Vimergy Vimergy Herbs - Celeryforce 60caps (Magnesium Glycinate, Inositol, L-Glutamine, L-Taurine, and Choline)
£21.00
Celeryforce® A special blend of Magnesium Glycinate, Inositol, L-Glutamine, L-Taurine, and Choline, which are vitamins, minerals and amino acids that support the health of neurotransmitters, nerves, muscles, cells, the immune system, the cardiovascular system and more. Product info CeleryForce® gives you a simple way to get important vitamins, minerals, and amino acids that many different and vital parts of your body need to function properly. From healthy neurotransmitter signalling to healthy muscular function to healthy nerve transmission to healthy cellular function and more, CeleryForce® can help. Read on to find out how CeleryForce® can support your health! Celeryforce®: Choline is a member of the B vitamin family that supports cellular health Choline is essential for the production of the neurotransmitter acetylcholine Choline supports healthy nerve transmission and is essential for lipid transport and metabolism Inositol supports healthy cellular function Inositol is essential for healthy neurotransmitter signaling Magnesium is an essential cofactor for over 300 enzyme systems. Magnesium is essential for the function of the mitochondrion and is essential for DNA and RNA synthesis Magnesium is essential for the activation of adenylate cyclase, which is an important regulator of cellular activity and is essential for healthy muscular function L-Glutamine supports the function of a healthy immune system L-Taurine is essential for cellular health and also supports cardiovascular health Non-GMO, Gluten-Free, Kosher, Corn-Free, Soy-Free, Vegan, Paleo No Citric Acid and No Gelatin How to Use Serving: As a dietary supplement, take 1 capsule 15 minutes before or after your celery juice, or at anytime, 1 to 2 times daily. Storage: Store in a cool, dark place. Contraindications Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Immediately discontinue use and consult your doctor if you experience any adverse reaction to this product.
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Vimergy Vimergy Herbs - ULTI-Ashwagandha 10:1 (115ml)
£29.00
Want better brain function? Help for dealing with stress? How about healthy sleep? If you answered yes, Vimergy Organic Ashwagandha 10:1 Liquid Extract is here for you! It contains 2200mg of the adaptogen ashwagandha per serving! Our special alcohol-free formula is made with these organic ingredients: organic ashwagandha 10:1 extract, organic glycerin and organic lemon juice. Product info Ashwagandha is a special herb that acts as an adaptogen in your body, helping you have a healthy response to stress. With all the stresses and challenges life throws at us, some help to cope with it can really go a long way! And that’s not all that ashwagandha has to offer. Ashwagandha can also help your brain and mental functioning and even help you get the sleep you need to feel your best! Organic Kosher Vegan Paleo Gluten Free USDA Organic Alcohol-Free Ashwagandha: Promotes a healthy response to stress Supports healthy cognitive function Promotes healthy sleep Potent 10:1 water extracted alcohol-free formula Created with Organic Glycerin and Organic Lemon Juice only Can be taken by placing it directly in the mouth or add it to water, juice, or a smoothie USDA Organic, Alcohol-Free, Gluten-Free, Non-GMO, Kosher, Corn- Free, Soy-Free, Vegan & Paleo Friendly No Citric Acid, Fillers, Additives, Artificial Flavors or Natural Flavors How to Use Serving: Serving: As a dietary supplement, take 2 dropperfuls (2mL), 1 to 2 times a day. One serving is approximately 48-54 drops.Storage: Store in a cool, dark place.Contraindications: Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Immediately discontinue use and consult your doctor if you experience any adverse reaction to this product.
Vimergy Vimergy Herbs - Magnesium Glycinate 180caps
£35.00
Product info Magnesium is one of the most abundant minerals in the body and plays an important role in a number of critical bodily processes, including DNA / RNA synthesis, cellular health and energy production, and neurological function. It is also an essential co-factor for more than 300 enzyme systems in the body. Vimergy’s Magnesium Glycinate contains 220mg of magnesium per serving and is formulated with special additions of organic ginger and turmeric. Magnesium supplementation has been shown to support healthy cardiovascular and muscle function. Magnesium Glycinate: Magnesium supports healthy cardiovascular function Magnesium supports healthy muscle function Each serving contains 220mg of Magnesium Glycinate, plus organic ginger and turmeric root Non-GMO, Gluten-Free, Kosher, Soy-Free, Vegan, Paleo No Citric Acid and No Gelatin How to Use Serving: As a dietary supplement, take 2 capsules, 1 to 2 times daily.Storage: Store in a cool, dark place.Contraindications: Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Immediately discontinue use and consult your doctor if you experience any adverse reaction to this product.
Vimergy Vimergy Herbs - Magnesium Glycinate 300caps
£50.00
Product info Magnesium is one of the most abundant minerals in the body and plays an important role in a number of critical bodily processes, including DNA / RNA synthesis, cellular health and energy production, and neurological function. It is also an essential co-factor for more than 300 enzyme systems in the body. Vimergy’s Magnesium Glycinate contains 220mg of magnesium per serving and is formulated with special additions of organic ginger and turmeric. Magnesium supplementation has been shown to support healthy cardiovascular and muscle function. Magnesium Glycinate: Magnesium supports healthy cardiovascular function Magnesium supports healthy muscle function Each serving contains 220mg of Magnesium Glycinate, plus organic ginger and turmeric root Non-GMO, Gluten-Free, Kosher, Soy-Free, Vegan, Paleo No Citric Acid and No Gelatin How to Use Serving: As a dietary supplement, take 2 capsules, 1 to 2 times daily.Storage: Store in a cool, dark place.Contraindications: Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Immediately discontinue use and consult your doctor if you experience any adverse reaction to this product.
Vimergy Vimergy Herbs - Magnesium Glycinate 60caps (Trial Size)
£20.00
Product info Magnesium is one of the most abundant minerals in the body and plays an important role in a number of critical bodily processes, including DNA / RNA synthesis, cellular health and energy production, and neurological function. It is also an essential co-factor for more than 300 enzyme systems in the body. Vimergy’s Magnesium Glycinate contains 220mg of magnesium per serving and is formulated with special additions of organic ginger and turmeric. Magnesium supplementation has been shown to support healthy cardiovascular and muscle function. Magnesium Glycinate: Magnesium supports healthy cardiovascular function Magnesium supports healthy muscle function Each serving contains 220mg of Magnesium Glycinate, plus organic ginger and turmeric root Non-GMO, Gluten-Free, Kosher, Soy-Free, Vegan, Paleo No Citric Acid and No Gelatin How to Use Serving: As a dietary supplement, take 2 capsules, 1 to 2 times daily.Storage: Store in a cool, dark place.Contraindications: Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Immediately discontinue use and consult your doctor if you experience any adverse reaction to this product.
