gut to Glow if you are trying to get pregnant, are pregnant, or are nursing. If I miss a dose, should I double up? If you forget to take one of your morning doses, it is fine to double up in the evening. There is no need to exceed 4 capsules a day, as Gut to Glow is formulated in scientifically backed amounts of each ingredient (in 4 capsules a day) for maximum benefit. I currently take a probiotic. Should I continue taking that? There is no reason to discontinue use as different microbes provide different benefits. As important as Lactobacillus reuteri LRDR™  is, it is important to take all steps in supporting gut balance. Why do I need to take 4 capsules/day? Oxiceutics optimised formulation is based on science. Studies have supported the amounts that Oxiceutics recommend in a daily dose for the most efficacious benefits. How long will one jar of Gut to Glow last? Each jar is a 30-day supply. There are 120 capsules in a jar and we recommend taking 4/day.

Unlock the secrets of vitality and longevity with our premium NMN capsules. NMN, a derivative of niacin (vitamin B3) that naturally occurs in the body, is a key player in the production of nicotinamide adenine dinucleotide (NAD+). Our NMN formula boasts unparalleled absorption efficacy and an impressive purity level of at least 99%, thanks to our cutting-edge enzymatic technology. A derivative of niacin (Vitamin B3) Exceptionally absorbable Supports cellular renewal & function 99% high purity Naturally boost NAD+ levels Anti-aging supplement Product DescriptionDiscover the pathway to vitality and longevity with our superior NMN capsules. Derived from niacin (vitamin B3), NMN is pivotal in generating nicotinamide adenine dinucleotide (NAD+), essential for cellular rejuvenation. Our NMN formula boasts unparalleled absorption efficacy and an impressive purity level of at least 99%, thanks to our cutting-edge enzymatic technology. With each capsule, you’ll harness the full potential of NMN to support cellular rejuvenation and overall vitality. IngredientsB-Nicotinamide Mononucleotide Shell Capsule: Hypromellose How to useAdults take 1 capsule on an empty stomach in the morning, preferably an hour before eating, with a glass of water (250ml). StorageStore in a cool, dry place away from direct sunlight. Refrigeration is not required. Nutrition InformationServing Size: 1 capsule (500mg) Servings in bottle: 60 Typical valuesPer serving (1 capsule) B-Nicotinamide Mononucleotide    500mg