The word “systemic” means body wide. Systemic enzymes are those that operate not just for digestion but throughout your body in every system and organ. But let’s take first things first, what is an enzyme?
First and foremost these body wide proteolytic (protein eating) enzymes have the following actions:
Anti-Fibrosis: Systemic Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that eventually kills us all.
Let me explain: As we age, which starts at 27, we have a diminishing of the bodies’ output of enzymes. This is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we are 27. At that point the body knows that if it keeps up that rate of consumption we’ll run out of enzymes and be dead by the time we reach our 40’s. (Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don’t make it past their 20’s before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue).
So, our body in it's wisdom begins to dole out our enzymes with an eyedropper instead of with a tablespoon; as a result, the repair mechanism of the body goes out of balance and has nothing to reduce the over abundance of fibrin it deposits in nearly every thing from simple cuts, to the inside of our internal organs and blood vessels. This is when most women begin to develop things like fibrocystic breast disease, uterine fibroids, endometriosis, and we all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin beginning to spider web its way inside of our internal organs reducing their size and function over time. This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars.
If we replace the lost enzymes we can control and reduce the amount of scar tissue and fibrosis our bodies have. As physicians in the US are now discovering, even old scar tissue can be “eaten away” from surgical wounds, pulmonary fibrosis, kidney fibrosis and even keloids years after their formation. Medical doctors in Europe and Asia have known this and have used orally administered enzymes for these situations for over 40 years!
Blood Cleansing: The blood is not only the river of life, it is also the river through which the cells and organs dispose of their garbage and dead material. Enzymes improve circulation by eating the excess fibrin that causes blood to sometimes get as thick as catsup or yogurt, creating the perfect environment for the formation of clots. All of this material is supposed to be cleared by the liver on its "first pass", or the first time it goes through but given the sluggish and near toxic or toxic states of everyone's liver these days that seldom happens. So the sludge remains in the blood waiting for the liver to have enough free working space and enough enzymes to clean the trash out of the blood. This can take days, and in some cases, weeks! (8).
When systemic enzymes are taken, they stand ready in the blood and take the strain off of the liver by:
- Cleaning excess fibrin from the blood and reducing the stickiness of blood cells. These two actions minimize the leading causes of stroke and heart attack causing blood clots. (8).
- Breaking dead material down small enough that it can immediately pass into the bowel. (8).
- Cleanse the FC receptors on the white blood cells improving their function and availability to fight off infection. (9). And here we come to the only warning we have to give concerning the use of systemic enzymes - don't use the product if you are a hemophiliac or are on prescription blood thinners like Coumadin and Heparin, without direct medical supervision. The enzymes cause the drugs to work better so there is the possibility of thinning the blood too much.
Immune System Modulating: Enzymes are adaptogenic seeking to restore a steady state to the body. (9). When the immune system is running low we become susceptible to infectious disease, when it’s cranked up too high then the system creates antibodies that attack it's own tissues as are seen in the auto immune diseases of MS, Rheumatoid Arthritis, and Lupus. Here the enzymes will tone down immune function and eat away at the antibodies the immune system is making to attack its bodies own tissue.
Virus and Bacteria Fighting: Viruses harm us by replicating in our bodies. To do this a virus must bond itself to the DNA in our cells through the medium of its exterior protein cell wall. Anything that disrupts that cell wall inhibits the ability of viral replication by rendering individual viruses inert. (10,11). Systemic enzymes can tell the difference between the proteins that are supposed to be in your body and those that are foreign or not supposed to be there, (again the enzyme lock and key mechanism). Serrapeptase has the strongest protein eating effect of any commercially available enzyme and can be of help in combating viruses.
Systemic Enzymes also have been found to have mild anti-bacterial properties. A bacteria is a foreign protein (exogenous). Proteolytic enzymes eat exogenous proteins in the body.
One note: many in the States have learned in school that enzymes are too big a protein to be absorbed through the gut. The pioneering research done in the US by Dr. Max Wolf (MD & PhD x7) at Columbia University in the 40’s through the 70’s has not made it to the awareness of most doctors. There are currently over 200 peer reviewed research articles dealing with the absorption, utilization and therapeutic action of orally administered systemic enzymes. A search through Pub Med using the key words: serrapeptase, papain, bromelain, trypsin, chymo trypsin, nattokinase and systemic enzyme will yield some of the extensive work. Systemic enzymes now have a 4 decade plus history of widespread medical use in central Europe and Japan.
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References:
1) Carroll A., R.: Clinical examination of an enzymatic anti-inflammatory agent in emergency surgery. Arztl. Praxis 24 (1972), 2307.
2) Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic
inflammation of otorhinolaryngology pathology: a multicentre, double blind,
randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast engorgement with Serrapeptase: a randomized double blind controlled trial. Singapore Med J. 1989:30(l):48-54.
4) Celebrex article Wall Street Journal 19 April 1999.
5) No author listed: Regular Use of Pain Relievers Can Have Dangerous Results. Kaleidoscope Interactive News, American Medical Association media briefing. July 24, 1997.
6) Enzymes ñ A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher MD. Published 1993 Eco Med.
7) Kakinumu A. et al.: Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.
8) Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994.
9) Kunze R., Ransberger K., et at: Humoral immunomodulatory capasity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160.
11) Bartsch W.: The treatment of herpes zoster using proteolytic enzymes. Der Informierte Arzt. 2 (1974), 424-429.
Why Zymessence®: Because You Asked and We Listened! The New Formula is Even Stronger!
You asked for a systemic enzyme that did not need to be taken by the handful (not the recommended dose on the label but how many you actually have to take to get good effects, usually: 10 - 60 capsules/tablets a day).
You asked for a systemic enzyme that was affordable.
What Makes Zymessence® Better: It's All in the Mix!
Zymessence™ is part of an emerging "new breed" of products in the field of Systemic Enzyme Therapy. It combines the best of both the "Old School" and the "New School" science of proteolytic enzymes to form a super effective and affordable blend.
The "Old School" Systemic Enzymes, blended animal pancreatin (usually a 4X, 6X, 8X or 10X dilution) with fruit enzymes and then added Trypsin and Chymotrypsin extracts (also from Pancreatin) to create a wide-ranging and effective action. The drawback is Trypsin and Chymotrypsin are extremely expensive so not a lot is put into each tablet or capsule! The upside to using animal based pancreatin is research and clinical experience show that these enzyme blends last 24 to 36 hours in the body.
The "New School" Systemic Enzymes, blend fruit, vegetable and fermented fungal based enzymes (such as fermented Serrapeptase), to increase the action of their product. As Serrapeptase is substantially stronger than Trypsin or Chymotrypsin, it does in fact increase the effectiveness of these enzyme blends several fold. The drawback is that clinical experience and research both show that these enzyme products only have 4 to 6 hours of action before they leave the body. The upside is Serrapeptase, though stronger, is far less expensive than Chymotrypsin and Trypsin so more can be put into each tablet or capsule!
Zymessence® takes a page from the "Old School":
Zymessence® takes a page from the "New School":
And More... Zymessence® uses "enteric matrix technology":
Dear Dr. Wong:
I am on my 2nd bottle of Zymessence and LOVE it. I have MS and Fibromyalgia therefore cannot live without Zymessence for imflammation and immune support! AND, as a bonus it has helped my allergic reactions that I've developed to peanuts and some grains-stopped skin from itching, etc.
Rita B.
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