Organixx Organixx – Magnesium 7 60caps
£39.95
BENEFITS Helps reduce stress & anxiety levels* Promotes restful & restorative sleep* Supports a healthy heart & strong bones* Enhances nutrient absorption & energy creation* Contributes to healthy cellular & nerve function* Helps maintain muscle mass/power & calms sore muscles* PRODUCT DETAILS Full-Spectrum: 7 types of magnesium Chelated for maximum bioavailability 250mg of magnesium in every capsule With co-factors for absorption: B6 & manganese No magnesium oxide, chloride, hydroxide, sulfate, or stearate Non-GMO; No fillers, preservatives, or additives Magnesium Chelate (Muscle Recovery)Chelated forms of magnesium provide the best absorbency in comparison to non-chelated. Research published by the New York Headache Center3 suggests that 400 mg of chelated magnesium a day is especially helpful for pre-menstrual syndrome and foot and leg cramps. The researchers found that chelated magnesium also helped those who tend to have cold extremities (hands or feet) caused by environment or stress. Magnesium Glycinate (Sleep, Anxiety & Brain Health)One of the most popular forms of magnesium, magnesium glycinate (also known as magnesium diglycinate or magnesium bisglycinate) is a chelated form of magnesium that contains the amino acid glycine. Glycine is the smallest amino acid and is able to cross the blood-brain barrier. It’s best known for benefits relating to sleep and brain health.If you’re looking for the best magnesium supplement for anxiety, magnesium glycinate has been shown to have a soothing effect on the brain5 and several studies have shown that magnesium glycinate may help to calm anxiety. Magnesium Aspartate (Mood, Anxiety & Depression)Magnesium aspartate is a form of magnesium that is bonded to aspartic acid, a non-essential amino acid found in protein-rich foods such as eggs and meat. Aspartic acid is often used by bodybuilders to enhance athletic performance, recovery, and muscle strength. Many users of magnesium aspartate report finding this form one of the best magnesium supplements for leg cramps and other muscle cramping. Magnesium Malate (Brain & Nervous system)Getting enough magnesium through food and supplementation is key to many physiological functions, especially those that effect the brain. Because it’s able to work quickly and is more long-lasting, magnesium malate is considered one of the most beneficial forms for brain and nervous system health and one of the best magnesium supplements for headache – including migraines. Magnesium Orotate (Heart & Exercise Performance) Orotate is a type of magnesium salt that comes from orotic acid and is easily absorbed into the cells. According to some natural health experts, it represents the “absolute best” type of magnesium supplement for health. Some studies also indicate that magnesium orotate may be especially beneficial for the heart and exercise performance, making it a favorite magnesium supplement for athletes. Magnesium Taurate (High Blood Pressure, Relaxation & “Calming the Nerves”) Magnesium taurate is one of the best forms of magnesium for easy assimilation into the body. This is because taurine is used by the body naturally to transport magnesium ions in and out of cells. According to experts, it’s also the supplement that is easiest on the stomach and is also one of the best magnesium supplements for heart health. Magnesium Citrate (Cardiovascular & Intestinal Health) Magnesium citrate is magnesium combined with citric acid. It’s one of the most popular types of magnesium, and according to the National Institutes for Health is also one of the most highly absorbable forms by the body.17 Like all forms of magnesium, it’s vital for a healthy heart, muscles, and bones. It’s also required for RNA and DNA synthesis and for the production of glutathione, the master antioxidant. Vitamin B6 (Pyridoxine Hydrochloride) (Combined with Magnesium Improved Stress Reduction by 24%) In research studies, the complementary effects of vitamin B6 and magnesium taken together has shown greater benefit than magnesium alone for treatment of severe stress and symptoms associated with PMS such as irritability, mood swings, and anxiety. For instance, one 2018 study20 reported a 24% stronger stress reduction among participants with “severe/extremely severe stress” who took both magnesium and B6 compared with just magnesium.Interestingly, the B6 and magnesium combination has been found in other studies to have a significant and positive behavioral benefit for children with Autism Spectrum Disorder (ASD) and ADHD.21 Manganese Citrate (Bone Strength) Manganese is an essential trace mineral involved in dozens of functions and chemical processes in the body including bone formation, healthy blood sugar management, and metabolism. It’s also a major antioxidant. Manganese is necessary for the proper functioning of the nervous system, the brain, and many key enzymatic reactions in the body.
Bulletproof Bulletproof - Sleep Mode - 60 Caps
£26.95
Take one serving (two softgels) 30 minutes before bed to sleep like a baby and perform like a rock star. Amount Per Serving (2 Softgels): Brain Octane® oil – 500mg Plant-sourced, Bio-identical Melatonin – 0.3mg (300mcg) L-Ornithine – 400mg  Other Ingredients: Gelatin, glycerin, sunflower lecithin, silicon dioxide, purified water, zinc oxide, curcumin. Herbatonin® is the registered trademark of NHI, Inc. Benefits: Complete support for efficient, restful sleep Relieves stress to help you relax and fall asleep Supports stable energy during sleep Description: 1 bottle of 60 Softgels Contains plant-sourced, bio-identical melatonin Thanks to always-on technology, light pollution and everyday stress, it can be harder than ever to wind down and get the kind of truly refreshing, restorative sleep you need for peak performance the next day.  Enter Bulletproof™ Sleep Mode™ — a complete solution engineered to help you fall asleep faster and get the most efficient night’s rest possible, night in, night out. After all, while many sleep supplements out there focus solely on getting you to sleep — your energy during the day depends just as much on how much time you spend in actual restorative sleep throughout the night, rather than tossing and turning or staring at the ceiling.  Bulletproof Sleep Mode combines ingredients shown to have unique effects of relieving stress, strengthening a normal pattern of sleep, and increasing the time you spend in actual restorative sleep. The Ingredients For The Perfect Night’s Sleep Melatonin is a natural hormone released in the absence of light that quickly crosses the blood-brain-barrier to support your circadian rhythm and help you fall asleep.  It’s an ingredient commonly found in many sleep supplements at higher doses, but too much melatonin can leave you with an unnatural spike of melatonin into the next day. Given that melatonin is released to promote sleep onset, having elevated levels in your blood plasma during the day from taking higher doses at night may not be ideal. That’s why Bulletproof Sleep Mode contains a 0.3mg physiological dose of melatonin supported by scientific research — just enough to boost sleep efficiency, the time where you are getting your best restorative sleep.  Plus, unlike the vast majority of melatonin on the market — which are either extracted from animal pineal glands or artificially created in a lab — the bio-identical melatonin in Sleep Mode is 100% plant-sourced from Herbatonin®. To help you beat stress and power down for the night, Bulletproof Sleep Mode also contains L-Ornithine— an adaptogenic amino acid that lowers the stress marker cortisol (again, you’re getting the precise clinically studied dose of 400mg suggested by the latest scientific studies) and strengthens a normal sleep pattern.  And finally, to help maintain consistent energy during sleep — when your body is working hard to repair muscle, consolidate memory, release growth and appetite hormones, and other critical tasks — Sleep Mode contains Bulletproof Brain Octane® oil to keep you going with hyper-efficient ketone fuel.  You are now entering Sleep Mode — power down, charge up! This Is Your Edge Bulletproof™ supplements are backed by the most cutting-edge research, science, and technology to kick performance into overdrive. Sourced from the best, most bioavailable ingredients possible — all Bulletproof supplements are 100% non-GMO, soy, and gluten-free, with no artificial colors, added preservatives, or any other junk. They undergo strict lab testing to ensure they meet the rigorous quality standards of the Bulletproof Process™ — ensuring purity and potency. So you can focus on being more awesome, in every way.  Herbatonin® is the registered trademark of NHI, Inc.
-21% sale
Activation Activation - Magnesium Ease 250ml
£31.00 £39.00
Did you know that magnesium is an essential mineral that is required by virtually every cell in your body?  Perhaps the most high-profile process that magnesium is used for is metabolising nutrients and turning them into energy. EASE Magnesium is a natural solution that enters your bloodstream through your skin to help fulfil your magnesium needs. It does not cause stinging, burning or itching and will not leave a sticky residue on the skin. Benefits Did you know that magnesium, an essential mineral that is required by virtually every cell, is especially important to muscles? Magnesium is an essential building block for hundreds of chemical processes in the body. Your muscles’ ability to contract and relax is highly dependent on how much magnesium your body is getting. Other things affected by magnesium include: Nerve function Cardiac activity Blood pressure regulation Hormonal interactions Bone health Synthesis of proteins, fats and nucleic acids Additionally: It is the fourth most abundant mineral in your body Exists in over 300 different bodily enzymes Is found primarily in your bones (half of your total body magnesium) Plays a role in your body’s detoxification processes Aids your energy metabolism and protein synthesis Helps guide a large number of physiological functions Is required by glutathione (the “master antioxidant”) for synthesis   Is especially valuable for supporting your brain health The list goes on. The bottom line is that magnesium is the multi-tasking mineral your body needs and is probably not getting enough of. Perhaps the most high-profile process that magnesium is used for is metabolising nutrients and turning them into energy. Magnesium activates enzymes which help produce something called ATP (adenosine triphosphate). Why is ATP important? ATP plays a crucial role in the metabolic process. When your body breaks down ATP, the energy that is released is used by your muscles. The more you exercise and the harder you exercise, the faster your body burns up the energy released from breaking down ATP. If you’re not getting enough magnesium, it can result in low energy levels and problems with muscle function. Additional Information Are you deficient? Did you know up to 80% of people are magnesium deficient? And that is just the people showing symptoms of deficiency. Magnesium deficiency is currently deemed a "silent epidemic", as often it's effects are not felt until very advanced and difficult health conditions have already developed. How is it that so many people are not getting enough from their diets or are having trouble absorbing what they do eat? It’s an important question. If magnesium deficiency gets out of hand it can lead to all kinds of serious health issues. Below is a short list of some of the factors that can cause magnesium deficiency: Regularly drinking caffeinated beverages, soda or alcohol - Sodas contain phosphates that attach themselves to the magnesium inside your body, making it unavailable for absorption. Plus, your kidneys filter and excrete excess magnesium and other minerals as part of their normal function. Taking calcium supplements - Women should be especially wary of the effects of certain supplements on magnesium absorption. If you have been instructed to take a calcium supplement to prevent bone loss or to treat osteoporosis, this could be the reason for low magnesium levels. Experiencing constant or chronic stress - The Nutritional Magnesium Association website cites a study that investigated chronic stress and magnesium levels. It was found that chronically stressed individuals had lower magnesium stores when compared with control groups. On the flip side, those who had sufficient magnesium in their systems exhibited fewer signs of stress. In other words, stress causes magnesium loss while, at the same time, getting adequate magnesium protects against stress. How to get Magnesium? Ease is the purest, fastest acting form of bio-available magnesium available.  Absorbed directly through your skin delivering a calming energy that your body needs. This powerful supplement is easily absorbed into the skin, enters the blood stream and goes directly to work in your body, affecting aches and pains, helping to support the nervous system and reducing fatigue leaving you feeling revitalised, supple and full of beans. Delivers 27.2mg of magnesium per spray Fast acting magnesium  100% pure solution Why a spray? Oral magnesium supplements are known to have poor absorption rates and may cause diarrhea and other gastrointestinal problems in larger doses. One of the big benefits of a magnesium spray is how effectively it is absorbed when it’s sprayed onto the skin. By bypassing the digestive system it goes straight into the bloodstream and is delivered to the cells that need it. Suggested Use 30-50 sprays on wrists, tops of the feet, underarms, backs of knees and hips. Ingestion not recommended. Best absorbed after a hot shower or bath. Shelf-Life/Storage Instructions Keep bottle capped and store in a cool, dry place, out of direct sunlight. When stored properly, spray will remain fresh for 36 months. Ingredients Purified water and pharmaceutical grade magnesium chloride hexahydrate. 100% pure iMCH.
WAM Essentials (Dr Wong) Magscorbate™ 90 Caplets (WAM Essentials)
£27.95
Dr. Wong's Newly Formulated Magnesium Product is Now In-Stock and Available for Immediate Shipping!  Magnesium is an essential mineral nutrient for life. It is present in every cell type in every organism and is vital to the well being of all organisms.* Adult human bodies contain about 24 grams of magnesium, with 60% in the skeleton, 39% intracellular (20% in skeletal muscle), and 1% extracellular. ATP (adenosine triphosphate), the main source of energy in cells, must be bound to a magnesium ion in order to be biologically active.* Over 300 enzymes require magnesium ions in order to function*. Magnesium in one of its various forms (ie: gluconate, malate, orotate, magnesia, citrate etc) can be found in common laxatives, antacids (i.e., milk of magnesia), and can be used in a number of situations where stabilization of abnormal nerve excitation and blood vessel spasm is required.* The average adult human daily nutritional requirement is set to 300-400 mg per day of elemental magnesium. Inadequate magnesium intake frequently causes muscle spasms, and has been associated with cardiovascular disease, diabetes, high blood pressure, anxiety disorders, migraines, osteoporosis and cerebral infarction[1]*. Human magnesium deficiency (including conditions which show few overt symptoms) is relatively common, with only 32% of the United States meeting the RDA-DRI,[2] and has been implicated in the development of a number of human illnesses such as asthma, osteoporosis, and ADHD.[3]* Due to its basic struction/function, magnesium may effect muscle relaxation through direct action on the cell membrane.* With the addition of magnesium, more channels may be blocked and the nerve may have less activity which could help support the body in reducing the itching/crawling sensations commonly noticed during periods of rest or sleep.* According to a randomised, double-blind study, done in 2003, scientists found Magnesium citrate to be more bioavailable than oxide or amino-acid chelate (glycinate) forms[4].*  We have blended our own “chelated” magnesium using just enough Vit. C (345 mg) to assure good absorption of the mineral, while providing the full load of elemental mineral stated on the label: 510 mg of magnesium.    We chose to use the more expensive Vit. C instead of the cheaper citric acid as the chelating agent because Vit. C has health benefits to your body that citric acid does not have. Now to answer the question:  Why did we use Magnesium Oxide in our product?  What folks don't understand that Dr. Wong has taught in his shows is that the elemental magnesium in all chelated mag products is magnesium oxide!    All chelated minerals are a blend of the mineral source and the chelating agent.   The chelating agent is always cheaper than the mineral source so they put in a lot of that and little mineral. The industry standard would look like this: 85% citric acid and only 15% magnesium oxide (for magnesium citrate as an example) References:1. Larsson SC, Virtanen MJ, Mars M, et al (March 2008). "Magnesium, calcium, potassium, and sodium intakes and risk of stroke in male smokers". Arch. Intern. Med. 168 (5): 459–65. doi:10.1001/archinte.168.5.459. PMID 18332289.2. "Lack Energy? Maybe It's Your Magnesium Level". United States Department of Agriculture. Retrieved on 2008-09-18. Last paragraph3. University of Maryland Medical Center. Magnesium 4. Walker AF, Marakis G, Christie S, Byng M (September 2003). "Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study". Magnes Res 16 (3): 183–91. PMID 14596323. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.    
Natural Stacks MagTech™ Complex: 90 Capsules (Natural Stacks)
£34.95
As a necessary component of over 325 biochemical reactions, magnesium is one of the most important essential nutrients for maintaining optimal health and performance.  Magnesium plays a role in vital processes such as protein syntheses, cardiovascular health, immune function, and blood sugar management. Specific to the brain, magnesium promotes healthy neuronal activity for supporting recall, learning, decision making, and spatial recognition. It’s impossible to achieve optimal mental and physical performance without maintaining proper levels of magnesium. Unfortunately, magnesium is one of the most deficient minerals in the American diet. In fact, the percentage of the U.S. population deficient in magnesium could be as high as 80%.  Deficiency can lead to “brain fog” and disease. INTRODUCING MAGTECH™ - THE OPTIMAL MAGNESIUM COMPLEX MagTech™ is a premium blend of all three different types of magnesium known to have the highest absorption, Magtein Magnesium L-Threonate, Magnesium Taurate, and Magnesium Glycinate. Each compound is fully chelated for optimal absorption and effectiveness.  “Chelated” means that the magnesium is bonded to an amino acid.  Chelation is the body’s natural means to transport minerals across the intestinal wall as part of digestion, so chelated magnesium is far better absorbed than most supplements which are cheap magnesium salts. MagTech™ has 100% nutritional density, meaning that all components of the magnesium complex have true nutritional value. We carefully chose forms of magnesium that are chelated with nutritionally functional amino acids, each with a specific role to optimize mental and physical performance. Magtein™ Magnesium L-Threonate & Synapse Density The human brain has about 100,000,000,000 neurons that communicate with each other through synaptic connections. Each individual neuron is capable of having thousands of synapses, leading to trillions of synaptic connections in the brain. These connections create neural networks that form the foundation for higher cognitive functions like learning, memory, and emotional regulation. The more synaptic connections you have, the better your memory, the faster your brain processes information, and the better your attention and focus will be. A breakthrough discovery at MIT demonstrated the key role that magnesium plays in regulating synapse density. The team of scientists showed that increasing magnesium levels in the brain leads to a significant and lasting increase in the number of functional synapses. However, the scientists found that conventional magnesium supplements were very poorly absorbed and failed to elevate magnesium in the brain, so they developed Magtein™. Magtein™ is a proprietary magnesium compound specifically designed to increase brain magnesium levels.  It is a form of magnesium that is chelated to L-threonate (a metabolite of vitamin c) to act as a carrier to facilitate magnesium’s entry into the brain.    Magtein™ (magnesium l-threonate) has been shown to significantly increase the brain’s number of synaptic connections / synaptic density (see graph on the left), and enhance both short-term and long-term memory (see graph on the right). Magnesium Taurate & Neurotransmitter Balance Magnesium taurate delivers an important amino acid, taurine to the brain and body.  Magnesium and taurine have synergistic and potentiating roles. Magnesium and taurine work together to stabilize cell membranes throughout the central nervous system and maintain neurotransmitter balance. One of taurine’s main tasks is to facilitate the passage of sodium, potassium, and magnesium ions into and out of cells for optimal neuronal activity. Taurine has a role in vision, cardiac health, bile production, as well as muscle growth.  It also acts as an antioxidant, inhibiting LDL cholesterol oxidation. Magnesium Glycinate & Sleep Quality Magnesium glycinate is a highly bioavailable form of magnesium and a significant source of glycine, an amino acid that promotes deep sleep and the elimination of toxins from the body. Magnesium and glycine both have a calming effect on the brain, helping to reduce stress and increase sleep quality. Restful sleep is important for the restoration of energy stores in brain cells depleted during a full day of thinking.  And with it’s anti-inflammatory properties, glycine is beneficial to the entire recovery process. Glycine has been shown to improve memory retrieval and reduce fatigue in individuals with sleep-depriving conditions, including jet lag and overwork. As an essential component in the synthesis of creatine, glycine also helps preserve muscle mass and prevent liver damage.  It plays a key role in liver detoxification by increasing glutathione. Accelerate your mind with    Suggested Use: Take 2 servings per pay, preferably 1 serving in the afternoon and 1 serving in the evening, or as directed by a healthcare practitioner. U.S.A manufactured in a GMP facility. Natural Stacks proudly uses only the highest quality ingredients. Magtein™ Magnesium L-Threonate Built on over a decade of research, scientists from MIT (including a Nobel Prize laureate) developed the revolutionary new compound Magtein™ (magnesium l-threonate) to increase the levels of magnesium in the brain for optimal mental function, memory, and sleep.    "Magtein™ is a trademark of Magceutics, Inc. and is distributed exclusively by AIDP, Inc. Magtein is covered by registered and pending U.S. Patents." Magnesium Taurate Magnesium Taurate is a synergistic combination of magnesium and taurate, a free-form amino acid.  It’s known to decrease anxiety, relieve muscle fatigue, and promote a stronger immune system. This form of magnesium supports maximum absorption in the cells and distribution throughout the body. Magnesium Glycinate Magnesium glycinate has a positive impact on attention, memory, and stress reduction. Utilizing the essential amino acid glycine, this form of magnesium has a calming effect on the brain and promotes deeper sleep. Magnesium L-Threonate: In a recent rodent study, top neuroscientists from universities in Beijing, Texas, and Toronto found that “elevation of brain magnesium, by a novel magnesium compound [magnesium-l-threonate (MgT)], enhances synaptic plasticity in the hippocampus and learning and memory” [1] Twelve scientists at MIT conducted a study on magnesium-L-threonate and concluded that “an increase in brain magnesium enhances both short-term synaptic facilitation and long-term potentiation and improves learning and memory functions.” [2] A study using magnesium-L-threonate to treat Alzheimer’s Disease discovered that “Elevation of Brain Magnesium Prevents and Reverses Cognitive Deficits and Synaptic Loss” [3] In early 2014, two human studies on magnesium-L-threonate will be released to the public. Taurine (found in Magnesium Taurate): Researchers at Tufts University found that "Taurine increased choice reaction time" and "Taurine reversed the effects of caffeine-withdrawal symptoms" [4] A recent study on taurine's neuroprotective properties concluded that taurine supplementation "significantly ameliorated the age-dependent decline in spatial memory acquisition and retention" and can "forestall the age-related decline in cognitive functions". [5] In Japan, a study of 25 male college students found that "taurine supplementation alleviates visual fatigue induced by visual display terminal (VDT) work" [6] Glycine (found in Magnesium Glycinate): A 2012 study on healthy male volunteers found that "glycine improves daytime sleepiness and fatigue induced by acute sleep restriction" [7] A study on individuals with continuous complaints about the quality of their sleep concluded that "glycine ingestion significantly improved the following elements: 'fatigue', 'liveliness and preppiness', and 'clear-headedness'." [8] When studying the effects of glycine ingestion before bedtime on volunteers who have been experiencing unsatisfactory sleep, scientists in Japan found that it "improved the volunteers' satisfaction with their sleep, the difficulty of sleep onset, and sleep efficiency" [9] Sources: http://www.ncbi.nlm.nih.gov/pubmed/22016520 http://www.ncbi.nlm.nih.gov/pubmed/20152124 http://www.ncbi.nlm.nih.gov/pubmed/23658180 http://www.ncbi.nlm.nih.gov/pubmed/22819803 http://www.ncbi.nlm.nih.gov/pubmed/23963537 http://www.ncbi.nlm.nih.gov/pubmed/14752617 http://www.ncbi.nlm.nih.gov/pubmed/22529837 http://onlinelibrary.wiley.com/doi/10.1111/j.1479-8425.2006.00193.x/abstract http://onlinelibrary.wiley.com/doi/10.1111/j.1479-8425.2007.00262.x/abstract
Cymbiotika Cymbiotika - Magnesium L-Threonate 30 pouches
£56.95
Benefits Magnesium L-Threonate may help with the following: Boost brain power Balance mood and calm central nervous system Improve memory PRO-TIP:  Support overall brain health by taking with Cymbiotika's Golden Mind. Description Cymbiotika’s Liposomal Magnesium L-Threonate was developed by a team of scientists at MIT which has been shown to increase brain magnesium levels much higher than any other form of magnesium. Magnesium is an essential mineral that is required for 80% of the body’s metabolic functions. In the United States, approximately 65% of all adults are magnesium deficient.  Magnesium deficiency contributes to many chronic conditions including heart disease and loss of cognitive function. How to Enjoy 1 pouch (10 mL) daily* Squeeze entire contents of pouch directly into mouth or stir into your favorite beverage. Store in a cool, dry place away from direct sunlight. *To be used as directed by your healthcare provider or physician. Disclaimer: If you are pregnant, nursing a baby, or have a chronic medical condition, such as, diabetes, hypertension or heart disease, be sure to consult your doctor or pharmacist before purchasing or taking any supplement. Ingredients Magnesium (from 1,300mg of Magtein® Magnesium L-Threonate), Phosphatidylcholine, Vitamin E (as D-Alpha Tocopherol) Other Ingredients: Glycerin, Purified Water, Organic Almond Butter, Organic Coconut Nectar, Organic Almond Oil, Organic Vanilla Extract, Konjac Root, Celtic Sea Salt, Organic Citrus Extract
Nutrasal Nutrasal Magnesium + L-Arginine Cream 8oz (226g)
£32.95
Now Made with Dead Sea Magnesium Magnesium, L-arginine Cream is a smooth, quickly absorbed liposomal preparation of magnesium chloride, and L-arginine in a nourishing and moisturizing base of organic aloe, coconut oil and essential oils. The cream is fragrance free and does not contain artificial preservatives. Product Information Topically applied, magnesium may restore cellular magnesium levels, act as a cellular protectant, support detoxification, sooth aches and pains, and relieve stress.Topically applied L-arginine may help blood flow and circulation, especially in the hands and feet, as well as other sensitive areas for both men and women. ** Transdermal applications are recommended at just 5% of the recommended oral dose. Nutrasal applies over 30 years of experience and advanced pharmaceutical grade phospholipid technologies to create exceptional Liposome Delivery Systems (LipoZome� ) to apply to sublingual sprays, liquids, and topicals. Our pharmaceutical grade phospholipids and proprietary liposomal process combine to significantly enhance the absorption of active ingredients when taken orally, or applied topically to the skin. Our liposome encapsulated active ingredients are rapidly absorbed into the mucosal tissue of the mouth, and penetrate deep into the skin. The active ingredients are readily absorbed into the bloodstream and are able to circulate throughout the body in minutes.   LipoZome� technology can be used to convert conventional pills and tablets, into liquids, sublingual sprays, and topical applications, thereby enhancing Tmax and Cpmax and overall bioavailability. The result is enhanced therapeutic outcomes as compared to conventional dosage forms that travel through the digestive tract. Liposomes have been known within the scientific community for decades as effective carriers of biologically active ingredients used to target specific sites of action. Nutrasal�s unique and versatile LipoZome� Active Delivery Systems are a next generation liposome that can be used for a variety of applications in OTC drug products, cosmetic, personal care, and dietary supplements.
RDT Formulas RDT Formulas - Dream 100g Bag (not in jar)
£46.00
*We have decided to only stock these in stand up pouches to prevent breakages from international shipping.* DREAM Peaceful sleep Gentle Wake up refreshed Not habit forming Not tranquilizing    DREAM is composed of herbs that help us drift into “twilight revelry,” where myriad dream images begin to settle our conscious thoughts, our worries, and our ambitions. Zizyphus, the roasted seed of the jujube fruit, gently nourishes relaxation and helps relieve anxiety. Scutellaria is revered for relaxing our nerves. Pearl is “grounding.” Polygonum stem also helps guide us into sleep state with a sense of safety. Albizzia flower is said to calm the heart. White peony root releases restless, pent-up energy, L-theanine is a well-known amino acid that promotes sleep, and Polygala is called the “will strengthener.”  DREAM is a true ally promoting calm sleep without causing grogginess the following day. It is not habit forming. A cup taken 30 minutes before bed makes a pleasant tasting night-time tonic. Use only as directed. Enjoy peaceful dreams! Directions 30 minutes before bedtime, take 1 slightly rounded teaspoonful in a cup of hot water. May add vegan milk and sweetener to taste. Over a few nights, you can adjust the amount you need for a restful, peaceful sleep. Ingredients Zizypuus, Reishi, White peony root, Polygonum stem, Scutellaria, Albizzia flower, Lohan quo, Bamboo, Polygala,  Schizandra, Pearl, L-Theanine, ORMUS The majority of Tonic herbs are wild plants, harvested in forests in an ancient tradition by sanctioned collectors. Great care is taken to insure the herbs are gathered sustainably, with minimal damage to the environment. Rehmannia sources his herbal powdered extracts from pristine regions in the northern Manchurian province of China, as well as the Korean countryside. This region is geographically similar to Maine, hosting many protected biospheres which are monitored by the United Nations and the Chinese government. The herbs selected from these wild forests are designated “Di Tao,” meaning they are guaranteed pure, and sustainably collected from the region of their biological origin. We provide lab analysis (COA’s) upon request.
Mineralife Zemvelo - MAGNESIUM 240ml / 8floz (previously Mineralife)
£20.99
The Key to Optimal Health Zemvelo Magnesium is derived from ancient Permian Sea deposits. Untouched by the environment, these deposits have been deep below the surface of the earth for many, many years. This means that they are in a pure, natural form, making them the best minerals for our customers. Furthermore, a liquid ionic magnesium supplement is easy to take and provides superior absorption and utilization in your body to ensure optimal health. Zemvelo Liquid Magnesium is also complexed with CHD-Fulvic Acid to further increase absorption and enhance overall wellbeing. CHD-Fulvic Acid can naturally support the body’s immune, inflammatory, and detoxification response. Invest in your health with Zemvelo Magnesium today. TRACEABLE INGREDIENTS How to Use Magnesium Mix half a teaspoon with water or your favorite juice and drink up! This supplement can be taken on its own if you prefer. If you are new to taking magnesium it can be helpful to start with half a serving and work your way up to a full serving. Listen to your body when you are beginning to nourish it and, as always, reach out to us at customerservice@zemvelo.com if you have any questions! Active Ingredients Zemvelo’s liquid ionic magnesium supplement provides superior absorption and utilization in your body to ensure optimal health. MINERAL SOURCE Zemvelo’s Magnesium comes from the Permian Basin, Texas, USA. Form: Magnesium Chloride Found in: Almonds, cashews, soybeans, grains, leafy vegetables, cocoa Manufactured in: Tulsa, OK, USA. FEATURES Clinically tested professional grade CHD-Fulvic Acid has been added to Zemvelo’s Magnesium to further increase absorption and enhance overall well-being as fulvic acid can naturally support the body’s immune, inflammatory, and detoxification response. Pure – Derived from pure, ancient Permian Sea deposits Concentrated – 40,000 PPM or mg/L Excellent Value – 96-day supply FACT FILE Magnesium is involved in 300+ processes within your body. Deficiency can lead to unwanted side effects. Magnesium encourages healthy digestion, sustained energy, better sleep, and overall, less physical and mental uneasiness. Magnesium works closely with calcium to support healthy bones and joints in your body! Magnesium can aid in muscle recovery as well as decrease the frequency of involuntary muscle movement. Liquid Ionic Magnesium Benefits Magnesium is a powerful, natural mineral. It aids in relaxing nerves, relieving tension, and normalizing blood pressure. Magnesium is a vitally important nutrient for humans that is required for many biologic functions, including over 300 enzymatic reactions. Facilitates calcium transport and deposition into bone and blood vessels throughout the body. Supports tissue growth and development. Supports immune system health and function. Is a primary electrolyte along with calcium, potassium, sodium, and chloride. Supports airway health and respiration. Helps conduct nerve impulses and the relaxation of muscle tissue. Supports healthy and normal involuntary body movements. Supports healthy and proper growth. Supports muscle health. Supports healthy and happy disposition. Supports healthy eating habits. Supports monthly feminine health. supports healthy cardiovascular electrical impulses. What is Ionic Magnesium Used For? Zemvelo Magnesium to Balance Mood Many of us are under constant stress, whether it be physical, emotional, or mental. Stress, of all forms, wears down your body. Too much stress can sometimes lead to disease. Magnesium is a powerful natural tranquilizer that relaxes the nerves, relieves tension, and lowers blood pressure. So, it can help you relax, physically and mentally, and promote healthy cardiovascular function in the process! Magnesium for Graceful Aging Incorrect magnesium to calcium ratio results in a rapidly aging body. Magnesium can assist people in enjoying the prime of their lives by promoting ease of joint movement, steady functioning of the cardiovascular system, proper sugar balance, healthy bones, and long-term mental clarity. Ionic Magnesium Because magnesium is so important for our bodies, magnesium deficiency can increase the frequency of physical discomforts, from headaches to muscle cramps, or negatively affect regularity, energy, and sleep. Alcohol and caffeine can also deplete your magnesium stores. Both caffeine and alcohol can be considered diuretics, increasing the amount of water flushed from the body. When this happens, important electrolytes, including magnesium, are flushed. To replenish your body with important electrolytes, taking them in ionic form is going to help with ultimate absorption. It’s all about balancing your nutrition program to fit your lifestyle. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sold out -26% sale
The Energy Blueprint Human Optimization - Sleep 120 Capsules
£44.00 £59.00
Is It Memory Loss?   Or sleep loss? Lack of sleep can lead to... Impaired memory [1] Decreased cognitive ability [2] Poor mood [3] Imbalanced immune function Increased risk of infectious disease [4] Vascular inflammation Increased risk of cardiovascular disease [5] Higher risk of sarcopenia - involuntary loss of muscle mass [6] Emotional dysregulation [7] Low libido [8] Cravings & weight gain [9] Metabolic syndrome [10] Hormonal imbalances [11] Decreased fertility & ability to conceive [12]     "In addition to elevated risks of chronic diseases, short sleep duration is strongly associated with decreases in cognitive performance... ...impairments in several cognitive domains can be observed even after short-term sleep restriction" [13]. Nature Journal, October 2021       Add 4 Pills To Your Night...And Extra Years To Your Life. Sleep deprivation has deadly consequences, especially for women. You might feel tired today, but over time, your health takes an enormous hit. The most impactful illnesses and disasters of the 21st century are linked to lack of sleep. Incredibly, a follow-up investigation of the space shuttle Challenger disaster named staff sleep loss as a possible cause [14]. The risk of obesity, metabolic syndrome, hypertension, heart attack, stroke, Alzheimer’s disease, and cancer, particularly the increasingly prevalent colorectal cancer, increase with suboptimal sleep [15, 16]. And women are affected more than men. Females with disturbed sleep have greater chances of cardiovascular disease, increased insulin, hypertension, and inflammation compared to males [17]. Mental health also suffers—symptoms of depression, anxiety, psychosis, and stress perception worsen with sleep loss. Those with insomnia, for instance, have a two-fold risk of developing depression compared to those without the condition [18, 19].     Imagine 8 Restful Hours Instead Of 5 Restless Ones. A Calm Mind Instead Of Racing Thoughts. The best part? No Rx hangover. Human Optimization Lab's Sleep may support: Non-habit forming REM sleep without the side effects of Rx drugs [20] Healthier balance of non-REM and REM sleep patterns [21] Sounder sleep versus waking up tired before your alarm clock [22, 23] Increased sleep time [22] Faster transition from awake to asleep—no more tossing & turning [22] Alleviation of insomnia, specifically related to age [22, 24, 25] Less chance of waking during the night [26] Reduced symptoms of restless legs syndrome [27] Antioxidant balance and anti-inflammatory effects [28] Reduced anxiety [29] Healthier circadian rhythms, even in the presence of unavoidable light at night [30] Production of your body's own master antioxidant, melatonin [31] Fewer obsessive thoughts that keep you awake [32]     Sleep's dream team: Melatonin & your mitochondria When you think of antioxidants, what comes to mind? Most of us imagine berries, dark chocolate, or vitamins C and E. But the real antioxidant all-star? Melatonin. Melatonin is an incredibly potent and unique antioxidant. Why? Unlike other antioxidants, it's created by your mitochondria and plays enormous roles in optimizing their function...and your energy levels [33].     Ingredients Based On Science, Not Social Media. Sleep is formulated with nutrients and doses proved effective in scientific studies…and only those nutrients. We don’t believe in proprietary blends or hidden excipients. Learn more about our transparent, evidence-based ingredients.     Magnesium (Magnesium Glycinate) Magnesium aids sleep in multiple ways, yet aging is a risk factor for magnesium deficiency. Magnesium relieves muscle tension [35] and is an N-Methyl-D-aspartic acid (NMDA) antagonist and GABA agonist, meaning it gently reduces neuronal excitability and promotes neuronal relaxation.     Potassium (Potassium Glycinate) Sleep is divided into two phases, non-rapid eye movement (NREM) and rapid eye movement (REM) and five separate stages! This organization is called sleep architecture, and potassium is best known for supporting these patterns thanks to its role in regulating the intricate physiology of potassium channels in the nervous system [36].     B6 (Pyridoxal 5’-Phosphate) Pyridoxal 5′-phosphate (PLP), the biologically active form of vitamin B6, is a cofactor for kynurenine aminotransferase (KAT) and kynureninase (KYNU), two key enzymes in the conversion of kynurenine to tryptophan [38]. In turn, we use tryptophan to make both serotonin and melatonin [39].     Herbatonin® (Plant Melatonin) Does melatonin leave you feeling drowsy throughout the morning? Interestingly, a double-blind, placebo-controlled study from MIT found 0.3 mg of melatonin to be the ideal dose for people with insomnia over 50 [24]. When compared to the pharmacological dose of 3 mg, the 0.3 physiological dose restored sleep efficiency without remaining elevated into the daytime.     L-Theanine L-theanine is a non-protein amino acid abundant in green tea, well known for its relaxing effects and ability to cross the blood-brain barrier [40]. Once in the brain, l-theanine blocks glutamate receptors and enhances GABA and dopamine, resulting in reduced neuro-excitability and increased feelings of relaxation [41].     L-Tryptophan L-tryptophan is an essential amino acid that plays an integral part in nervous system health and is the precursor to serotonin, a key hormone for mood regulation (43). Clinical studies of tryptophan-deficient diets show that low intake of this essential amino acid results in increased depression, anxiety, and poor emotional processing [44].     L-Serine L-serine is a non-essential amino acid studied for its remarkable neuroprotective effects [47]. Researchers have hypothesized that dietary L-serine may be responsible for the large centenarian population in Ōgimi, Okinawa, due to their exceptionally high intake of L-serine through foods such as seaweed, tofu, and pork. [48]. The average Ōgimi woman eats over 8 grams of dietary L-serine daily, while her American counterpart only gets 2.5 grams [49].     5-HTP 5-HTP is an amino acid produced from tryptophan and is a metabolic intermediate to serotonin and melatonin. 5-HTP has been studied for its anti-depressant, anxiolytic, and sleep-promoting effects. Several neurodegenerative diseases have been associated with low levels of 5-HTP, including Parkinson’s, fibromyalgia, and Alzheimer's [54].     Myo-Inositol Myo-inositol is a fascinating but commonly underconsumed compound primarily found in organ meats. It was once considered a B vitamin, but its classification changed when endogenous creation from glucose was discovered in the kidneys, liver, and brain.     Chamomile Extract (Matricaria Recutita) For hundreds of years, chamomile has been one of the most trusted, aromatic sleep herbs. It's properties include anti-anxiety, stress relieving, and anti-insomnia. It's also beneficial to the immune and digestive systems and the liver [60]. What people say about Sleep     I have struggled with sleep most of my life, and for the last 10 years have tried many different supplements after finally stopping all sleep medications. Some of these supplements have helped, but I have been using Sleep and find that it combines all the different supplements I have tried into one! It works beautifully, it not only helps me ease into sleep quickly, but when I wake in the middle of the night, I can fall back to sleep. I wake up feeling relaxed but not groggy. I am loving this supplement!!   References Peng Z, Dai C, Ba Y, Zhang L, Shao Y, Tian J. Effect of Sleep Deprivation on the Working Memory-Related N2-P3 Components of the Event-Related Potential Waveform. Front Neurosci. 2020;14:469. Alhola P, Polo-Kantola P. Sleep deprivation: Impact on cognitive performance. Neuropsychiatr Dis Treat. 2007;3(5):553-567. Triantafillou S, Saeb S, Lattie EG, Mohr DC, Kording KP. Relationship Between Sleep Quality and Mood: Ecological Momentary Assessment Study. JMIR Ment Health. 2019;6(3):e12613. Garbarino S, Lanteri P, Bragazzi NL, Magnavita N, Scoditti E. Role of sleep deprivation in immune-related disease risk and outcomes. Commun Biol. 2021;4(1):1304. Hijmans JG, Levy M, Garcia V, et al. Insufficient sleep is associated with a pro-atherogenic circulating microRNA signature. Exp Physiol. 2019;104(6):975-982. Li X, He J, Sun Q. Sleep Duration and Sarcopenia: An Updated Systematic Review and Meta-Analysis. J Am Med Dir Assoc. 2023;24(8):1193-1206.e5. Saghir Z, Syeda JN, Muhammad AS, Balla Abdalla TH. The Amygdala, Sleep Debt, Sleep Deprivation, and the Emotion of Anger: A Possible Connection?. Cureus. 2018;10(7):e2912. Kalmbach DA, Arnedt JT, Pillai V, Ciesla JA. The impact of sleep on female sexual response and behavior: a pilot study. J Sex Med. 2015;12(5):1221-1232. Greer SM, Goldstein AN, Walker MP. The impact of sleep deprivation on food desire in the human brain. Nat Commun. 2013;4:2259. Chasens ER, Imes CC, Kariuki JK, et al. Sleep and Metabolic Syndrome. Nurs Clin North Am. 2021;56(2):203-217. Beroukhim G, Esencan E, Seifer DB. Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review. Reprod Biol Endocrinol. 2022;20(1):16. Kloss JD, Perlis ML, Zamzow JA, Culnan EJ, Gracia CR. Sleep, sleep disturbance, and fertility in women. Sleep Med Rev. 2015;22:78-87. Csipo T, Lipecz A, Owens C, et al. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021;11(1):20994. Mitler MM, Dement WC, Dinges DF. Sleep medicine, public policy and public health. In Kryger MH, Roth T, Dement WC (eds). Principles and Practice of Sleep Medicine, 3rd Edition, Philadelphia: WB Saunders, 2000;580-588. Medic G, Wille M, Hemels ME. Short- and long-term health consequences of sleep disruption. Nat Sci Sleep. 2017;9:151-161. Sabia S, Fayosse A, Dumurgier J, van Hees VT, Paquet C, Sommerlad A, et al. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun. 2021 Apr 20;12(1):2289. Suarez EC. Self-reported symptoms of sleep disturbance and inflammation, coagulation, insulin resistance and psychosocial distress: evidence for gender disparity. Brain Behav Immun. 2008;22(6):960-968. Scott AJ, Webb TL, Martyn-St James M, Rowse G, Weich S. Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials. Sleep Med Rev. 2021;60:101556. Baglioni C, Battagliese G, Feige B, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. J Affect Disord. 2011;135(1-3):10-19. Poceta JS. Zolpidem ingestion, automatisms, and sleep driving: a clinical and legal case series. J Clin Sleep Med. 2011;7(6):632-638. Benington JH, Woudenberg MC, Heller HC. Apamin, a selective SK potassium channel blocker, suppresses REM sleep without a compensatory rebound. Brain Res. 1995;692(1-2):86-92. Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169. Sutanto CN, Loh WW, Kim JE. The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression. Nutr Rev. 2022;80(2):306-316. Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia. J Clin Endocrinol Metab. 2001;86(10):4727-4730. Zick SM, Wright BD, Sen A, Arnedt JT. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study. BMC Complement Altern Med. 2011;11:78. Drennan MD, Kripke DF, Klemfuss HA, Moore JD. Potassium affects actigraph-identified sleep. Sleep. 1991;14(4):357-360. Jadidi A, Rezaei Ashtiani A, Khanmohamadi Hezaveh A, Aghaepour SM. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial. BMC Complement Med Ther. 2022;23(1):1. Kukula-Koch W, Szwajgier D, Gaweł-Bęben K, Strzępek-Gomółka M, Głowniak K, Meissner HO. Is Phytomelatonin Complex Better Than Synthetic Melatonin? The Assessment of the Antiradical and Anti-Inflammatory Properties. Molecules. 2021;26(19):6087. Rao TP, Ozeki M, Juneja LR. In Search of a Safe Natural Sleep Aid. J Am Coll Nutr. 2015;34(5):436-447. Ohashi M, Lee SI, Eto T, et al. Intake of L-serine before bedtime prevents the delay of the circadian phase in real life. J Physiol Anthropol. 2022;41(1):31. Maffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020;22(1):181. Harvey BH, Brink CB, Seedat S, Stein DJ. Defining the neuromolecular action of myo-inositol: application to obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2002;26(1):21-32. Tan DX, Manchester LC, Qin L, Reiter RJ. Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics. Int J Mol Sci. 2016;17(12):2124. Reiter RJ, Ma Q, Sharma R. Melatonin in Mitochondria: Mitigating Clear and Present Dangers. Physiology (Bethesda). 2020;35(2):86-95. Altura BM, Altura BT. Tension headaches and muscle tension: is there a role for magnesium?. Med Hypotheses. 2001;57(6):705-713. Patel AK, Reddy V, Shumway KR, et al. Physiology, Sleep Stages. [Updated 2022 Sep 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan. Heizhati M, Zhang Y, Shao L, et al. Decreased serum potassium may disturb sleep homeostasis in essential hypertensives. Hypertens Res. 2019;42(2):174-181. Deac OM, Mills JL, Shane B, et al. Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults. J Nutr. 2015;145(4):701-707. Richard DM, Dawes MA, Mathias CW, Acheson A, Hill-Kapturczak N, Dougherty DM. L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. Int J Tryptophan Res. 2009;2:45-60. Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007;74(1):39-45. Williams JL, Everett JM, D’Cunha NM, et al. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review. Plant Foods Hum Nutr. 2020;75(1):12-23. Hidese S, Ogawa S, Ota M, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019;11(10):2362. Kikuchi AM, Tanabe A, Iwahori Y. A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning. J Diet Suppl. 2021;18(3):316-333. Jenkins TA, Nguyen JC, Polglaze KE, Bertrand PP. Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis. Nutrients. 2016;8(1):56. Hudson C, Hudson SP, Hecht T, MacKenzie J. Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia. Nutr Neurosci. 2005;8(2):121-127. Sutanto CN, Loh WW, Kim JE. The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression. Nutr Rev. 2022;80(2):306-316. Ye L, Sun Y, Jiang Z, Wang G. L-Serine, an Endogenous Amino Acid, Is a Potential Neuroprotective Agent for Neurological Disease and Injury. Front Mol Neurosci. 2021;14:726665. Cox PA, Metcalf JS. Traditional Food Items in Ogimi, Okinawa: l-Serine Content and the Potential for Neuroprotection. Curr Nutr Rep. 2017;6(1):24-31. Yasuo S, Iwamoto A, Lee SI, et al. l-Serine Enhances Light-Induced Circadian Phase Resetting in Mice and Humans. J Nutr. 2017;147(12):2347-2355. Bolsius YG, Zurbriggen MD, Kim JK, et al. The role of clock genes in sleep, stress and memory. Biochem Pharmacol. 2021;191:114493. Yasuo S, Iwamoto A, Lee SI, et al. l-Serine Enhances Light-Induced Circadian Phase Resetting in Mice and Humans. J Nutr. 2017;147(12):2347-2355. Ohashi M, Lee SI, Eto T, et al. Intake of L-serine before bedtime prevents the delay of the circadian phase in real life. J Physiol Anthropol. 2022;41(1):31. Maffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020;22(1):181. Meloni M, Figorilli M, Carta M, et al. Preliminary finding of a randomized, double-blind, placebo-controlled, crossover study to evaluate the safety and efficacy of 5-hydroxytryptophan on REM sleep behavior disorder in Parkinson’s disease. Sleep Breath. 2022;26(3):1023-1031. Sutanto C, Heng CW, Gan AX, Wang X, Fam J, Kim JE. The Impact of 5-Hydroxytryptophan Supplementation on Sleep Quality of Older Adults in Singapore: A Randomized Controlled Trial. Curr Dev Nutr. 2021;5(Suppl 2):372. DiNicolantonio JJ, H O’Keefe J. Myo-inositol for insulin resistance, metabolic syndrome, polycystic ovary syndrome and gestational diabetes. Open Heart. 2022;9(1):e001989. Wei H, Landgraf D, Wang G, McCarthy MJ. Inositol polyphosphates contribute to cellular circadian rhythms: Implications for understanding lithium’s molecular mechanism. Cell Signal. 2018;44:82-91. Bojarskaite L, Bjørnstad DM, Pettersen KH, et al. Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep. Nat Commun. 2020;11(1):3240. Engels G, Brinckmann J. Chamomile Matricaria chamomilla (syn. M. recutita, Chamomilla recutita) Family: Asteraceae. Herbalgram. 2023;108:8-17. Zick SM, Wright BD, Sen A, Arnedt JT. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study. BMC Complement Altern Med. 2011;11:78.